{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T14:07:13Z","timestamp":1769350033228,"version":"3.49.0"},"reference-count":67,"publisher":"MIS Quarterly","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,1]]},"abstract":"<jats:p>Asthma is a prevalent respiratory chronic disease affecting a large portion of the global population. Patients diagnosed with asthma may experience significantly reduced quality of life if their asthma is not properly controlled. To facilitate better asthma self-management, asthma specialists and engineers have developed the smart asthma management system (SAM). This new health information system provides Bluetooth-enabled inhalers and collects time stamps of every rescue inhaler use. Such detailed inhaler usage logs, which are crucial for investigating patterns of inhaler usage, were not available in traditional clinical trials because clinical trials acquire data only periodically. Due to the low data collection resolution of clinical trials, quantitative asthma studies based on trial data have been focusing mainly on capturing the increasing trend in the number of rescue inhaler uses. Taking advantage of the patient monitoring capability of the SAM system, we developed a data analytics framework for detecting abnormal inhaler use that is out of the patient\u2019s normal usage pattern. The new statistical model developed in this paper can address the key features of the data collected from the SAM system such as the heterogeneous impact of environmental factors on inhaler usage behavior and the correlation structure governed by the patient\u2019s repetitive routines. We show the satisfactory performance of our data analytics framework through rigorous comparison with various benchmark methods. Furthermore, we give an in-depth discussion on our contribution to the information systems (IS) knowledge base and practical implications of our analytics framework to data-driven asthma management practice.<\/jats:p>","DOI":"10.25300\/misq\/2020\/15092","type":"journal-article","created":{"date-parts":[[2020,3,4]],"date-time":"2020-03-04T16:13:37Z","timestamp":1583338417000},"page":"285-304","source":"Crossref","is-referenced-by-count":25,"title":["A Data Analytics Framework for Smart Asthma Management Based on Remote Health Information Systems with Bluetooth-Enabled Personal Inhalers"],"prefix":"10.25300","volume":"44","author":[{"given":"Junbo","family":"Son","sequence":"first","affiliation":[{"name":"Alfred Lerner College of Business & Economics, University of Delaware, Newark, DE 19716 U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia Flatley","family":"Brennan","sequence":"additional","affiliation":[{"name":"National Library of Medicine, National Institutes of Health, Bethesda, MD 20894 U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiyu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Industrial & Systems Engineering, University of Wisconsin\u2013Madison, Madison, WI 53706 U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10933","published-online":{"date-parts":[[2020,3,1]]},"reference":[{"issue":"4","key":"2025090915511777700_b1-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1287\/isre.1100.0327","article-title":"The Digital Transformation of Healthcare: Current Status and the Road Ahead","volume":"21","author":"Agarwal","year":"2010","journal-title":"Information Systems Research"},{"key":"2025090915511777700_b2-11_15092_si_cd_sonbrennan","volume-title":"Categorical Data Analysis","author":"Agresti","year":"2001"},{"issue":"12","key":"2025090915511777700_b3-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"e313","DOI":"10.2196\/jmir.5866","article-title":"The Effectiveness of Web-Based Asthma Self-Management System, My Asthma Portal (MAP): A Pilot Randomized Controlled Trial","volume":"18","author":"Ahmed","year":"2016","journal-title":"Journal of Medical Internet Research"},{"issue":"2","key":"2025090915511777700_b4-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"5","DOI":"10.32614\/RJ-2015-017","article-title":"Fitting Conditional and Simultaneous Autoregressive Spatial Models in hglm","volume":"7","author":"Alam","year":"2015","journal-title":"The R Journal"},{"issue":"2-3","key":"2025090915511777700_b5-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1385\/CRIAI:31:2:163","article-title":"Agonists and Exercise-Induced Asthma","volume":"31","author":"Anderson","year":"2006","journal-title":"Clinical Reviews in Allergy & Immunology"},{"key":"2025090915511777700_b6-11_15092_si_cd_sonbrennan","article-title":"Observations of Daily Living: Putting the \u2018Personal\u2019 in Personal Health Records","author":"Backonja","year":"2012"},{"issue":"1","key":"2025090915511777700_b7-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1287\/isre.2014.0553","article-title":"Predictive