{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T14:36:45Z","timestamp":1768315005715,"version":"3.49.0"},"reference-count":9,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nSome reports are suggesting the efficacy of continuous irrigation therapy for brain abscesses, but the way how to irrigate and perfusion abscesses and cerebral spinal fluid has not yet been established. Here, we present the case of successfully treated by continuous irrigation therapy for the severe bacterial brain abscess, meningitis, and encephalitis.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nA 62-year-old man presented to our hospital with a chief complaint of headache and vomiting. Magnetic resonance imaging revealed an encapsulated lesion with peripheral contrast in the left cerebellar hemisphere, and the lesion showed high signal intensity on diffusion-weighted imaging. We diagnosed him with a brain abscess. In addition to drainage of the cerebellar lesion by small craniotomy and systemic administration of antibiotics, continuous irrigation therapy was performed for 7 days until the cell count of the cerebrospinal fluid became negative. Saline with antibiotics was infused through from ventricular drain, which was inserted through the anterior horn of the lateral ventricle to spiral drainage. His state of consciousness improved, and he was able to live at home.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nOur proposed novel continuous irrigation therapy may lead to a positive outcome in brain abscesses.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_940_2024","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T09:32:36Z","timestamp":1738920756000},"page":"36","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A case of brain abscess successfully treated with continuous irrigation therapy"],"prefix":"10.25259","volume":"16","author":[{"given":"Takuma","family":"Takano","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Sapporo Higashi Tokushukai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nakao","family":"Ota","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomasa","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Shonantobu General Hospital, Chigasaki, Kanagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Kusunoki","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soichiro","family":"Yasuda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keita","family":"Toh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuaki","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoya","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosumo","family":"Noda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadahisa","family":"Tokuda","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rokuya","family":"Tanikawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Sapporo Teishinkai Hospital, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2025,2,7]]},"reference":[{"key":"10.25259\/SNI_940_2024\/ref-1","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1212\/WNL.0000000000000172","article-title":"Clinical characteristics and outcome of brain abscess: Systematic review and meta-analysis","volume":"82","author":"Brouwer","year":"2014","journal-title":"Neurology"},{"key":"10.25259\/SNI_940_2024\/ref-2","doi-asserted-by":"crossref","first-page":"630","DOI":"10.2176\/nmc.37.630","article-title":"Treatment of brain abscess associated with ventricular rupture--three case reports","volume":"37","author":"Isono","year":"1997","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.25259\/SNI_940_2024\/ref-3","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s12987-022-00382-4","article-title":"Measurements of cerebrospinal fluid production: A review of the limitations and advantages of current methodologies","volume":"19","author":"Liu","year":"2022","journal-title":"Fluids Barriers CNS"},{"key":"10.25259\/SNI_940_2024\/ref-4","doi-asserted-by":"crossref","first-page":"518","DOI":"10.3389\/fneur.2018.00518","article-title":"Multidrug resistant brain abscess due to Acinetobacter baumannii ventriculitis cleared by intraventricular and intravenous 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A case report","volume":"22","author":"Sato","year":"1994","journal-title":"No Shinkei Geka"},{"key":"10.25259\/SNI_940_2024\/ref-8","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/clind\/15.3.394","article-title":"Bacterial brain abscesses: Factors influencing mortality and sequelae","volume":"15","author":"Seydoux","year":"1992","journal-title":"Clin Infect Dis"},{"key":"10.25259\/SNI_940_2024\/ref-9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jvs.2008.07.076","article-title":"Complications of spinal fluid drainage in thoracoabdominal aortic aneurysm repair: A report of 486 patients treated from 1987 to 2008","volume":"49","author":"Wynn","year":"2009","journal-title":"J Vasc Surg"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/a-case-of-brain-abscess-successfully-treated-with-continuous-irrigation-therapy\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/a-case-of-brain-abscess-successfully-treated-with-continuous-irrigation-therapy\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T09:32:41Z","timestamp":1738920761000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/a-case-of-brain-abscess-successfully-treated-with-continuous-irrigation-therapy\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,7]]},"references-count":9,"alternative-id":["10.25259\/SNI_940_2024"],"URL":"https:\/\/doi.org\/10.25259\/sni_940_2024","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,7]]},"article-number":"36"}}