{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:56:57Z","timestamp":1787025417346,"version":"build-2736575974"},"reference-count":27,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Linear accelerator (LINAC)-based stereotactic radiosurgery (SRS) treatment of trigeminal neuralgia (TN) may have similar efficacy to Gamma Knife SRS (GK-SRS), but the preponderance of data comes from patients treated with GK-SRS. Our objective was to analyze the outcomes for LINAC-based treatment of TN in patients at our institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We retrospectively analyzed data for patients who underwent LINAC-based SRS for TN from 2006 to 2018. Data were collected from the patients\u2019 medical records. Nonparametric statistics were used for the analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the 41 patients treated with LINAC-based SRS (typically 90 Gy dosed using a 4 mm collimator for one fraction) during that time, follow-up data of &gt;3 weeks post-SRS were available for 32 patients. The median pretreatment Barrow Neurological Institute (BNI) pain score was 5 (range 4\u20135). The follow-up period ranged from 0.9 to 113.2 months (median 5 months). There was significant improvement in postradiation BNI pain score (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001), with 23 (72%) patients who improved to a BNI pain score of 1\u20133. One patient had bothersome hypoesthesia postradiation. Approximately 38% of patients who had initial pain control had recurrence of symptoms (BNI &gt; 3). Survival analysis showed a median time to pain recurrence of 30 months. There was no relationship between prior microvascular decompression (MVD) surgery and change in BNI pain score pre- to posttreatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The results demonstrate that LINAC-based SRS is an effective means to treat TN. Prior MVD surgery did not affect efficacy of SRS in lowering the BNI score from pre- to posttreatment in this patient cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.25259\/sni_91_2022","type":"journal-article","created":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T06:40:11Z","timestamp":1654843211000},"page":"246","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Outcomes using linear accelerator stereotactic radiosurgery for the treatment of trigeminal neuralgia: A single-center, retrospective study"],"prefix":"10.25259","volume":"13","author":[{"given":"Bornali","family":"Kundu","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Utah, Salt Lake City, Utah, United States."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea A.","family":"Brock","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Utah, Salt Lake City, Utah, United States."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason G.","family":"Garry","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Utah, Salt Lake City, Utah, United States."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randy L.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Utah, Salt Lake City, Utah, United States."},{"name":"Department of Radiation Oncology, University of Utah, Salt Lake City, Utah, United States."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay M.","family":"Burt","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Utah, Salt Lake City, Utah, United States."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald M.","family":"Cannon","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University 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