{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T01:27:39Z","timestamp":1793582859218,"version":"4.5.0"},"reference-count":38,"publisher":"Consilium Medicum","issue":"1","license":[{"start":{"date-parts":[[2022,1,15]],"date-time":"2022-01-15T00:00:00Z","timestamp":1642204800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>Background. Recently, there has been an increase in the prevalence of gastroesophageal reflux disease (GERD) in Northern Europe, North America and East Asia. However data on GERD prevalence in Russian population are very limited.\r\nAim. To determine the prevalence of GERD among the population of Russia, the clinical spectrum of GERD symptoms, the main drugs used for GERD treatment, and the rate of their administration.\r\nMaterials and methods. The study was conducted from November 2015 to January 2017 in 8 cities of Russia. A survey of patients over the age of 18 years old visiting outpatient medical institutions for any reason, including patients without gastrointestinal complaints was carried out using a short version of the Mayo Clinic questionnaire.\r\nResults. In total, 6132 questionnaires of patients aged 1890 years were analyzed [2456 men (40.1%) and 3676 women (59.9%), mean age  46.615.4 years]. The GERD prevalence among the interviewed patients was 34.2%. The incidence of GERD increased depending on body mass index and the age of the patients. Medications used by the patients for heartburn relief included proton pump inhibitors  59.96%, antacids  67.92%, H2-histamine receptor blockers  11.42%, alginates  18.41% of patients.\r\nConclusion. The results of this study indicate a high prevalence of GERD among residents of Russian cities applying for primary health care (34.2%). In comparison with previous studies, an increase in the proportion of GERD patients taking proton pump inhibitors was noted; in most cases the regimen of their intake was in accordance with the recommendations.<\/jats:p>","DOI":"10.26442\/00403660.2022.01.201322","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T16:54:22Z","timestamp":1647536062000},"page":"48-56","source":"Crossref","is-referenced-by-count":28,"title":["Multicenter study of gastroesophageal reflux disease symptoms prevalence in outpatients in Russia"],"prefix":"10.26442","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2815-3992","authenticated-orcid":false,"given":"Dmitry S.","family":"Bordin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1509-6776","authenticated-orcid":false,"given":"Rustam \u0410.","family":"Abdulkhakov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5156-2842","authenticated-orcid":false,"given":"Marina F.","family":"Osipenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7675-6889","authenticated-orcid":false,"given":"Alla V.","family":"Solovyeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9542-3580","authenticated-orcid":false,"given":"Sayar R.","family":"Abdulkhakov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5799-2504","authenticated-orcid":false,"given":"Nikolay P.","family":"Kirilenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3402-1128","authenticated-orcid":false,"given":"Mikhail A.","family":"Butov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9648-2603","authenticated-orcid":false,"given":"Olga I.","family":"Berezina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3397-9748","authenticated-orcid":false,"given":"Elen R.","family":"Valitova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5985-3089","authenticated-orcid":false,"given":"Dilyara D.","family":"Safina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-5848","authenticated-orcid":false,"given":"Ilmira M.","family":"Alieva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6581-7017","authenticated-orcid":false,"given":"Maria A.","family":"Livzan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5922-2271","authenticated-orcid":false,"given":"Aiman S.","family":"Sarsenbaeva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4054-9180","authenticated-orcid":false,"given":"Galina N.","family":"Tarasova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6479-9515","authenticated-orcid":false,"given":"Yulia V.","family":"Embutnieks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3978-0430","authenticated-orcid":false,"given":"Indira R.","family":"Mubarakshina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilshat Kh.","family":"Khayrullin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alla G.","family":"Kononova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9223-0457","authenticated-orcid":false,"given":"Sergey V.","family":"Kolbasnikov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6114-564X","authenticated-orcid":false,"given":"Igor V.","family":"Maev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18344","published-online":{"date-parts":[[2022,1,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00630.