{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:05:22Z","timestamp":1777946722418,"version":"3.51.4"},"reference-count":20,"publisher":"Consilium Medicum","issue":"4","license":[{"start":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:00:00Z","timestamp":1777680000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Terapevticheskii arkhiv"],"abstract":"<jats:p>Neurofibromatosis (NF) is a hereditary disease characterized by the formation and growth of benign tumors of neuroectodermal origin. There are three main nosological forms: NF1, NF2, NF3. It is believed that the disease debuts in childhood and significantly reduces the life expectancy of patients. The main cause of death in middle age are cardiovascular diseases and malignant neoplasms. There are isolated publications on NF in patients over 60 years old. The relationship between NF and cardiorenal syndrome has not been sufficiently studied. The development of vasculitis with vasculopathy is described, which leads to narrowing and occlusion of the coronary, renal, cerebral and other arteries. The article presents a description of an 85-year-old patient with NF and the development of cardiorenal syndrome.<\/jats:p>","DOI":"10.26442\/00403660.2026.04.203586","type":"journal-article","created":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T20:12:58Z","timestamp":1777752778000},"page":"243-250","source":"Crossref","is-referenced-by-count":0,"title":["Cardiorenal syndrome in an 85-year-old patient with neurofibromatosis. 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