{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T09:10:08Z","timestamp":1693818608185},"reference-count":0,"publisher":"Swiss Chemical Society","issue":"3","license":[{"start":{"date-parts":[[2015,3,25]],"date-time":"2015-03-25T00:00:00Z","timestamp":1427241600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chimia"],"abstract":"<jats:p>\n        Because of the widespread epigenetic changes ensuing from carcinogenesis, structural and chemical features of chromatin provide unique targets for developing safer and more effective anticancer drugs. Metal-based agents have a potential advantage over other small molecular species in\n that characteristics of coordination geometry, redox state and ligand exchange allow one to fine-tune reactivity and affinity properties in a distinct fashion. This intersection of chromatin biology and bioinorganic medicinal chemistry is the subject of multiple collaborations in and between Switzerland and Singapore.\n      <\/jats:p>","DOI":"10.2533\/chimia.2015.125","type":"journal-article","created":{"date-parts":[[2015,4,2]],"date-time":"2015-04-02T13:26:10Z","timestamp":1427981170000},"page":"125","source":"Crossref","is-referenced-by-count":5,"title":["Exposure to Metals Can Be Therapeutic"],"prefix":"10.2533","volume":"69","author":[{"given":"Curt A.","family":"Davey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1442","published-online":{"date-parts":[[2015,3,25]]},"container-title":["CHIMIA"],"original-title":[],"link":[{"URL":"https:\/\/www.chimia.ch\/chimia\/article\/download\/5714\/5004","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.chimia.ch\/chimia\/article\/download\/5714\/5004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T00:01:06Z","timestamp":1643328066000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.chimia.ch\/chimia\/article\/view\/5714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,25]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,3,1]]}},"URL":"https:\/\/doi.org\/10.2533\/chimia.2015.125","relation":{},"ISSN":["2673-2424","0009-4293"],"issn-type":[{"value":"2673-2424","type":"electronic"},{"value":"0009-4293","type":"print"}],"subject":[],"published":{"date-parts":[[2015,3,25]]}}}