{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T14:38:59Z","timestamp":1718289539900},"reference-count":16,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nFungal origin mycotic aneurysms are rare and carry a high mortality rate. Scedosporium apiospermum<\/jats:italic> is an ubiquitous fungus which has been described to cause devastating infections in immunocompromised hosts.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nWe report a case of a 23-year-old patient with Burkitt\u2019s lymphoma and graft-versus-host disease admitted with intracerebral hemorrhage and sequential development of 12 anterior circulation aneurysms from disseminated Scedosporium<\/jats:italic> infection. Despite aggressive surgical and antimicrobial treatment, the patient died 6 months later from multiorgan failure. The notable feature of this case is the rapid angioinvasiveness of the infection with new aneurysm formation within days of clear angiographic imaging despite the apparent lack of skull base osteomyelitis.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nWe highlight the difficulties in treating fungal mycotic aneurysms and the associated high mortality. While a less aggressive approach might have been appropriate given the known poor outcomes, the age of the patients as well as the family wishes dictated the treatment decisions.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_970_2021","type":"journal-article","created":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T10:36:17Z","timestamp":1654857377000},"page":"242","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Rapid sequential development and rupture of mycotic aneurysms within a period of days in a patient with graft-versus-host disease and angiotropic Scedosporium apiospermum<\/i> infection"],"prefix":"10.25259","volume":"13","author":[{"given":"Karol P.","family":"Budohoski","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of California San Francisco, San Francisco, California, Unites States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunal","family":"Raygor","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California San Francisco, San Francisco, California, Unites States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Cook","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of California San Francisco, San Francisco, California, Unites States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Henrich","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco, San Francisco, California, Unites States."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adib A.","family":"Abla","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California San Francisco, San Francisco, California, Unites States."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,6,10]]},"reference":[{"key":"10.25259\/SNI_970_2021\/ref-1","first-page":"321","article-title":"Fungal mycotic aneurysms and multiple cerebral abscesses caused by Scedosporium apiospermum. 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