{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T10:31:01Z","timestamp":1767349861687,"version":"3.48.0"},"reference-count":26,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Paragangliomas of the cauda equina are rare neuroendocrine tumors that can mimic ependymomas on imaging and histology, creating diagnostic challenges and influencing surgical planning.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n A 41-year-old man presented with progressive low back pain and bilateral leg numbness. MRI showed a well-circumscribed, enhancing intradural extramedullary mass at L3. He underwent L3\u2013L4 laminectomy with gross-total microsurgical excision. Histopathology revealed pseudorosettes and uniform tumor cells, initially suggesting ependymoma; however, immunohistochemistry demonstrated strong synaptophysin and S100 positivity with negative GFAP and EMA, confirming a cauda equina paraganglioma. Postoperatively, the patient recovered fully and remained asymptomatic at 1-year follow-up.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Paragangliomas can closely resemble ependymomas, and accurate diagnosis requires immunohistochemistry. Complete surgical excision yields excellent outcomes, and individualized long-term imaging follow-up is recommended because recurrence, although uncommon, can occur.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_812_2025","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T08:29:11Z","timestamp":1764923351000},"page":"513","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare case of cauda equina paraganglioma histologically simulating ependymoma"],"prefix":"10.25259","volume":"16","author":[{"given":"Ebrahim Mohamd Kher","family":"Alyousef","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Saqr Hospital, Ras Al Khaimah, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bashayer Abdulla","family":"Alshamsi","sequence":"additional","affiliation":[{"name":"Department of medicine, Sheikh Shakhbout Medical City SSMC, Abudhabi, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahra Ali","family":"Almazrouei","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mohammed Bin Rashid University MBRU, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ammar","family":"Shahid Tanweer","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mohammed Bin Rashid University MBRU, Dubai, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tasnim Ebrahem","family":"Alyousef","sequence":"additional","affiliation":[{"name":"Department of Medicine, Gaziantep University, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaf Ebrahem","family":"Alyousef","sequence":"additional","affiliation":[{"name":"Department of Medicine, Gaziantep University, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"key":"10.25259\/SNI_812_2025\/ref-2","doi-asserted-by":"crossref","first-page":"280","DOI":"10.3390\/jcm7090280","article-title":"The diagnosis and clinical significance of paragangliomas in unusual locations","volume":"7","author":"Asa","year":"2018","journal-title":"J Clin Med"},{"key":"10.25259\/SNI_812_2025\/ref-3","first-page":"269","article-title":"Paragangliomas of the cauda equina. 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