Analytics for Readmission of Patients with Congestive Heart Failure","volume":"26","author":"Bardhan","year":"2015","journal-title":"Information Systems Research"},{"issue":"4","key":"2025090915511777700_b8-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1377\/hlthaff.2017.1315","article-title":"AIR Louisville: Addressing Asthma with Technology, Crowdsourcing, Cross-Sector, and Policy","volume":"37","author":"Barrett","year":"2017","journal-title":"Health Affairs"},{"issue":"3","key":"2025090915511777700_b9-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.jaci.2009.11.033","article-title":"Overall Asthma Control: The Relationship between Current Control and Future Risk","volume":"125","author":"Bateman","year":"2010","journal-title":"Journal of Allergy and Clinical Immunology"},{"issue":"1","key":"2025090915511777700_b10-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting Linear Mixed-Effects Models Using lme4","volume":"67","author":"Bates","year":"2015","journal-title":"Journal of Statistical Software"},{"issue":"4","key":"2025090915511777700_b11-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3109\/02770909809075667","article-title":"Psychological Factors Associated with Medication Nonadherence in Asthmatic Children","volume":"35","author":"Bender","year":"1998","journal-title":"Journal of Asthma"},{"issue":"2","key":"2025090915511777700_b12-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1145\/380995.380999","article-title":"Support Vector Machines: Hype or Hallelujah?","volume":"2","author":"Bennett","year":"2000","journal-title":"ACM SIGKDD Explorations"},{"issue":"3","key":"2025090915511777700_b13-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1377\/hlthaff.2011.0178","article-title":"The Benefits of Health Information Technology: A Review of the Recent Literature Shows Predominantly Positive Results","volume":"30","author":"Buntin","year":"2011","journal-title":"Health Affairs"},{"issue":"12","key":"2025090915511777700_b14-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.rmed.2004.04.001","article-title":"The Relationship Between Health-Related Quality of Life, Lung Function and Daily Symptoms in Patients with Persistent Asthma","volume":"98","author":"Carranza","year":"2004","journal-title":"Respiratory Medicine"},{"key":"2025090915511777700_b15-11_15092_si_cd_sonbrennan","first-page":"192","article-title":"Project HealthDesign: A Preliminary Program-level Report","author":"Casper","year":"2013"},{"key":"2025090915511777700_b16-11_15092_si_cd_sonbrennan","unstructured":"CDC\n          . 2016. \u201cData, Statistics, and Surveillance: Asthma Surveillance Data,\u201d National Center for Environmental Health, Center for Disease Control and Prevention (https:\/\/www.cdc.gov\/asthma\/most_recent_data.htm)."},{"issue":"3","key":"2025090915511777700_b17-11_15092_si_cd_sonbrennan","first-page":"335","article-title":"Using Electronic Monitoring Devices to Measure Inhaler Adherence: A Practical Guide for Clinicians","volume":"3","author":"Chan","year":"2015","journal-title":"Journal of Allergy and Clinical Immunology: In Practice"},{"issue":"3","key":"2025090915511777700_b18-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"27:1","DOI":"10.1145\/1961189.1961199","article-title":"LIBSVM: A Library for Support Vector Machines","volume":"2","author":"Chang","year":"2011","journal-title":"ACM Transactions on Intelligent Systems and Technology"},{"key":"2025090915511777700_b19-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"671","DOI":"10.2307\/2532003","article-title":"Empirical Bayes Estimates of Age Standardized Relative Risks for Use in Disease Mapping","volume":"43","author":"Clayton","year":"1987","journal-title":"Biometrics"},{"key":"2025090915511777700_b20-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1183\/09031936.03.00081102","article-title":"Assessment of Variations in Control of Asthma Over Time","volume":"22","author":"Combescure","year":"2003","journal-title":"European Respiratory Journal"},{"key":"2025090915511777700_b21-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","DOI":"10.1002\/9781119115151","volume-title":"Statistics for Spatial Data","author":"Cressie","year":"1993","edition":"Rev."