{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T15:03:16Z","timestamp":1743606196159,"version":"3.37.3"},"reference-count":20,"publisher":"Consilium Medicum","issue":"11","license":[{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>Aim. Evaluation of the clinical characteristics in patients with COVID-19.\r\nMaterials and methods. The article presents clinical and instrumental data of 1169 patients included in a single-center mixed study. Patients were tested for COVID-19 using polymerase chain reaction, computed tomography (CT), and antibody screening. Clinical history data were collected.\r\nResults. In patients with confirmed COVID-19, lung damage and a positive test for antibodies were observed in 75.5 and 45.2% of cases, respectively. The most common symptoms of COVID-19 were: fever (73.2%), weakness, (72.7%) dry cough (62.8%) and shortness of breath (55.4%). Patients with CT-visualized lung lesions were more likely to have clinical symptoms and elevated levels of antibodies. Patients with chronic diseases of the endocrine system, circulatory system, and respiratory system had a more severe course of the disease (CT-14: 91.296.3%) than patients without chronic diseases (CT-14: 85,1%).\r\nConclusion. We have compiled a clinical profile of patients with COVID-19 and highlighted the most significant clinical characteristics corresponding to a more severe course of the disease. Our data showed that patients with chronic diseases require a personalized approach and the development of specific criteria for the diagnosis and treatment of COVID-19.<\/jats:p>","DOI":"10.26442\/00403660.2021.11.201191","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T09:54:04Z","timestamp":1643795644000},"page":"1283-1289","source":"Crossref","is-referenced-by-count":3,"title":["Clinical portrait of a patient with COVID-19. The experience of a multidisciplinary clinic"],"prefix":"10.26442","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8198-9313","authenticated-orcid":false,"given":"Gulsara E.","family":"Baimakanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4088-8118","authenticated-orcid":false,"given":"Igor E.","family":"Khatkov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9673-1067","authenticated-orcid":false,"given":"Galina A.","family":"Dudina.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7753-3698","authenticated-orcid":false,"given":"Anzhelika S.","family":"Chegodar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3184-5439","authenticated-orcid":false,"given":"Konstantin A.","family":"Rumyantsev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3767-9339","authenticated-orcid":false,"given":"Filipp S.","family":"Sviridov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9664-0931","authenticated-orcid":false,"given":"Alena V","family":"Osipova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3573-8342","authenticated-orcid":false,"given":"Anastasiia M.","family":"Danishevich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina K.","family":"Noskova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0223-2302","authenticated-orcid":false,"given":"Evgeniia S.","family":"Pinashina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9007-7911","authenticated-orcid":false,"given":"Nataliia V.","family":"Orlova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2049-4146","authenticated-orcid":false,"given":"Viacheslav M.","family":"Slezinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6127-1723","authenticated-orcid":false,"given":"Marina E.","family":"Chernova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1989-0333","authenticated-orcid":false,"given":"Karina A.","family":"Tovstyko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3119-7673","authenticated-orcid":false,"given":"Natalia A.","family":"Bodunova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18344","published-online":{"date-parts":[[2021,11,15]]},"reference":[{"unstructured":"WHO Director-General\u2019s opening remarks at the media briefing on COVID-19 \u2013 11 March 2020. 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