{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:42:25Z","timestamp":1790476945930,"version":"4.1.0"},"reference-count":100,"publisher":"Life Science Alliance, LLC","issue":"11","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["JP24590349, JP15K08265, JP16KK0202"],"award-info":[{"award-number":["JP24590349, JP15K08265, JP16KK0202"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["JP20KK0371"],"award-info":[{"award-number":["JP20KK0371"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020964","name":"MEXT | JST | Fusion Oriented REsearch for disruptive Science and Technology","doi-asserted-by":"publisher","award":["JPMJFR2255"],"award-info":[{"award-number":["JPMJFR2255"]}],"id":[{"id":"10.13039\/501100020964","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006680","name":"Takeda Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006680","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007434","name":"Suzuken Memorial Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007434","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009578","name":"Mizutani Foundation for Glycoscience","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009578","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["25D001 J-GlycoNet"],"award-info":[{"award-number":["25D001 J-GlycoNet"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["life-science-alliance.org"],"crossmark-restriction":true},"short-container-title":["Life Sci. Alliance"],"accepted":{"date-parts":[[2025,8,20]]},"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>\n                    Spinal cord injury (SCI) damages neural circuits and triggers pro-inflammatory responses, resulting in locomotor impairment. The carbohydrate sulfotransferases GlcNAc6ST1 and GlcNAc6ST4 modulate the function of blood monocytes and microglia. However, their specific roles and enzymatic relationships in neuroinflammation and functional recovery after SCI remain unclear. In this study, we demonstrate that mice deficient in both GlcNAc6ST1 and GlcNAc6ST4 (DKO) exhibit improved locomotor recovery compared with mice with a single deficiency. DKO mice exhibit reduced levels of monocytes and activated macrophages\/microglia at the injury site alongside increased serotonergic neural fibers, indicating enhanced neural plasticity. RNA sequencing reveals down-regulation of collagen I genes and up-regulation of genes encoding synaptic membrane components in the injured DKO spinal cord. In addition, GALAXY glycomic analysis shows an absence of GlcNAc-6-sulfated\n                    <jats:italic>N<\/jats:italic>\n                    -glycans in the DKO spinal cord. These results suggest that GlcNAc6ST1 and GlcNAc6ST4 play complementary roles in promoting detrimental inflammatory responses post-SCI. Targeting these sulfotransferases could offer a novel therapeutic strategy to improve locomotor recovery after SCI.\n                  <\/jats:p>","DOI":"10.26508\/lsa.202503469","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T06:21:17Z","timestamp":1755757277000},"page":"e202503469","update-policy":"https:\/\/doi.org\/10.26508\/lsa.crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Enhanced locomotor recovery in mice lacking GlcNAc6ST1 and GlcNAc6ST4 following spinal cord injury"],"prefix":"10.26508","volume":"8","author":[{"given":"Masayoshi","family":"Morozumi","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Biochemistry, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]},{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Orthopedic Surgery, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoya","family":"Ozaki","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Biochemistry, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3056-8310","authenticated-orcid":true,"given":"Kazuchika","family":"Nishitsuji","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/005qv5373","id-type":"ROR","asserted-by":"publisher"}],"name":"Wakayama Medical University","place":[", Wakayama, Japan"]},{"id":[{"id":"https:\/\/ror.org\/02kzqn938","id-type":"ROR","asserted-by":"publisher"}],"name":"University Lille","place":[", CNRS, UMR 8576-UGSF- Unit\u00e9 de Glycobiologie Structurale et Fonctionnelle, Lille, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiko","family":"Takeda-Uchimura","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/02kzqn938","id-type":"ROR","asserted-by":"publisher"}],"name":"University Lille","place":[", CNRS, UMR 8576-UGSF- Unit\u00e9 de Glycobiologie Structurale et Fonctionnelle, Lille, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiyuki","family":"Matsumoto","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Biochemistry, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]},{"id":[{"id":"https:\/\/ror.org\/01z9vrt66","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Orthopedic Surgery, Okazaki City Hospital","place":[", Aichi, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadayuki","family":"Ito","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Biochemistry, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]},{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Orthopedic