},{"issue":"3","key":"2025090915511777700_b22-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1287\/isre.1110.0382","article-title":"The Role of Information Systems in Healthcare: Current Research and Future Trends","volume":"22","author":"Fichman","year":"2011","journal-title":"Information Systems Research"},{"issue":"2","key":"2025090915511777700_b23-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"337","DOI":"10.25300\/MISQ\/2013\/37.2.01","article-title":"Positioning and Presenting Design Science Research for Maximum Impact","volume":"37","author":"Gregor","year":"2013","journal-title":"MIS Quarterly"},{"issue":"58","key":"2025090915511777700_b24-11_15092_si_cd_sonbrennan","article-title":"The Evolution of Mobile Apps for Asthma: An Updated Systematic Assessment of Content and Tools","volume":"13","author":"Huckvale","year":"2015","journal-title":"BMC Medicine"},{"issue":"9","key":"2025090915511777700_b25-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1111\/cea.12138","article-title":"Perceived Triggers of Asthma: Key to Symptom Perception and Managemet","volume":"43","author":"Janssens","year":"2013","journal-title":"Clinical & Experimental Allergy"},{"key":"2025090915511777700_b26-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.cpr.2009.02.006","article-title":"Inaccurate Perception of Asthma Symptoms: A Cognitive\u2013Affective Framework and Implications for Asthma Treatment","volume":"29","author":"Janssens","year":"2009","journal-title":"Clinical Psychology Review"},{"issue":"4","key":"2025090915511777700_b27-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1287\/isre.2014.0544","article-title":"Patient Data as Medical Facts: Social Media Practices as a Foundation for Medical Knowledge Creation","volume":"25","author":"Kallinikos","year":"2014","journal-title":"Information Systems Research"},{"issue":"3","key":"2025090915511777700_b28-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1287\/isre.1100.0314","article-title":"IS Avoidance in Health-Care Groups: A Multilevel Investigation","volume":"22","author":"Kane","year":"2011","journal-title":"Information Systems Research"},{"key":"2025090915511777700_b29-11_15092_si_cd_sonbrennan","first-page":"37","article-title":"Using Connected Devices to Monitor Inhaler Use in the Real World","volume":"1","author":"Kim","year":"2016","journal-title":"Respiratory Drug Delivery"},{"issue":"5","key":"2025090915511777700_b30-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/j.1365-2222.1993.tb00339.x","article-title":"Grass Pollen, Thunderstorms, and Asthma","volume":"23","author":"Knox","year":"1993","journal-title":"Clinical & Experimental Allergy"},{"issue":"3","key":"2025090915511777700_b31-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"553","DOI":"10.25300\/MISQ\/2016\/40.3.02","article-title":"Electronic Health Records: How Can IS Researchers Contribute to Transforming Healthcare?","volume":"40","author":"Kohli","year":"2016","journal-title":"MIS Quarterly"},{"issue":"Supplement","key":"2025090915511777700_b32-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"w391","DOI":"10.1377\/hlthaff.27.5.w391","article-title":"Health Information Technology: Strategic Initiatives, Real Progress","volume":"27","author":"Kolodner","year":"2008","journal-title":"Health Affairs"},{"key":"2025090915511777700_b33-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1111\/j.2517-6161.1996.tb02105.x","article-title":"Hierarchical Generalized Linear Models (with Discussions)","volume":"58","author":"Lee","year":"1996","journal-title":"Journal of the Royal Statistical Society, Series B"},{"key":"2025090915511777700_b34-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1093\/biomet\/88.4.987","article-title":"Hierarchical Generalized Linear Models: A Synthesis of Generalized Linear Models, Random Effect Models, and Structured Dispersions","volume":"88","author":"Lee","year":"2001","journal-title":"Biometrika"},{"key":"2025090915511777700_b35-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","DOI":"10.1201\/9781420011340","volume-title":"Generalized Linear Models with Random Effects: Unified Analysis via H-Likelihood","author":"Lee","year":"2006"},{"issue":"3","key":"2025090915511777700_b36-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1109\/MIS.2014.52","article-title":"Smart and Connected Health","volume":"29","author":"Leroy","year":"2014","journal-title":"IEEE Intelligent Systems"},{"issue":"4","key":"2025090915511777700_b37-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1155\/2013\/906710","article-title":"Development and Pilot Testing of a Mobile Health Solution for Asthma Self-management: Asthma Action Plan Smartphone Application Pilot Study","volume":"20","author":"Licskai","year":"2013","journal-title":"Canadian Respiratory Journal"},{"issue":"2","key":"2025090915511777700_b38-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"473","DOI":"10.25300\/MISQ\/2017\/41.2.07","article-title":"Healthcare Predictive Analytics for Risk Profiling in Chronic Care: A Bayesian Multitask Learning Approach","volume":"41","author":"Lin","year":"2017","journal-title":"MIS Quarterly"},{"issue":"3","key":"2025090915511777700_b39-11_15092_si_cd_sonbrennan","first-page":"455","article-title":"Effectiveness of Population Health