{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T23:33:40Z","timestamp":1771544020755,"version":"3.50.1"},"reference-count":22,"publisher":"Consilium Medicum","issue":"5","license":[{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>Background. Psoriatic arthritis (PsA) is a complex immune-mediated disease in which a third of patients with psoriasis (PsO) have a inflammatory lesion of both the musculoskeletal system (peripheral joints and axial structures) and extra-articular manifestations (dactylitis, enthesitis, nail PsO, uveitis and inflammatory bowel disease).\r\nAim. To assess the burden of PsA progression in real practice according to the Russian register of PsA patients.\r\nMaterials and methods. Seven hundred thirty seven  M\/F=350 (47.5%)\/387 (52.5%)  patients with PsA from the Russian register of PsA patients were included. Mean age 47.412.7 yrs., duration of PsO 200.6158.9 mo., PsA  79.681.9 mo. All patients were divided into 2 groups by PsA duration: 1st gr 36 mo  288 (39.1%) and 2nd gr 36 mo  449 (60.9%). All patients underwent standard clinical examination of PsA activity. Tender (68) and swelling (66) joint count (TJC, SJC), DAPSA, LEI, tenderness of the plantar fascia, PsO BSA (%), PASI, HAQ-DI, PsAID-12, BMI (kg\/m2), ESR (mm\/h), CRP (mg\/l) and comorbidities by ICD-10 were evaluated. Parametric and non-parametric methods of statistical analysis were used. All p0.05 were considered to indicate statistical significance.\r\nResults. In patients with PsA duration 36 mo we found significant prevalence of erosions by X-Ray, axial PsA, BMI30 kg\/m2, HAQ-DI1, PsAID-124, arterial hypertension, metabolic syndrome and overall comorbidity (p0.05). There were no significant differences between groups in PsO severity by BSA3%, PASI1, LEI1, TJC, SJC, dactylitis, ESR30 mm\/h, CRP10 mg\/l, DAPSA, diabetes mellitus, hyperlipidemia, coronary heart disease and liver damage (p0.05).\r\n\u0421onclusion. Long-standing stage PsA is associated with erosions, axial PsA, worst health related quality of life, functional disability and increased cardio-metabolic disorders and overall comorbidity. Our results support the idea to start bDMARDs at early stage of PsA, it can improve better outcomes.<\/jats:p>","DOI":"10.26442\/00403660.2022.05.201506","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T16:33:23Z","timestamp":1655483603000},"page":"622-627","source":"Crossref","is-referenced-by-count":8,"title":["The burden of progression of psoriatic arthritis. All-Russian register data"],"prefix":"10.26442","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5968-2403","authenticated-orcid":false,"given":"Yulia L.","family":"Korsakova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6875-4552","authenticated-orcid":false,"given":"Elena Yu.","family":"Loginova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0579-1131","authenticated-orcid":false,"given":"Tatiana V.","family":"Korotaeva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5015-7143","authenticated-orcid":false,"given":"Elena E.","family":"Gubar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4285-0869","authenticated-orcid":false,"given":"Svetlana I.","family":"Glukhova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2153-5429","authenticated-orcid":false,"given":"Elizaveta A.","family":"Vasilenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1598-8360","authenticated-orcid":false,"given":"Evgeny L.","family":"Nasonov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"18344","published-online":{"date-parts":[[2022,6,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1505557"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa062"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1136\/ARD.2004.032482"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-2043-3"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.150165"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/RMDOPEN-2021-001671"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Mease PJ, Palmer JB, Liu M, et al. Influence of axial involvement on clinical characteristics of psoriatic arthritis: analysis from the Corrona Psoriatic Arthritis\/Spondyloarthritis Registry. J Rheumatol. 2018;45(10):1389-96. DOI:10.3899\/ jrheum.171094","DOI":"10.3899\/jrheum.171094"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207507"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.091059"},{"key":"ref10","unstructured":"Haroon M, Winchester R, Giles JT. et al. Clinical and genetic associations of radiographic sacroiliitis and its different patterns in psoriatic arthritis. Clin Exp Rheumatol. 2017;35(2):270-6."},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.47360\/1995-4484-2020-401-406"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2020-217159"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/ACR.23249"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.47360\/1995-4484-2020-695-700"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/key417"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-1810-5"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-220263"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.26442\/00403660.2021.05.200789"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3899\/JRHEUM.210159"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.180670"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-219961"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2016.04.018"}],"container-title":["Terapevticheskii arkhiv"],"original-title":[],"link":[{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/108778\/82891","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/viewFile\/108778\/82891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T16:33:41Z","timestamp":1655483621000},"score":1,"resource":{"primary":{"URL":"https:\/\/ter-arkhiv.ru\/0040-3660\/article\/view\/108778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,17]]},"references-count":22,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,6,17]]}},"URL":"https:\/\/doi.org\/10.26442\/00403660.2022.05.201506","relation":{},"ISSN":["2309-5342","0040-3660"],"issn-type":[{"value":"2309-5342","type":"electronic"},{"value":"0040-3660","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6,17]]}}}