{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:22:36Z","timestamp":1790490156604,"version":"4.1.0"},"reference-count":0,"publisher":"Swiss Chemical Society","issue":"12","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chimia"],"abstract":"<jats:p>\n        Buruli ulcer, classified as a neglected tropical disease by the World Health Organization, is caused by a mycobacterium which secretes a macrolidic exotoxin called mycolactone A\/B. In this article, several synthetic strategies for the preparation of this toxin are discussed, highlighting the importance of total synthesis for the exploration of biological mechanism underpinning relevant human diseases.\n      <\/jats:p>","DOI":"10.2533\/chimia.2017.836","type":"journal-article","created":{"date-parts":[[2017,12,31]],"date-time":"2017-12-31T04:32:23Z","timestamp":1514694743000},"page":"836","source":"Crossref","is-referenced-by-count":15,"title":["Total Syntheses of Mycolactone A\/B and its Analogues for the Exploration of the Biology of Buruli Ulcer"],"prefix":"10.2533","volume":"71","author":[{"given":"Sarah","family":"Saint-Auret","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Caroline","family":"Chany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Casarotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9dric","family":"Tresse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Parmentier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajer","family":"Abdelkafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Blanchard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1442","published-online":{"date-parts":[[2017,12,1]]},"container-title":["CHIMIA"],"original-title":[],"link":[{"URL":"https:\/\/chimia.ch\/chimia\/article\/download\/1691\/1011","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chimia.ch\/chimia\/article\/download\/1691\/1011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T12:43:05Z","timestamp":1643287385000},"score":1,"resource":{"primary":{"URL":"https:\/\/chimia.ch\/chimia\/article\/view\/1691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2017,12,1]]}},"URL":"https:\/\/doi.org\/10.2533\/chimia.2017.836","relation":{},"ISSN":["2673-2424","0009-4293"],"issn-type":[{"value":"2673-2424","type":"electronic"},{"value":"0009-4293","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12,1]]}}}