Management Using the Propeller Health Asthma Platform: A Randomized Clinical Trial","volume":"4","author":"Merchant","year":"2016","journal-title":"Journal of Allergy and Clinical Immunology: In Practice"},{"issue":"6","key":"2025090915511777700_b40-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0091-6749(96)80190-4","article-title":"Noncompliance and Treatment Failure in Children with Asthma","volume":"98","author":"Milgrom","year":"1996","journal-title":"Journal of Allergy and Clinical Immunology"},{"issue":"1","key":"2025090915511777700_b41-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jaci.2003.09.008","article-title":"Development of the Asthma Control Test: A Survey for Assessing Asthma Control","volume":"113","author":"Nathan","year":"2004","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"2025090915511777700_b42-11_15092_si_cd_sonbrennan","unstructured":"NHLBI\n          . 2007. National Asthma Education and Prevention Program, Third Expert Panel on the Diagnosis and Management of Asthma. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma, National Heart, Lung, and Blood Institute, Bethesda, MD (https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK7232\/)."},{"issue":"3","key":"2025090915511777700_b43-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1513\/AnnalsATS.201703-259OC","article-title":"The Economic Burden of Asthma in the United States, 2008\u20132013","volume":"15","author":"Nurmagambetov","year":"2017","journal-title":"Annals of the American Thoracic Society"},{"issue":"6","key":"2025090915511777700_b44-11_15092_si_cd_sonbrennan","first-page":"751","article-title":"Predictors of Severe Exacerbations, Poor Asthma Control, and -Agonist Overuse for Patients with Asthma","volume":"2","author":"Patel","year":"2014","journal-title":"Journal of Allergy and Clinical Immunology: In Practice"},{"key":"2025090915511777700_b45-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4419-0318-1","volume-title":"Mixed-Effects Models in S and S-PLUS","author":"Pinheiro","year":"2000"},{"issue":"Supplement 2","key":"2025090915511777700_b46-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"S133","DOI":"10.1016\/S1550-8579(07)80054-4","article-title":"Gender Differences in Asthma Development and Progression","volume":"4","author":"Postma","year":"2007","journal-title":"Gender Medicine"},{"key":"2025090915511777700_b47-11_15092_si_cd_sonbrennan","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2016"},{"issue":"1","key":"2025090915511777700_b48-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1164\/rccm.200801-060ST","article-title":"An Official American Thoracic Society\/European Respiratory Society Statement: Asthma Control and Exacerbations: Standardizing Endpoints for Clinical Asthma Trials and Clinical Practice","volume":"180","author":"Reddel","year":"2009","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"issue":"2","key":"2025090915511777700_b49-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"20","DOI":"10.32614\/RJ-2010-009","article-title":"hglm: A Package for Fitting Hierarchical Generalized Linear Models","volume":"2","author":"Ronnegard","year":"2010","journal-title":"The R Journal"},{"issue":"1","key":"2025090915511777700_b50-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1398-9995.2005.00953.x","article-title":"Are Overweight Asthmatics More Difficult to Control?","volume":"61","author":"Saint-Pierre","year":"2006","journal-title":"Allergy"},{"issue":"24","key":"2025090915511777700_b51-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"3755","DOI":"10.1002\/sim.1680","article-title":"The Analysis of Asthma Control under a Markov Assumption with Use of Covariates","volume":"22","author":"Saint-Pierre","year":"2003","journal-title":"Statistics in Medicine"},{"issue":"3","key":"2025090915511777700_b52-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jaci.2006.01.011","article-title":"Asthma Control Test: Reliability, Validity, and Responsiveness in Patients Not Previously Followed by Asthma Specialists","volume":"117","author":"Schatz","year":"2006","journal-title":"Journal of Allergy and Clinical Immunology"},{"issue":"3","key":"2025090915511777700_b53-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"553","DOI":"10.2307\/23042796","article-title":"Predictive Analytics in Information Systems Research","volume":"35","author":"Shmueli","year":"2011","journal-title":"MIS Quarterly"},{"issue":"1","key":"2025090915511777700_b54-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2143\/AST.32.1.1020","article-title":"Fitting Tweedie\u2019s Compound Poisson Model to Insurance Claims Data: Dispersion Modelling","volume":"32","author":"Smyth","year":"2002","journal-title":"ASTIN