Surgery, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiro","family":"Imagama","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Orthopedic Surgery, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Ishiguro","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Orthopedic Surgery, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9296-0225","authenticated-orcid":true,"given":"Hirokazu","family":"Yagi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04wn7wc95","id-type":"ROR","asserted-by":"publisher"}],"name":"Graduate School of Pharmaceutical Sciences, Nagoya City University","place":[", Nagoya, Japan"]},{"id":[{"id":"https:\/\/ror.org\/055n47h92","id-type":"ROR","asserted-by":"publisher"}],"name":"Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences","place":[", Okazaki, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7187-9612","authenticated-orcid":true,"given":"Koichi","family":"Kato","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04wn7wc95","id-type":"ROR","asserted-by":"publisher"}],"name":"Graduate School of Pharmaceutical Sciences, Nagoya City University","place":[", Nagoya, Japan"]},{"id":[{"id":"https:\/\/ror.org\/055n47h92","id-type":"ROR","asserted-by":"publisher"}],"name":"Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences","place":[", Okazaki, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoya O","family":"Akama","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Kansai Medical University, Osaka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Kosugi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Nephrology, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichi","family":"Maruyama","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Nephrology, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Kadomatsu","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Biochemistry, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]},{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Institute for Glyco-core Research (iGCORE), Nagoya University","place":[", Nagoya, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6245-701X","authenticated-orcid":true,"given":"Steven D","family":"Rosen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/043mz5j54","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Anatomy, University of California, San Francisco","place":[", CA, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda J","family":"Noble-Haeusslein","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Physical Therapy and Rehabilitation Science, University of California, San Francisco, CA, USA"},{"name":"Department of Psychology and Neurology, The Dell Medical School, University of Texas, Austin, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3009-248X","authenticated-orcid":true,"given":"Kenji","family":"Uchimura","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04chrp450","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Biochemistry, Nagoya University","place":["Graduate School of Medicine, Nagoya, Japan"]},{"id":[{"id":"https:\/\/ror.org\/02kzqn938","id-type":"ROR","asserted-by":"publisher"}],"name":"University Lille","place":[", CNRS, UMR 8576-UGSF- Unit\u00e9 de Glycobiologie Structurale et Fonctionnelle, Lille, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"12380","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"2025110308151212000_8.11.e202503469.1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-017-0033-9"},{"key":"2025110308151212000_8.11.e202503469.2","doi-asserted-by":"publisher","DOI":"10.1038\/nature10199"},{"key":"2025110308151212000_8.11.e202503469.3","doi-asserted-by":"publisher","DOI":"10.1038\/nature17623"},{"key":"2025110308151212000_8.11.e202503469.4","doi-asserted-by":"publisher","DOI":"10.1038\/nn1195"},{"key":"2025110308151212000_8.11.e202503469.5","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2006.23.635"},{"key":"2025110308151212000_8.11.e202503469.6","doi-asserted-by":"publisher","DOI":"10.1101\/2024.05.07.592424"},{"key":"2025110308151212000_8.11.e202503469.7","doi-asserted-by":"publisher","DOI":"10.1038\/416636a"},{"key":"2025110308151212000_8.11.e202503469.8","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31797-0"},{"key":"2025110308151212000_8.11.e202503469.9","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.9.5367"},{"key":"2025110308151212000_8.11.e202503469.10","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.4735677"},{"key":"2025110308151212000_8.11.e202503469.11","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008942828960"},{"key":"2025110308151212000_8.11.e202503469.12","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3053"},{"key":"2025110308151212000_8.11.e202503469.13","doi-asserted-by":"publisher","DOI":"10.1038\/37776"},{"key":"2025110308151212000_8.11.e202503469.14","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwf080"},{"key":"2025110308151212000_8.11.e202503469.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.02.004"},{"key":"2025110308151212000_8.11.e202503469.16","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3070"},{"key":"2025110308151212000_8.11.e202503469.