{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T20:24:46Z","timestamp":1767990286884,"version":"3.49.0"},"reference-count":15,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Rosai\u2013Dorfman disease (RDD) is an uncommon histiocytic proliferative disorder that typically involves the lymph nodes but can also present with extranodal involvement. Central nervous system involvement is rare, and the spine-restricted RDD is an extremely rare variant that poses significant diagnostic challenges, often resulting in delays in diagnosis and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Case Description:<\/jats:title>\n                    <jats:p>We report a case of a 32-year-old gentleman with a history of back pain for 1-year, initially being managed as ankylosing spondylitis, which subsequently developed spastic paraparesis and was ultimately diagnosed with spine-restricted RDD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Recognizing this rare entity and its potential associations with immune-mediated conditions, such as human leukocyte antigen B27-related spondyloarthropathies and possibly inflammatory bowel disease, is essential to avoid misdiagnosis and guide individualized, multidisciplinary treatment strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.25259\/sni_876_2025","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T15:13:01Z","timestamp":1767971581000},"page":"21","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spine-limited Rosai\u2013Dorfman disease in a patient with ankylosing spondylitis \u2013 A rare mimicker of spinal tumors"],"prefix":"10.25259","volume":"17","author":[{"given":"Mehar","family":"Masroor","sequence":"first","affiliation":[{"name":"Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zanib","family":"Javed","sequence":"additional","affiliation":[{"name":"Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Gilani","sequence":"additional","affiliation":[{"name":"Department of Pathology, Phoenix Children\u2019s Hospital, Phoenix, Arizona, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahzad M.","family":"Shamim","sequence":"additional","affiliation":[{"name":"Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"10.25259\/SNI_876_2025\/ref-1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/s41394-023-00600-7","article-title":"Spinal Rosai-Dorfman disease: A report of 2 cases and review of literature","volume":"9","author":"Basu","year":"2023","journal-title":"Spinal Cord Ser Cases"},{"key":"10.25259\/SNI_876_2025\/ref-2","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1177\/19714009241303077","article-title":"Radiology-pathology correlation: Rosai-Dorfman disease","volume":"38","author":"Benson","year":"2025","journal-title":"Neuroradiol J"},{"key":"10.25259\/SNI_876_2025\/ref-3","first-page":"1169","article-title":"Adenitis with lipid excess, in children or young adults, seen in the Antilles and in Mali (4 cases)","volume":"58","author":"Destombes","year":"1965","journal-title":"Bull Soc Pathol Exot Filiales"},{"key":"10.25259\/SNI_876_2025\/ref-4","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1007\/s10620-024-08596-2","article-title":"Gastrointestinal manifestations of RosaiDorfman disease","volume":"69","author":"Gendy","year":"2024","journal-title":"Dig Dis Sci"},{"key":"10.25259\/SNI_876_2025\/ref-5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0929-6646(09)60197-2","article-title":"Clinicopathologic characteristics of Rosai-Dorfman disease in a medical center in northern Taiwan","volume":"105","author":"Hsiao","year":"2006","journal-title":"J Formos Med Assoc"},{"key":"10.25259\/SNI_876_2025\/ref-6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13643-021-01581-0","article-title":"Diagnosis and treatment of Rosai-Dorfman disease of the spine: A systematic literature review","volume":"10","author":"Hu","year":"2021","journal-title":"Syst Rev"},{"key":"10.25259\/SNI_876_2025\/ref-7","first-page":"16","article-title":"Spinal extradural Rosai Dorfman disease","volume":"14","author":"James","year":"2017","journal-title":"Eur J Gen Med"},{"key":"10.25259\/SNI_876_2025\/ref-8","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.radcr.2020.01.026","article-title":"RosaiDorfman disease with paravertebral and epidural thoracic spine involvement: A case report and literature review","volume":"15","author":"Jayaram","year":"2020","journal-title":"Radiol Case 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A newly recognized benign clinicopathological entity","volume":"87","author":"Rosai","year":"1969","journal-title":"Arch Pathol"},{"key":"10.25259\/SNI_876_2025\/ref-12","doi-asserted-by":"crossref","first-page":"e35654","DOI":"10.1097\/MD.0000000000035654","article-title":"Cervical spine Rosai-Dorfman disease: A case report and literature review","volume":"102","author":"Rao","year":"2023","journal-title":"Medicine (Baltimore)"},{"key":"10.25259\/SNI_876_2025\/ref-13","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1001\/jamadermatol.2013.7609","article-title":"Possible association of cutaneous RosaiDorfman disease and chronic Crohn disease: A case series report","volume":"150","author":"Salva","year":"2014","journal-title":"JAMA Dermatol"},{"key":"10.25259\/SNI_876_2025\/ref-14","doi-asserted-by":"crossref","first-page":"108206","DOI":"10.1016\/j.clineuro.2024.108206","article-title":"Isolated Rosai-Dorfman disease of the spine: A systematic literature review","volume":"239","author":"Slouma","year":"2024","journal-title":"Clin Neurol Neurosurg"},{"key":"10.25259\/SNI_876_2025\/ref-15","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1186\/s13019-024-03147-2","article-title":"Extranodal Rosai-Dorfman disease masquerading as intrathoracic invasive malignancy with ankylosing spondylitis: A case report","volume":"19","author":"Xu","year":"2024","journal-title":"J Cardiothorac Surg"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/spine-limited-rosaidorfman-disease-in-a-patient-with-ankylosing-spondylitis-a-rare-mimicker-of-spinal-tumors\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/spine-limited-rosaidorfman-disease-in-a-patient-with-ankylosing-spondylitis-a-rare-mimicker-of-spinal-tumors\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T15:13:03Z","timestamp":1767971583000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/spine-limited-rosaidorfman-disease-in-a-patient-with-ankylosing-spondylitis-a-rare-mimicker-of-spinal-tumors\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,9]]},"references-count":15,"alternative-id":["10.25259\/SNI_876_2025"],"URL":"https:\/\/doi.org\/10.25259\/sni_876_2025","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1,9]]},"article-number":"21"}}