{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:25:56Z","timestamp":1791645956162,"version":"4.3.4"},"reference-count":38,"publisher":"Consilium Medicum","issue":"9","license":[{"start":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T00:00:00Z","timestamp":1631664000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>The paper summarizes the most important aspects of modern treatment of patients with pulmonary arterial hypertension (PAH): the goals of therapy are indicated, the issues of risk stratification of PAH progression\/mortality, the place of combination specific therapy and switching strategies are considered, as well as new promising approaches to therapy; features of the course of the new coronavirus infection COVID-19 in this category of patients are discussed.<\/jats:p>","DOI":"10.26442\/00403660.2021.09.201013","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T13:13:20Z","timestamp":1633871600000},"page":"1009-1017","source":"Crossref","is-referenced-by-count":5,"title":["Pulmonary arterial hypertension: achievements and realities of modern treatment, a look into the future"],"prefix":"10.26442","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9022-8097","authenticated-orcid":false,"given":"Tamila V.","family":"Martynyuk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9822-4357","authenticated-orcid":false,"given":"Irina E.","family":"Chazova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18344","published-online":{"date-parts":[[2021,9,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.38109\/2225-1685-2020-1-78-122"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01032-2015"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-115-5-343"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1460"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.26442\/00403660.2019.01.000024"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/6836973"},{"key":"ref7","unstructured":"\u041c\u0430\u0440\u0442\u044b\u043d\u044e\u043a \u0422.\u0412. \u041b\u0435\u0433\u043e\u0447\u043d\u0430\u044f \u0433\u0438\u043f\u0435\u0440\u0442\u0435\u043d\u0437\u0438\u044f: \u0414\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430 \u0438 \u043b\u0435\u0447\u0435\u043d\u0438\u0435. \u0421\u0435\u0440\u0438\u044f: \u0411\u0438\u0431\u043b\u0438\u043e\u0442\u0435\u043a\u0430 \u0424\u0413\u0411\u0423 \u00ab\u041d\u0418\u041c\u0426 \u043a\u0430\u0440\u0434\u0438\u043e\u043b\u043e\u0433\u0438\u0438\u00bb \u041c\u0438\u043d\u0437\u0434\u0440\u0430\u0432\u0430 \u0420\u043e\u0441\u0441\u0438\u0438. \u041c.: \u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e\u0435 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u043e\u043d\u043d\u043e\u0435 \u0430\u0433\u0435\u043d\u0442\u0441\u0442\u0432\u043e. 2018 [Martyniuk TV. Pulmonary Hypertension: Diagnosis and Treatment. Series: Library of the Federal State Budgetary Institution \u201cNIMC of Cardiology\u201d of the Ministry of Health of Russia. Moscow: Meditsinskoe informatsionnoe agentstvo. 2018 (in Russian)]."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.26442\/terarkh201890472-80"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.26442\/00403660.2020.09.000717"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-1004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-3023"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00740-2017"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.529800"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Gratsianskaia S, Valieva Z, Taran I, Martynyuk T. The role of the cardiopulmonary exercise testing in assessment of the severity of patients with PAH associated with congenital heart disease. Eur Respir J. 2019;54(Suppl. 63):PA4759","DOI":"10.1183\/13993003.congress-2019.PA4759"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx257"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00889-2017"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.10.026"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.18093\/0869-0189-2020-30-4-427-436"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.02.004"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2019.12.013"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1413687"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01889-2018"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2018.08.082"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.26442\/00403660.2020.12.000840"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Chin KM, Sitbon O, Doelberg M, et al. Efficacy and Safety of Initial Triple Oral Versus Initial Double Oral Combination Therapy in Patients with Newly Diagnosed Pulmonary Arterial Hypertension (PAH): Results of the Randomized Controlled TRITON Study. Am J of Respir and Crit Care Med 2020;201:A2928. Available at: https:\/\/www.atsjournals.org\/doi\/10.1164\/ajrccmconference.2020.201.1_MeetingAbstracts.A2928. Accessed: 20.08.2021.","DOI":"10.1164\/ajrccm-conference.2020.201.1_MeetingAbstracts.A2928"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02425-2016"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-018-0160-4"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30532-4"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01899-2018"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe2036314"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2024277"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-60761-500-2_28"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu035"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.079921"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.38109\/2225-1685-2020-2-54-60"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.87a.ccc021"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.202005-521OC"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1177\/2045894020922799"}],"container-title":["Terapevticheskii arkhiv"],"original-title":[],"link":[{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/82962\/63436","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/82962\/63436","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,13]],"date-time":"2021-10-13T03:42:05Z","timestamp":1634096525000},"score":1,"resource":{"primary":{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/view\/82962"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,15]]},"references-count":38,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2021,9,15]]}},"URL":"https:\/\/doi.org\/10.26442\/00403660.2021.09.201013","relation":{},"ISSN":["2309-5342","0040-3660"],"issn-type":[{"value":"2309-5342","type":"electronic"},{"value":"0040-3660","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9,15]]}}}