{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:32:40Z","timestamp":1740180760694,"version":"3.37.3"},"reference-count":14,"publisher":"Consilium Medicum","issue":"12","license":[{"start":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T00:00:00Z","timestamp":1607990400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>The current concepts of the short bowel syndrome and malabsorption after intestinal surgery are generally accepted, but do not fully reflect the patients condition, making it difficult to diagnose and treat it.\r\nAim.The purpose of the study is to analyze the clinical course of the patients after bowel resection, to create a classification based on the variants identified to allow for a differentiated treatment and to introduce the concept of the resected bowel syndrome.\r\nMaterials and methods.We observed 239 patients (96 men and 143 women) aged 18 to 80 who underwent intestinal resection for 1 month to 16 years (from 2002 to 2018). The 1st group included 96 patients with small bowel resection (40 men and 56 women). The 2nd group included 39 men and 58 women with small bowel resection, including the resection of the ileocecal valve and the right-hand side of the colon (n=97). The 3rd group included 17 men and 29 women with the resection of the right-hand side of the colon or colectomy (n=46). The survey included the NRS-2002 (Nutritional Risk Screening 2002) screening test to identify nutritional risk, a clinical assessment of the symptoms that occurred after the surgery, instrumental methods (esophagogastroduodenoscopy, colonoscopy with biopsy, ultrasound of the abdominal cavity organs and the kidneys, a plain radiography of the abdominal cavity organs, an X-ray examination of the small intestine and the intestinal passage), serum citrulline and short-chain fatty acids in faeces.\r\nResults.Based on the analysis of the clinical symptoms and the nutritional status of the patients, a new concept is proposed  the resected bowel syndrome  with two variants of its progression: either with or without the development of nutritional insufficiency of three types: the dehydration type, the protein-energy insufficiency type and a mixed type. Type 1 requires the use of antimicrobials with the control of SCFA concentrations in faeces. Type 2 requires the introduction of an optimal amount of easily digestible protein to correct protein-energy deficit. The 3rd (most severe) mixed type requires prescription of a parenteral nutrition component with the control of citrulline concentration in the blood serum.\r\nConclusion.The proposed concept  the resected bowel syndrome  makes it possible to improve its diagnosis, take into account the variants of its progression and allow for a differentiated treatment.<\/jats:p>","DOI":"10.26442\/00403660.2020.12.200452","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T09:12:59Z","timestamp":1612775579000},"page":"36-42","source":"Crossref","is-referenced-by-count":0,"title":["Resected bowel syndrome: clinical course and treatment options"],"prefix":"10.26442","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3107-3731","authenticated-orcid":false,"given":"I. E.","family":"Hatkov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2800-6503","authenticated-orcid":false,"given":"T. N.","family":"Kuzmina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7519-2041","authenticated-orcid":false,"given":"E. A.","family":"Sabelnikova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9782-4860","authenticated-orcid":false,"given":"A. I.","family":"Parfenov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18344","published-online":{"date-parts":[[2020,12,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.33.11.1493"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"\u0428\u0435\u0441\u0442\u043e\u043f\u0430\u043b\u043e\u0432 \u0410.\u0415., \u0421\u0432\u0438\u0440\u0438\u0434\u043e\u0432 \u0421.\u0412. \u0420\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438 \u0415\u0432\u0440\u043e\u043f\u0435\u0439\u0441\u043a\u043e\u0433\u043e \u043e\u0431\u0449\u0435\u0441\u0442\u0432\u0430 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043f\u0438\u0442\u0430\u043d\u0438\u044f \u0438 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0430 (ESPEN) \u043f\u043e \u043f\u0430\u0440\u0435\u043d\u0442\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u043c\u0443 \u043f\u0438\u0442\u0430\u043d\u0438\u044e \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0445. 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Moscow: M-Vesti, 2002 (In Russ.)]."}],"container-title":["Terapevticheskii arkhiv"],"original-title":[],"link":[{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/60252\/43414","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/60252\/43414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T20:13:30Z","timestamp":1634156010000},"score":1,"resource":{"primary":{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/view\/60252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,15]]},"references-count":14,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,12,15]]}},"URL":"https:\/\/doi.org\/10.26442\/00403660.2020.12.200452","relation":{},"ISSN":["2309-5342","0040-3660"],"issn-type":[{"type":"electronic","value":"2309-5342"},{"type":"print","value":"0040-3660"}],"subject":[],"published":{"date-parts":[[2020,12,15]]}}}