{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:48:54Z","timestamp":1761130134091},"reference-count":18,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nOsteoblastomas, although rare, are benign primary bone tumors, with cervical spine involvement being exceptionally uncommon. Late diagnosis, especially in aggressive cases, can lead to surgical challenges. Oxidized regenerated cellulose (ORC) used for hemostasis may result in complications if left in the surgical field.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nAn 8-year-old female presented with six months of intractable neck pain accompanied by swelling, hindering proximal right upper extremity evaluation. Motor strength was intact distally, with normal reflexes and no hypoesthesia. Imaging revealed a C4\u20135 facet joint lesion necessitating surgery. Intraoperative hemorrhage prompted ORC application, which led to postoperative arm pain and C5\u20136 radiculopathy. Subsequent surgery alleviated these symptoms.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nOsteoblastomas, despite their benign classification, may exhibit aggressive characteristics, warranting en-bloc<\/jats:italic> resection. Cervical spine osteoblastomas, due to their vascular nature and proximity to vital structures, complicate surgical interventions. ORC, a commonly used hemostatic agent, may induce compression complications, and early intervention is critical for patient recovery. This case underscores the intricacies of managing aggressive osteoblastomas in the cervical spine and highlights potential ORC-related complications. Surgeons must exercise caution when using ORC and consider postoperative risks. Prompt intervention and meticulous planning are paramount for favorable outcomes in such cases.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_854_2023","type":"journal-article","created":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T08:40:14Z","timestamp":1705653614000},"page":"20","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Aggressive osteoblastoma of the cervical spine and resultant complication due to swollen oxidized regenerated cellulose: A case report"],"prefix":"10.25259","volume":"15","author":[{"given":"Harun Emre","family":"Sen","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Kocaeli University, School of Medicine, Kocaeli, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Busra Yaprak","family":"Bayrak","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kocaeli University, School of Medicine, Kocaeli, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volkan","family":"Etus","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Kocaeli University, School of Medicine, Kocaeli, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,1,19]]},"reference":[{"key":"10.25259\/SNI_854_2023\/ref-1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00586-016-4904-7","article-title":"Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: A case report","volume":"26","author":"Ando","year":"2017","journal-title":"Eur Spine J"},{"key":"10.25259\/SNI_854_2023\/ref-2","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1007\/s00586-012-2395-8","article-title":"Staging and treatment of osteoblastoma in the mobile spine: A review of 51 cases","volume":"21","author":"Boriani","year":"2012","journal-title":"Eur Spine J"},{"key":"10.25259\/SNI_854_2023\/ref-3","first-page":"97","article-title":"Intraspinal oxidised cellulose (Surgicel) causing delayed paraplegia after thoracotomy--a report of three cases","volume":"84","author":"Brodbelt","year":"2002","journal-title":"Ann R Coll Surg Engl"},{"key":"10.25259\/SNI_854_2023\/ref-4","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/sj.sc.3101632","article-title":"Oxidised regenerated cellulose as a cause of paraplegia after thoracotomy: Case report and review of the literature","volume":"43","author":"Dogan","year":"2005","journal-title":"Spinal Cord"},{"key":"10.25259\/SNI_854_2023\/ref-5","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1186\/1471-2474-15-313","article-title":"Treatment of osteoblastoma at C3-4 in a child: A case report","volume":"15","author":"Feng","year":"2014","journal-title":"BMC Musculoskelet Disord"},{"key":"10.25259\/SNI_854_2023\/ref-6","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1097\/BRS.0b013e3181ba0024","article-title":"Aggressive \u201cbenign\u201d primary spine neoplasms: Osteoblastoma, aneurysmal bone cyst, and giant cell tumor","volume":"34","author":"Harrop","year":"2009","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.25259\/SNI_854_2023\/ref-7","doi-asserted-by":"crossref","first-page":"E9","DOI":"10.1016\/j.jpedsurg.2005.01.032","article-title":"Postoperative paraplegia secondary to the use of oxidized cellulose (Surgicel)","volume":"40","author":"Henry","year":"2005","journal-title":"J Pediatr Surg"},{"key":"10.25259\/SNI_854_2023\/ref-8","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ijscr.2013.01.009","article-title":"Post thoracotomy spinal cord compression in a child. 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