{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T17:27:49Z","timestamp":1649006869086},"reference-count":2,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Primary spinal tumors are rare benign lesions that represent around 2\u20134% of all central nervous system neoplasms.[1,2] Intradural intramedullary tumors are predominately glial in origin and are most commonly astrocytomas or ependymomas. Intradural extramedullary tumors, on the other hand, are usually neurofibromas, schwannomas, or meningiomas.[2] Here, we report the case of an intradural intramedullary collision tumor of schwannoma-hemangioblastoma origin.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 61-year-old female presented with a 2-year history of the right arm numbness, weakness, and tingling. She reported some lower extremity numbness but an otherwise normal neurological examination. She had a prior carpal tunnel release that did not alleviate her symptoms. Noncontrast MRI of the cervical spine demonstrated a holocord syrinx from C2 to C7 and spondylolisthesis from C4 to C5. MRI with contrast then displayed an enhancing nodule behind the vertebral body of C4. A standard posterior approach and subperiosteal dissection were performed. Lateral mass screws were placed at C3-C5, and the laminectomy was performed <jats:italic>en bloc<\/jats:italic>. Intraoperative ultrasound was used to locate the lesion, and intraoperative dorsal column mapping was used to identify the midline before performing a midline myelotomy. The arachnoid over the lesion was opened and an extracapsular dissection was performed. Hemostasis was obtained, and a watertight dural closure was performed.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>The patient tolerated the procedure well and achieved relief from cervical myelopathy symptoms. Pathology indicated positive biomarkers for S-100, SOX10, and NSE indicating a schwannoma hemangioblastoma collision tumor. This is unusual in its nature given two benign lesions with differing underlying cell types of origin.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_92_2021","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T10:08:11Z","timestamp":1618481291000},"page":"155","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cervical intradural intramedullary collision tumor of schwannoma and hemangioblastoma origin"],"prefix":"10.25259","volume":"12","author":[{"given":"Rohin","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maziyar","family":"Kalani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,4,14]]},"reference":[{"key":"10.25259\/SNI_92_2021\/ref-1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.wneu.2018.07.007","article-title":"Primary Spinal cord small-cell glioblastoma: Case report and literature review","volume":"118","author":"Caro-Osorio","year":"2018","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_92_2021\/ref-2","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1586\/ern.09.101","article-title":"Adult primary spinal cord tumors","volume":"9","author":"Grimm","year":"2009","journal-title":"Expert Rev Neurother"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/cervical-intradural-intramedullary-collision-tumor-of-schwannoma-and-hemangioblastoma-origin\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/cervical-intradural-intramedullary-collision-tumor-of-schwannoma-and-hemangioblastoma-origin\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T10:08:12Z","timestamp":1618481292000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/cervical-intradural-intramedullary-collision-tumor-of-schwannoma-and-hemangioblastoma-origin\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,14]]},"references-count":2,"alternative-id":["10.25259\/SNI_92_2021"],"URL":"https:\/\/doi.org\/10.25259\/sni_92_2021","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,14]]},"article-number":"155"}}