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.444"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.08.044"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2015.02.021"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.87a.19114"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.2008.s1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0025-6196(12)62245-9"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2003.01769.x"},{"key":"ref9","unstructured":"Haque M, Wyeth JW, Stace NH, et al. Prevalence, severity and associated features of gastro-oesophageal reflux and dyspepsia: a population-based study. N Z Med J. 2000;113:178-81."},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200203000-00012"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9270(01)02580-1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2007.01475.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-304269"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-62795-1"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2013.11.006"},{"key":"ref16","unstructured":"\u041b\u0430\u0437\u0435\u0431\u043d\u0438\u043a \u041b.\u0411., \u041c\u0430\u0448\u0430\u0440\u043e\u0432\u0430 \u0410.\u0410., \u0411\u043e\u0440\u0434\u0438\u043d \u0414.\u0421., \u0438 \u0434\u0440. \u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u041c\u043d\u043e\u0433\u043e\u0446\u0435\u043d\u0442\u0440\u043e\u0432\u043e\u0433\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u00ab\u042d\u043f\u0438\u0434\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0413\u0430\u0441\u0442\u0440\u043e\u044d\u0437\u043e\u0444\u0430\u0433\u0435\u0430\u043b\u044c\u043d\u043e\u0439 \u0420\u0415\u0444\u043b\u044e\u043a\u0441\u043d\u043e\u0439 \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u0432 \u0420\u043e\u0441\u0441\u0438\u0438\u00bb (\u041c\u042d\u0413\u0420\u0415). \u0422\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0430\u0440\u0445\u0438\u0432. 2011;83(1):45-50 [Lazebnik LB, Masharova AA, Bordin DS, et al. Results of a multicenter trial \"Epidemiology of Gastroesophageal Reflux Disease in Russia\" (MEGRE). Terapevticheskii Arkhiv (Ter. Arkh.). 2011;83(1):45-50 (in Russian)]."},{"key":"ref17","unstructured":"\u0418\u0441\u0430\u043a\u043e\u0432 \u0412.\u0410., \u041c\u043e\u0440\u043e\u0437\u043e\u0432 \u0421.\u0412., \u0421\u0442\u0430\u0432\u0440\u0430\u043a\u0438 \u0415.\u0421., \u041a\u043e\u043c\u0430\u0440\u043e\u0432 \u0420.\u0421. \u0410\u043d\u0430\u043b\u0438\u0437 \u0420\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u0418\u0437\u0436\u043e\u0433\u0438: \u043d\u0410\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0435 \u044d\u043f\u0438\u0414\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u041d\u0438\u0435 \u0432\u0437\u0440\u043e\u0441\u043b\u043e\u0433\u043e \u0433\u043e\u0440\u043e\u0434\u0441\u043a\u043e\u0433\u043e \u043d\u0410\u0441\u0435\u043b\u0435\u043d\u0438\u044f (\u0410\u0420\u0418\u0410\u0414\u041d\u0410). \u042d\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u0430\u044f \u0438 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0433\u0430\u0441\u0442\u0440\u043e\u044d\u043d\u0442\u0435\u0440\u043e\u043b\u043e\u0433\u0438\u044f. 2008;1:20-30 [Isakov VA, Morozov SV, Stavraki ES, Komarov RM. Heartburn prevalence analysis: national epidemiologic examination of adult urban population (ARIADNA). Experimental & Clinical Gastroenterology. 2008;1:20-30 (in Russian)]."},{"key":"ref18","unstructured":"\u0410\u0431\u0434\u0443\u043b\u0445\u0430\u043a\u043e\u0432 \u0421.\u0420., \u0410\u0431\u0434\u0443\u043b\u0445\u0430\u043a\u043e\u0432 \u0420.\u0410. \u0420\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043e\u0432 \u0433\u0430\u0441\u0442\u0440\u043e\u044d\u0437\u043e\u0444\u0430\u0433\u0435\u0430\u043b\u044c\u043d\u043e\u0439 \u0440\u0435\u0444\u043b\u044e\u043a\u0441\u043d\u043e\u0439 \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u0432 \u0433. \u041a\u0430\u0437\u0430\u043d\u0438. \u041f\u0440\u0430\u043a\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0430. 2011;1:82-5 [Abdulhakov SR, Abdulhakov RA. Prevalence of symptoms of gastroesophageal reflux disease in Kazan. Practical Medicine. 2011;1:82-5 (in Russian)]."},{"key":"ref19","unstructured":"\u041a\u0443\u0440\u0438\u043b\u043e\u0432\u0438\u0447 \u0421.\u0410., \u0420\u0435\u0448\u0435\u0442\u043d\u0438\u043a\u043e\u0432 \u041e.\u0412. \u042d\u043f\u0438\u0434\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u043e\u0440\u0433\u0430\u043d\u043e\u0432 \u043f\u0438\u0449\u0435\u0432\u0430\u0440\u0435\u043d\u0438\u044f \u0432 \u0417\u0430\u043f\u0430\u0434\u043d\u043e\u0439 \u0421\u0438\u0431\u0438\u0440\u0438. \u041d\u043e\u0432\u043e\u0441\u0438\u0431\u0438\u0440\u0441\u043a: \u041d\u043e\u0432\u043e\u0441\u0438\u0431\u0438\u0440\u0441\u043a\u0438\u0439 \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0439 \u0438\u043d\u0441\u0442\u0438\u0442\u0443\u0442; 2000 [Kurilovich SA, Reshetnikov VO. Epidemiology of digestive diseases in Western Siberia. Novosibirsk: Novosibirsk State Medical University; 2000 (in Russian)]."