{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:33:36Z","timestamp":1756384416056},"reference-count":37,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Extraventricular neurocytoma (EVN) is an extremely rare neoplasm of the central nervous system. As reported, it arises in a variety of locations, but mainly within the cerebral hemispheres. Despite its histological similarity with central neurocytoma (CN), EVN occurs outside the ventricular system and, in 2007, was recognized by the World Health Organization as a separate entity.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 39-year-old man, with a ventriculoperitoneal shunt inserted for communicating hydrocephalus, was admitted at our Unit of Neurosurgery with a 1-month history of gait disturbance, postural instability, speech disorders, and occasional incontinence. Computed tomography scan and magnetic resonance imaging showed a mixed-density neoplasm in the left frontotemporal area, with anterior cerebral falx shift, and perilesional edema. The patient underwent surgical procedure; microsurgical excision of the lesion was performed through left pterional approach. Histopathological and immunohistochemical examination revealed monomorphic round cells of the neuronal lineage, with a percentage of Ki-67 positive nuclei &lt;5% and no evidence of mitosis or necrotic areas. According to radiologic features, this pattern was compatible with the diagnosis of EVN. Patient had a favorable recovery and he is still in follow-up.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>Because of their rarity, clinical, radiologic, and histopathological characteristics of EVNs are not yet well defined, as well as the optimal therapeutic management. Whereas EVNs are rarely described in literature, we aimed to share and discuss our experience along with a review of the published literature.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_951_2020","type":"journal-article","created":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T09:56:24Z","timestamp":1615197384000},"page":"88","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A rare diagnosis of an extraventricular neurocytoma"],"prefix":"10.25259","volume":"12","author":[{"given":"Claudia","family":"Gaggiotti","sequence":"first","affiliation":[{"name":"Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe Roberto","family":"Giammalva","sequence":"additional","affiliation":[{"name":"Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Raimondi","sequence":"additional","affiliation":[{"name":"Department of Scienze per la Promozione della Salute e Materno Infantile, Pathology Unit, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ada Maria","family":"Florena","sequence":"additional","affiliation":[{"name":"Department of Scienze per la Promozione della Salute e Materno Infantile, Pathology Unit, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa Maria","family":"Gerardi","sequence":"additional","affiliation":[{"name":"Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Graziano","sequence":"additional","affiliation":[{"name":"Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana","family":"Tumbiolo","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Emergency, Division of Neurosurgery, Villa Sofia Hospital, Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico Gerardo","family":"Iacopino","sequence":"additional","affiliation":[{"name":"Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario","family":"Maugeri","sequence":"additional","affiliation":[{"name":"Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,3,8]]},"reference":[{"key":"10.25259\/SNI_951_2020\/ref-1","doi-asserted-by":"crossref","first-page":"192","DOI":"10.3390\/brainsci8110192","article-title":"Brain mapping as helpful tool in brain glioma surgical treatment-toward the \u201cperfect surgery\u201d?","volume":"8","author":"Barone","year":"2018","journal-title":"Brain Sci"},{"key":"10.25259\/SNI_951_2020\/ref-2","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1097\/00000478-200110000-00005","article-title":"Extraventricular neurocytomas: Pathologic features and clinical outcome","volume":"25","author":"Brat","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"10.25259\/SNI_951_2020\/ref-3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.wneu.2018.01.104","article-title":"Extraventricular neurocytoma in the left frontal lobe: A case report and literature review","volume":"112","author":"Chen","year":"2018","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_951_2020\/ref-4","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jocn.2018.04.015","article-title":"Central neurocytoma: Clinical characteristics, patterns of care, and survival","volume":"53","author":"Dutta","year":"2018","journal-title":"J Clin Neurosci"},{"key":"10.25259\/SNI_951_2020\/ref-5","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3171\/jns.1997.87.1.0100","article-title":"Neurocytoma in the cerebellum. 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