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In parallel, we find that the\n                    <jats:italic>Flamenco<\/jats:italic>\n                    (\n                    <jats:italic>Flam<\/jats:italic>\n                    ) uni-strand piRNA cluster, the principal source of somatic piRNAs, undergoes structural remodeling in ovarian somatic cells, replacing antisense transposon fragments with forward-oriented copies. This remodeling reshapes piRNA populations and erodes silencing of specific elements, including\n                    <jats:italic>Springer<\/jats:italic>\n                    . This relaxation of somatic repression may create conditions permissive for continued transposon activity, with possible broader implications for genome change. Our findings suggest that\n                    <jats:italic>Flam<\/jats:italic>\n                    plasticity can couple transposon activity to genome rewiring, with potential evolutionary consequences.\n                  <\/jats:p>","DOI":"10.26508\/lsa.202603650","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T06:21:47Z","timestamp":1775283707000},"page":"e202603650","update-policy":"https:\/\/doi.org\/10.26508\/lsa.crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Flamenco<\/i>\n                    plasticity tunes somatic piRNAs and rewires isoforms, with implications for heritable transposon spread"],"prefix":"10.26508","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5501-3727","authenticated-orcid":true,"given":"Mai","family":"Moritoh","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/057zh3y96","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Biological Sciences, 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