{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T10:39:50Z","timestamp":1774521590557,"version":"3.50.1"},"reference-count":17,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Septic emboli are commonly attributed to infective endocarditis and can present with a variety of symptoms including altered mental status and focal neurological deficits. Here, we reviewed images of septic emboli with hemorrhagic conversion in a patient with sepsis and a psoas abscess. We aim to show the classical image findings in septic embolism to brain, which is sparsely described in literature and the report differentiates the septic embolism from disseminated intravascular coagulation which can present with almost identical image findings.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 53-year-old male patient who was operated on for a right inguinal hernia developed a postoperative wound infection 2 weeks after surgery and was started on IV antibiotics. Despite medical management, his infection did not improve, prompting a computed tomography (CT) scan which revealed a psoas abscess. The abscess was drained, and antibiotics continued. A few days later, he developed altered sensorium prompting a head CT which revealed septic emboli and hemorrhage at the gray-white junction. Cultures grew multidrug-resistant <jats:italic>Escherichia coli<\/jats:italic>; the patient was treated with IV tigecycline and improved over the following 4 weeks.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>In patients with a known ongoing infectious process with hemodynamic stability who develop altered mental status in the setting of a normal coagulation profile, D-dimer, positive blood cultures, and absent signs of multiorgan failure, a diagnosis of septic emboli should be entertained. Although CT can reveal macrobleeds, MRI is more sensitive in confirming cerebral microbleeds. Thus, patients in sepsis with unexplained altered sensorium should undergo an MRI of the brain to rule out septic emboli and microbleeds.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_810_2020","type":"journal-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T09:27:18Z","timestamp":1643189238000},"page":"185","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multiple cerebral hemorrhages in sepsis-disseminated intravascular coagulation versus septic embolism: An image report"],"prefix":"10.25259","volume":"12","author":[{"given":"Omar","family":"Akel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bharath","family":"Raju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumatha Channapatna","family":"Suresh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fareed","family":"Jumah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaurav","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil","family":"Nanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,4,26]]},"reference":[{"key":"10.25259\/SNI_810_2020\/ref-1","doi-asserted-by":"crossref","first-page":"720","DOI":"10.2214\/AJR.07.2249","article-title":"MRI of cerebral microhemorrhages","volume":"189","author":"Blitstein","year":"2007","journal-title":"AJR Am J Roentgenol"},{"key":"10.25259\/SNI_810_2020\/ref-2","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s10096-015-2523-6","article-title":"Value of brain MRI 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review","volume":"33","author":"Ducruet","year":"2010","journal-title":"Neurosurg Rev"},{"key":"10.25259\/SNI_810_2020\/ref-6","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1159\/000348317","article-title":"Infective endocarditis with symptomatic cerebral complications: Contribution of cerebral magnetic resonance imaging","volume":"35","author":"Goulenok","year":"2013","journal-title":"Cerebrovasc Dis"},{"key":"10.25259\/SNI_810_2020\/ref-7","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1474-4422(09)70013-4","article-title":"Cerebral microbleeds: A guide to detection and interpretation","volume":"8","author":"Greenberg","year":"2009","journal-title":"Lancet Neurol"},{"key":"10.25259\/SNI_810_2020\/ref-8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1148\/radiol.2018170803","article-title":"Cerebral microbleeds: Imaging and clinical 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therapies","volume":"311","author":"Miranda","year":"2016","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.25259\/SNI_810_2020\/ref-12","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1001\/jamaneurol.2013.223","article-title":"Extensive cerebral microhemorrhages caused by acute disseminated intravascular coagulation secondary to sepsis","volume":"71","author":"Neligan","year":"2014","journal-title":"JAMA Neurol"},{"key":"10.25259\/SNI_810_2020\/ref-13","doi-asserted-by":"crossref","first-page":"e2010024","DOI":"10.4084\/mjhid.2010.024","article-title":"Sepsis-associated disseminated intravascular coagulation and thromboembolic disease","volume":"2","author":"Semeraro","year":"2010","journal-title":"Mediterr J Hematol Infect Dis"},{"key":"10.25259\/SNI_810_2020\/ref-14","doi-asserted-by":"crossref","first-page":"58","DOI":"10.4103\/2229-5151.109423","article-title":"Septic embolism in the intensive care 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