},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/dote.12310"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2010.09.009"},{"key":"ref22","unstructured":"\u0420\u0435\u0448\u0435\u0442\u043d\u0438\u043a\u043e\u0432 \u041e.\u0412., \u041a\u0443\u0440\u0438\u043b\u043e\u0432\u0438\u0447 \u0421.\u0410., \u0414\u0435\u043d\u0438\u0441\u043e\u0432\u0430 \u0414.\u0412. \u0421\u0438\u043c\u043f\u0442\u043e\u043c\u044b \u0433\u0430\u0441\u0442\u0440\u043e\u044d\u0437\u043e\u0444\u0430\u0433\u0435\u0430\u043b\u044c\u043d\u043e\u0439 \u0440\u0435\u0444\u043b\u044e\u043a\u0441\u043d\u043e\u0439 \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u0438 \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0435 \u0444\u0430\u043a\u0442\u043e\u0440\u044b \u0443 \u043f\u043e\u0434\u0440\u043e\u0441\u0442\u043a\u043e\u0432: \u043f\u043e\u043f\u0443\u043b\u044f\u0446\u0438\u043e\u043d\u043d\u043e\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435. \u042d\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u0430\u044f \u0438 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0433\u0430\u0441\u0442\u0440\u043e\u044d\u043d\u0442\u0435\u0440\u043e\u043b\u043e\u0433\u0438\u044f. 2013;12:8-14. [Reshetnikov OV, Kurilovich SA, Denisova DV. Symptoms of gastroesophageal reflux disease and associated factors in adolescents: population survey. Experimental & Clinical Gastroenterology. 2013;12:8-14 (in Russian)]."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.41065.x"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Bor S, Kitapcioglu G, Kasap E, Ilter T. The prevalence of gastroesophageal reflux disease in Turkey: lessons from a Helicobacter pylori prevalent country. J Clin Gastroenterol. 2006;40:S182.","DOI":"10.1097\/00004836-200609001-00057"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(97)70025-8"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04396.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2000.00884.x"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-300715"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2007.05045.x"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2005.10.011"},{"key":"ref31","unstructured":"Nouraie M, Razjouyan H, Assady M, et al. Epidemiology of gastroesophageal reflux symptoms in Tehran, Iran: a population-based telephone survey. Arch Iran Med. 2007;10(3):289-94."},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.02727.x"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v10.i11.1647"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2010.04396.x"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2003.01769.x"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.33978\/2307-3586-2021-17-4-12-20"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.22416\/1382-4376-2020-30-4-70-97"},{"key":"ref38","unstructured":"\u041b\u0430\u0437\u0435\u0431\u043d\u0438\u043a \u041b.\u0411., \u0411\u043e\u0440\u0434\u0438\u043d \u0414.\u0421., \u0410\u0431\u0434\u0443\u043b\u0445\u0430\u043a\u043e\u0432 \u0420.\u0410., \u0438 \u0434\u0440. \u042d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u043f\u0430\u043d\u0442\u043e\u043f\u0440\u0430\u0437\u043e\u043b\u0430 (\u041d\u043e\u043b\u044c\u043f\u0430\u0437\u044b) \u043f\u0440\u0438 \u043e\u0434\u043d\u043e\u043a\u0440\u0430\u0442\u043d\u043e\u043c \u0443\u0442\u0440\u0435\u043d\u043d\u0435\u043c \u043f\u0440\u0438\u0435\u043c\u0435 40 \u043c\u0433 \u0443 \u0431\u043e\u043b\u044c\u043d\u044b\u0445 \u0433\u0430\u0441\u0442\u0440\u043e\u044d\u0437\u043e\u0444\u0430\u0433\u0435\u0430\u043b\u044c\u043d\u043e\u0439 \u0440\u0435\u0444\u043b\u044e\u043a\u0441\u043d\u043e\u0439 \u0431\u043e\u043b\u0435\u0437\u043d\u044c\u044e: \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 PAN-STAR. Consilium Medicum. 2013;15(8):24-9 [Lazebnik LB, Bordin DS, Abdulkhakov RA, et al. The efficacy of pantoprazole (Nolpaza) in a single morning dose of 40 mg in patients with gastroesophageal reflux disease: PAN-STAR study. Consilium Medicum. 2013;15(8):24-9 (in Russian)]."}],"container-title":["Terapevticheskii arkhiv"],"original-title":[],"link":[{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/104758\/79174","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/104758\/79174","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T16:59:17Z","timestamp":1647536357000},"score":1,"resource":{"primary":{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/view\/104758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,15]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,15]]}},"URL":"https:\/\/doi.org\/10.26442\/00403660.2022.01.201322","relation":{},"ISSN":["2309-5342","0040-3660"],"issn-type":[{"value":"2309-5342","type":"electronic"},{"value":"0040-3660","type":"print"}],"subject":[],"published":{"date-parts":[[2022,1,15]]}}}