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2007.06.009"},{"key":"2025110308151212000_8.11.e202503469.18","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-020-00770-9"},{"key":"2025110308151212000_8.11.e202503469.19","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-102419-035900"},{"key":"2025110308151212000_8.11.e202503469.20","doi-asserted-by":"publisher","DOI":"10.1038\/srep41008"},{"key":"2025110308151212000_8.11.e202503469.21","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2015.04.006"},{"key":"2025110308151212000_8.11.e202503469.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2014.01.013"},{"key":"2025110308151212000_8.11.e202503469.23","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pbr.2015.02.001"},{"key":"2025110308151212000_8.11.e202503469.24","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1737-11.2011"},{"key":"2025110308151212000_8.11.e202503469.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.07.016"},{"key":"2025110308151212000_8.11.e202503469.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.12.023"},{"key":"2025110308151212000_8.11.e202503469.27","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20934"},{"key":"2025110308151212000_8.11.e202503469.28","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2377"},{"key":"2025110308151212000_8.11.e202503469.29","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2014.00151"},{"key":"2025110308151212000_8.11.e202503469.30","doi-asserted-by":"publisher","DOI":"10.1126\/science.1203165"},{"key":"2025110308151212000_8.11.e202503469.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e18339"},{"key":"2025110308151212000_8.11.e202503469.32","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4354"},{"key":"2025110308151212000_8.11.e202503469.33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0605441103"},{"key":"2025110308151212000_8.11.e202503469.34","doi-asserted-by":"publisher","DOI":"10.3390\/biology9020029"},{"key":"2025110308151212000_8.11.e202503469.35","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2017.06.007"},{"key":"2025110308151212000_8.11.e202503469.36","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2488-08.2008"},{"key":"2025110308151212000_8.11.e202503469.37","doi-asserted-by":"publisher","DOI":"10.1369\/0022155413511619"},{"key":"2025110308151212000_8.11.e202503469.38","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2570-09.2010"},{"key":"2025110308151212000_8.11.e202503469.39","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-11-04611.2002"},{"key":"2025110308151212000_8.11.e202503469.40","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4886(03)00087-6"},{"key":"2025110308151212000_8.11.e202503469.41","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3257-09.2009"},{"key":"2025110308151212000_8.11.e202503469.42","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aav5086"},{"key":"2025110308151212000_8.11.e202503469.43","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.07.027"},{"key":"2025110308151212000_8.11.e202503469.44","doi-asserted-by":"publisher","DOI":"10.1038\/nature13974"},{"key":"2025110308151212000_8.11.e202503469.45","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00150"},{"key":"2025110308151212000_8.11.e202503469.46","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2795-6"},{"key":"2025110308151212000_8.11.e202503469.47","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021499"},{"key":"2025110308151212000_8.11.e202503469.48","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2020.08.012"},{"key":"2025110308151212000_8.11.e202503469.49","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2013.00034"},{"key":"2025110308151212000_8.11.e202503469.50","doi-asserted-by":"publisher","DOI":"10.1126\/science.282.5390.941"},{"key":"2025110308151212000_8.11.e202503469.51","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.06.139"},{"key":"2025110308151212000_8.11.e202503469.52","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0101-18.2018"},{"key":"2025110308151212000_8.11.e202503469.53","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20210040"},{"key":"2025110308151212000_8.11.e202503469.54","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2023.0117"},{"key":"2025110308151212000_8.11.e202503469.55","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3023"},{"key":"2025110308151212000_8.11.e202503469.56","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1006683107"},{"key":"2025110308151212000_8.11.e202503469.57","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2012.2353"},{"key":"2025110308151212000_8.11.e202503469.58","doi-asserted-by":"publisher","DOI":"10.1007\/s10719-017-9765-8"},{"key":"2025110308151212000_8.11.e202503469.59","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-40901-2"},{"key":"2025110308151212000_8.11.e202503469.60","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.05.050"},{"key":"2025110308151212000_8.11.e202503469.61","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(85)90119-0"},{"key":"2025110308151212000_