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The increase in the level of serum cobalamin occurs mainly in serious diseases that require early diagnosis: hemoblastosis, liver and kidney diseases, etc. This review presents data on the metabolism of vitamin B12 and the potential significance of increasing its level as a marker for the early diagnosis of these diseases.<\/jats:p>","DOI":"10.26442\/00403660.2019.08.000378","type":"journal-article","created":{"date-parts":[[2019,9,7]],"date-time":"2019-09-07T21:59:22Z","timestamp":1567893562000},"page":"160-167","source":"Crossref","is-referenced-by-count":5,"title":["Hypervitaminosis B12 - a new marker and predictor of prognostically unfavorable diseases"],"prefix":"10.26442","volume":"91","author":[{"given":"V I","family":"Podzolkov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N A","family":"Dragomiretskaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O Ts","family":"Dambaeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S T","family":"Auvinen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I D","family":"Medvedev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18344","published-online":{"date-parts":[[2019,8,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2007.07.007"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0045979"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2012.10.006"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.2001.00134.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2009.10.142"},{"key":"ref6","unstructured":"\u0412\u043e\u0440\u043e\u0431\u044c\u0435\u0432\u0430 \u041b.\u0418. \u041f\u0440\u043e\u043f\u0438\u043e\u043d\u043e\u0432\u043e\u043a\u0438\u0441\u043b\u044b\u0435 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0438 \u0438 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u0435 \u0432\u0438\u0442\u0430\u043c\u0438\u043d\u0430 \u041212. \u041c.: \u041c\u0413\u0423, 1986."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/45.4.671"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/18.7.1329"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2005.01.018"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2006.05.001"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1920.53.2.236"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1926.02680070016005"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/161638a0"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1126\/science.107.2781.396"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Castle W.B. 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