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Developing in conditions of visceral obesity, insulin resistance, dyslipidemia and systemic inflammation are one of the key components of the pathogenesis of type 2 diabetes mellitus, cardiovascular diseases, non-alcoholic fatty liver and pancreas disease, polycystic ovary disease, some forms of cancer (breast cancer, endometrial cancer, colonic and direct intestines). At the same time, the pathogenetic role of adipose tissue is not limited to its participation in the formation of the cardiometabolic continuum and oncogenesis. The most important role of metabolically active fat in the pathogenesis of many respiratory diseases is known, including bronchial asthma, obstructive sleep apnea and pulmonary hypertension. This paper presents an overview of current data on immunological, pathophysiological and clinical features of the phenotype of the combination of respiratory diseases with overweight and obesity.<\/jats:p>","DOI":"10.26442\/00403660.2022.03.201412","type":"journal-article","created":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T13:05:02Z","timestamp":1650373502000},"page":"442-447","source":"Crossref","is-referenced-by-count":5,"title":["Respiratory diseases and obesity: special phenotype or independent events: Review"],"prefix":"10.26442","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9146-0904","authenticated-orcid":false,"given":"Evgeniy I.","family":"Shchepikhin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1908-5601","authenticated-orcid":false,"given":"Evgene I.","family":"Shmelev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7155-5730","authenticated-orcid":false,"given":"Anna S.","family":"Zaytseva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18344","published-online":{"date-parts":[[2022,3,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32129-3"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"\u041d\u0435\u0434\u043e\u0433\u043e\u0434\u0430 \u0421.\u0412., \u0411\u0430\u0440\u044b\u043a\u0438\u043d\u0430 \u0418.\u041d., \u0421\u0430\u043b\u0430\u0441\u044e\u043a \u0410.\u0421. \u041d\u0430\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438 \u043f\u043e \u043e\u0436\u0438\u0440\u0435\u043d\u0438\u044e: \u043a\u043e\u043d\u0446\u0435\u043f\u0446\u0438\u044f \u0438 \u043f\u0435\u0440\u0441\u043f\u0435\u043a\u0442\u0438\u0432\u044b. \u0412\u0435\u0441\u0442\u043d\u0438\u043a \u0412\u043e\u043b\u0433\u043e\u0433\u0440\u0430\u0434\u0441\u043a\u043e\u0433\u043e \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0433\u043e \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e\u0433\u043e \u0443\u043d\u0438\u0432\u0435\u0440\u0441\u0438\u0442\u0435\u0442\u0430. 2017;1(61):134-40 [Nedogoda SV, Barykina IN, Salasyuk AS. 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