Bulletin"},{"key":"2025090915511777700_b55-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/(SICI)1099-095X(199911\/12)10:6<695::AID-ENV385>3.0.CO;2-M","article-title":"Adjusted Likelihood Methods for Modeling Dispersion in Generalized Linear Models","volume":"10","author":"Smyth","year":"1999","journal-title":"Environmetrics"},{"issue":"4","key":"2025090915511777700_b56-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1080\/0740817X.2015.1078014","article-title":"Rescue Inhaler Usage Prediction in Smart Asthma Management Systems Using Joint Mixed Effects Logistic Regression Model","volume":"48","author":"Son","year":"2016","journal-title":"IIE Transactions"},{"key":"2025090915511777700_b57-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1002\/sim.7214","article-title":"Correlated Gamma-Based Hidden Markov Model for the Smart Asthma Management Based on Rescue Inhaler Usage","volume":"36","author":"Son","year":"2017","journal-title":"Statistics in Medicine"},{"issue":"2","key":"2025090915511777700_b58-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1289\/EHP266","article-title":"Feasibility of Deploying Inhaler Sensors to Identify the Impacts of Environmental Triggers and Built Environment Factors on Asthma Short-Acting Bronchodilator Use","volume":"125","author":"Su","year":"2017","journal-title":"Environmental Health Perspective"},{"key":"2025090915511777700_b59-11_15092_si_cd_sonbrennan","unstructured":"United States Census Bureau\n          . 2016. Quick Facts Table: Kentucky (https:\/\/www.census.gov\/quickfacts\/KY)."},{"issue":"1","key":"2025090915511777700_b60-11_15092_si_cd_sonbrennan","first-page":"119","article-title":"Monitoring and Improving Compliance and Asthma Control: Mapping Inhaler Use for Feedback to Patients, Physicians, and Payers","author":"Van Sickle","year":"2013","journal-title":"Respiratory Drug Delivery"},{"issue":"11","key":"2025090915511777700_b61-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1890\/07-0043.1","article-title":"Quasi-Poisson vs. Negative Binomial Regression: How Should We Model Over-dispersed Count Data","volume":"88","author":"Ver Hoef","year":"2007","journal-title":"Ecology"},{"issue":"10","key":"2025090915511777700_b62-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"991","DOI":"10.3109\/02770903.2012.738268","article-title":"What Do We Know about Asthma Triggers? A Review of the Literature","volume":"49","author":"Vernon","year":"2012","journal-title":"Journal of Asthma"},{"key":"2025090915511777700_b63-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0378-3758(03)00111-3","article-title":"A Close Look at the Spatial Structure Implied by the CAR and SAR Models","volume":"121","author":"Wall","year":"2004","journal-title":"Journal of Statistical Planning and Inference"},{"key":"2025090915511777700_b64-11_15092_si_cd_sonbrennan","first-page":"439","article-title":"Quasi-Likelihood Functions, Generalized Linear Models, and the Gauss-Newton Method","volume":"61","author":"Wedderburn","year":"1974","journal-title":"Biometrika"},{"issue":"6","key":"2025090915511777700_b65-11_15092_si_cd_sonbrennan","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.jaci.2011.09.011","article-title":"Quantifying the Proportion of Severe Asthma Exacerbations Attributable to Inhaled Corticosteroid Nonadherence","volume":"128","author":"William","year":"2011","journal-title":"Journal of Allergy and Clinical Immunology"},{"issue":"3","key":"2025090915511777700_b66-11_15092_si_cd_sonbrennan","first-page":"446","article-title":"Mobile Health Applications for Asthma","volume":"3","author":"Wu","year":"2015","journal-title":"Journal of Allergy and Clinical Immunology: In Practice"},{"key":"2025090915511777700_b67-11_15092_si_cd_sonbrennan","article-title":"Asthma Is Different in Women","volume":"15","author":"Zein","year":"2016","journal-title":"Current Allergy and Asthma Reports"}],"container-title":["MIS Quarterly"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/misq.umn.edu\/misq\/article-pdf\/44\/1\/285\/633\/11_15092_si_cd_sonbrennan.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/misq.umn.edu\/misq\/article-pdf\/44\/1\/285\/633\/11_15092_si_cd_sonbrennan.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T19:51:36Z","timestamp":1757447496000},"score":1,"resource":{"primary":{"URL":"https:\/\/misq.umn.edu\/misq\/article\/44\/1\/285\/130\/A-Data-Analytics-Framework-for-Smart-Asthma"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,1]]},"references-count":67,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,3,1]]},"published-print":{"date-parts":[[2020,3,1]]}},"URL":"https:\/\/doi.org\/10.25300\/misq\/2020\/15092","relation":{},"ISSN":["0276-7783","2162-9730"],"issn-type":[{"value":"0276-7783","type":"print"},{"value":"2162-9730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,1]]}}}