{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T07:18:51Z","timestamp":1787642331575,"version":"build-2736575974"},"reference-count":0,"publisher":"Swiss Chemical Society","issue":"7-8","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chimia"],"abstract":"<jats:p>Beyond emerging diagnostic applications, intact-virus detection is essential for understanding viral pathogenesis, host\u2013pathogen interactions, and vaccine development. This review highlights in a timeline-based perspective the progress in electrochemical detection of intact virions, focusing on single-virion sensitivity. By directly probing intact viral particles rather than molecular surrogates, nanopore-based resistive-pulse sensing and nano-impact electrochemistry have emerged as versatile virus-counting strategies, enabling selective identification, quantitation, and characterization of morphological and chemical heterogeneity without ensemble averaging. Their potential for calibration-free quantitation, integration with microfluidics, in situ preconcentration, advanced signal processing, and artificial intelligence positions electrochemical platforms as powerful tools for virus analysis.<\/jats:p>","DOI":"10.2533\/chimia.2026.487","type":"journal-article","created":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T22:34:34Z","timestamp":1787092474000},"page":"487-493","source":"Crossref","is-referenced-by-count":0,"title":["Electrochemical Detection Approaches Targeting Single Intact Virions"],"prefix":"10.2533","volume":"80","author":[{"given":"R\u00f3bert E.","family":"Gyurcs\u00e1nyi","sequence":"first","affiliation":[{"name":"Department of Inorganic and Analytical Chemistry, Faculty of Chemical Technology and Biotechnology, Budapest University ot Technology and Economics, Mu\u0308egyetem rkp. 3, Budapest, H-1111"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1442","published-online":{"date-parts":[[2026,8,19]]},"container-title":["CHIMIA"],"original-title":[],"link":[{"URL":"https:\/\/www.chimia.ch\/chimia\/article\/download\/2026_487\/2026_487","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.chimia.ch\/chimia\/article\/download\/2026_487\/2026_487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T06:21:47Z","timestamp":1787638907000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.chimia.ch\/chimia\/article\/view\/2026_487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,19]]},"references-count":0,"journal-issue":{"issue":"7-8","published-online":{"date-parts":[[2026,8,19]]}},"URL":"https:\/\/doi.org\/10.2533\/chimia.2026.487","relation":{},"ISSN":["2673-2424","0009-4293"],"issn-type":[{"value":"2673-2424","type":"electronic"},{"value":"0009-4293","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,19]]}}}