8.11.e202503469.62","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-17-07526.2002"},{"key":"2025110308151212000_8.11.e202503469.63","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2021.12.008"},{"key":"2025110308151212000_8.11.e202503469.64","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-024-01684-6"},{"key":"2025110308151212000_8.11.e202503469.65","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cws166"},{"key":"2025110308151212000_8.11.e202503469.66","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/60.7.676"},{"key":"2025110308151212000_8.11.e202503469.67","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1999.7118"},{"key":"2025110308151212000_8.11.e202503469.68","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-019-0424-1"},{"key":"2025110308151212000_8.11.e202503469.69","doi-asserted-by":"publisher","DOI":"10.1016\/0959-4388(94)90139-2"},{"key":"2025110308151212000_8.11.e202503469.70","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2015.08.002"},{"key":"2025110308151212000_8.11.e202503469.71","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-019-0274-x"},{"key":"2025110308151212000_8.11.e202503469.72","doi-asserted-by":"publisher","DOI":"10.1038\/nature11499"},{"key":"2025110308151212000_8.11.e202503469.73","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.02.012"},{"key":"2025110308151212000_8.11.e202503469.74","doi-asserted-by":"publisher","DOI":"10.1126\/science.1178310"},{"key":"2025110308151212000_8.11.e202503469.75","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2014.03.016"},{"key":"2025110308151212000_8.11.e202503469.76","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a020602"},{"key":"2025110308151212000_8.11.e202503469.77","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0068-4"},{"key":"2025110308151212000_8.11.e202503469.78","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-020-00777-2"},{"key":"2025110308151212000_8.11.e202503469.79","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1998.6835"},{"key":"2025110308151212000_8.11.e202503469.80","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2015.08.005"},{"key":"2025110308151212000_8.11.e202503469.81","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2022.813841"},{"key":"2025110308151212000_8.11.e202503469.82","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29040764"},{"key":"2025110308151212000_8.11.e202503469.83","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwi050"},{"key":"2025110308151212000_8.11.e202503469.84","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-021-03477-w"},{"key":"2025110308151212000_8.11.e202503469.85","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.05.006"},{"key":"2025110308151212000_8.11.e202503469.86","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2006.10.007"},{"key":"2025110308151212000_8.11.e202503469.87","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2000.3141"},{"key":"2025110308151212000_8.11.e202503469.88","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M106587200"},{"key":"2025110308151212000_8.11.e202503469.89","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M104719200"},{"key":"2025110308151212000_8.11.e202503469.90","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M404456200"},{"key":"2025110308151212000_8.11.e202503469.91","doi-asserted-by":"publisher","DOI":"10.1038\/ni1258"},{"key":"2025110308151212000_8.11.e202503469.92","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl087"},{"key":"2025110308151212000_8.11.e202503469.93","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd8811"},{"key":"2025110308151212000_8.11.e202503469.94","doi-asserted-by":"publisher","DOI":"10.1002\/ar.22549"},{"key":"2025110308151212000_8.11.e202503469.95","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-020-0585-y"},{"key":"2025110308151212000_8.11.e202503469.96","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwi092"},{"key":"2025110308151212000_8.11.e202503469.97","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwac025"},{"key":"2025110308151212000_8.11.e202503469.98","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3943-11.2011"},{"key":"2025110308151212000_8.11.e202503469.99","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1615036114"},{"key":"2025110308151212000_8.11.e202503469.100","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-022-00562-y"}],"container-title":["Life Science Alliance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.26508\/lsa.202503469","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:15:18Z","timestamp":1762186518000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.life-science-alliance.org\/lookup\/doi\/10.26508\/lsa.202503469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,28]]},"references-count":100,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2025,8,28]]},"published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.26508\/lsa.202503469"],"URL":"https:\/\/doi.org\/10.26508\/lsa.202503469","relation":{},"ISSN":["2575-1077"],"issn-type":[{"value":"2575-1077","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,28]]}}}