{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T14:26:33Z","timestamp":1773239193463,"version":"3.50.1"},"reference-count":0,"publisher":"HMP Communications, LLC","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wounds"],"abstract":"<jats:p>Background. Below-knee amputation (BKA) and above-knee amputation (AKA) are often last-resort treatment options for chronic lower extremity (LE) wounds. Objective. To compare, for the first time, patient-reported outcome measures (PROMs) in patients who underwent BKA or AKA for nontraumatic chronic LE wounds. Methods. PROMs (20-item Self-Reporting Questionnaire [SRQ-20], Patient-Reported Outcomes Measurement Information System Pain Intensity 3-item scale [PROMIS-3a], Connor-Davidson Resilience Scale [CD-RISC], and Lower Extremity Functional Scale [LEFS]) were collected for patients who underwent AKA or BKA and who presented to a tertiary wound center between June 2022 and October 2024. Mental well-being (SRQ-20), pain intensity (PROMIS-3a), resilience (CD-RISC), and function (LEFS) were measured at 1 month, 3 months, 6 months, 1 year, 2 years, and 5 years postoperative. Results. Of 96 patients, 22 (22.9%) underwent AKA and 74 (77.1%) underwent BKA. Significant differences were observed between patients who underwent AKA versus BKA in mean (SD) overall function (LEFS, 33.9 [13.7] vs 47.4 [25.2]; P = .003), psychological distress (SRQ-20, 5.6 [4.3] vs 3.1 [3.9]; P = .002), and pain intensity (PROMIS-3a, 58.9 [10.4] vs 48.2 [13]; P = .001). Conclusion. The study results indicate that patients who have undergone AKA have higher pain intensity, more psychological distress, and lower function compared with patients who have undergone BKA. These findings underly the importance of performing a BKA when possible.<\/jats:p>","DOI":"10.25270\/wnds\/25060","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T18:28:12Z","timestamp":1773167292000},"source":"Crossref","is-referenced-by-count":0,"title":["Patient-Reported Outcomes Favor Below-Knee Over Above-Knee Amputation in Patients With Nontraumatic Lower Extremity Wounds"],"prefix":"10.25270","volume":"37","author":[{"suffix":"MD","given":"Ryan P.","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"MS","given":"Danny S.","family":"Chamaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"MS","given":"Sami","family":"Ferdousian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"BS","given":"Rachel N.","family":"Rohrich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"BS","given":"Isabel","family":"Snee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"MD","given":"Richard C.","family":"Youn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"MD","given":"Karen K.","family":"Evans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"MD","given":"Christopher E.","family":"Attinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10906","published-online":{"date-parts":[[2025,11]]},"container-title":["Wounds: a compendium of clinical research and practice"],"original-title":[],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T18:28:12Z","timestamp":1773167292000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hmpgloballearningnetwork.com\/site\/wounds\/original-research\/patient-reported-outcomes-favor-below-knee-over-above-knee-amputation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":0,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,11]]}},"URL":"https:\/\/doi.org\/10.25270\/wnds\/25060","relation":{},"ISSN":["1943-2704"],"issn-type":[{"value":"1943-2704","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11]]}}}