{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T07:03:27Z","timestamp":1785135807218,"version":"3.55.0"},"reference-count":14,"publisher":"Tsinghua University Press","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the prevalence, severity, and audiometric characteristics of age-related hearing loss (ARHL) in older Chinese adults attending a tertiary otolaryngology clinic, with emphasis on age- and sex-specific patterns based on the updated World Health Organization (WHO 2020) criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this cross-sectional study, 1,000 adults aged \u226560 years underwent otologic examination, tympanometry, and pure-tone audiometry at a tertiary medical center between March 2022 and January 2023. Individuals with abnormal tympanograms or evidence of middle ear disease were excluded. Pure-tone averages (0.5, 1, 2, and 4 kHz) from the better ear were used to define and grade ARHL. Age- and sex-related differences in hearing thresholds were assessed using chi-square tests, t-tests, and two-way ANOVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Within this tertiary-care outpatient cohort, the prevalence of hearing loss according to WHO 2020 criteria was 84.1%, rising from 78.3% in the 60s to 100% in those aged over 90 years. Hearing thresholds showed a consistent high-frequency\u2013sloping configuration, with high-frequency (8,000 Hz) thresholds declining at nearly double the rate of low-to-mid frequencies (11.7 dB vs. 4.5\u20136.3 dB per decade). The steepest decadal deterioration occurred between the 70s and 80s, characterized by a transition from high-frequency sensory loss to generalized cochlear decline. A sex-dependent \"crossover\" was observed: females exhibited superior hearing in their 60s and 70s but experienced more rapid deterioration in late life, resulting in comparable or poorer thresholds than males by their 80s and 90s.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this tertiary-care outpatient cohort of older Chinese adults, ARHL demonstrated distinct age- and sex-specific trajectories,including disproportionate high-frequency vulnerability and a late-life sex crossover effect. Adoption of WHO 2020 criteria substantially increased hearing-loss identification, particularly among adults in their 60s and 70s.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.26599\/joto.2026.9540072","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T06:41:34Z","timestamp":1785134494000},"page":"191-196","source":"Crossref","is-referenced-by-count":0,"title":["High-Frequency Vulnerability and Sex Differences in Age-Related Hearing Loss: A Cross-Sectional Audiometric Analysis of Older Chinese Otolaryngology Outpatients"],"prefix":"10.26599","volume":"21","author":[{"given":"Hongyi","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiatao","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingchao","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11138","reference":[{"issue":"8","key":"ref1","doi-asserted-by":"publisher","first-page":"a033217","DOI":"10.1101\/cshperspect.a033217","article-title":"Age-related hearing loss","volume":"9","author":"M.R. 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