{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T18:44:22Z","timestamp":1746816262179},"reference-count":27,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,12,20]]},"abstract":"<p><italic>This article synthesizes the important lessons learned from polio eradication in the Region of the Americas, including initial and more recent challenges and best practices, as well as particular factors surrounding attainment of this ambitious goal. Using documents, interviews, and country surveys, the authors describe and analyze the strategies and lessons learned during the 40 years of the Expanded Program on Immunization (1977 \u2013 2017). Some major milestones and chxallenges specifically covered are: the Vaccine-derived Poliovirus (VDPV) outbreak in the Dominican Republic; the regional \u201cmop-up operation;\u201d poliovirus containment in essential facilities; the unprecedented introduction of inactivated polio vaccine (IPV); the synchronized switch from trivalent to bivalent OPV; and the countries\u2019 unfailing commitment to the cause<\/italic>.<\/p>","DOI":"10.26633\/rpsp.2017.154","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T12:55:06Z","timestamp":1519649706000},"page":"1","source":"Crossref","is-referenced-by-count":3,"title":["The path towards polio eradication over 40 years of the Expanded Program on Immunization in the Americas"],"prefix":"10.26633","volume":"41","author":[{"given":"Cristina","family":"Pedreira","sequence":"additional","affiliation":[{"name":"Immunization Unit, Pan American Health Organization, Regional Office of the World Health Organization, Washington, DC, United States of America. Send correspondence to Cristina Pedreira, mcp_dor@hotmail.com"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Thrush","sequence":"additional","affiliation":[{"name":"Immunization Unit, Pan American Health Organization, Regional Office of the World Health Organization, Washington, DC, United States of America."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Rey-Benito","sequence":"additional","affiliation":[{"name":"Immunization Unit, Pan American Health Organization, Regional Office of the World Health Organization, Washington, DC, United States of America."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Elena","family":"Ch\u00e9vez","sequence":"additional","affiliation":[{"name":"Immunization Unit, Pan American Health Organization, Regional Office of the World Health Organization, Washington, DC, United States of America."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Jauregui","sequence":"additional","affiliation":[{"name":"Immunization Unit, Pan American Health Organization, Regional Office of the World Health Organization, Washington, DC, United States of America."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11167","reference":[{"key":"ref1","unstructured":"1. World Health Organization. Expanded Program on Immunization. Proceedings of the 27th World Health Assembly. Geneva: WHO; 1974. Available from: http:\/\/apps.who.int\/iris\/handle\/10665\/92778 Accessed 17 April 2017."},{"key":"ref2","unstructured":"2. Pan American Health Organization. The Expanded Program on Immunization for the Americas. Proceedings of the 25th PAHO Directing Council. Washington DC: PAHO; 1977. Available from: http:\/\/iris.paho.org\/xmlui\/handle\/123456789\/2381 Accessed 15 March 2017."},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"3. Hampton L. Albert Sabin and the coalition to eliminate polio from the Americas. Am J Public Health. 2009;99 (1):34- 44. Available from: http:\/\/ajph.aphapublications.org\/doi\/abs\/10.2105\/AJPH.2007.117952 Accessed 1 March 2017.","DOI":"10.2105\/AJPH.2007.117952"},{"key":"ref4","unstructured":"4. Pan American Health Organization. Expanded Program on Immunization in the Americas Progress Report. Washington DC: PAHO; 1985. Available from: http:\/\/iris.paho.org\/xmlui\/handle\/123456789\/30544 Accessed 1 March 2017."},{"key":"ref5","unstructured":"5. Lago PM. Eradication of poliomyelitis in Cuba: a historical perspective. Bull World Health Organ. 1999;1;77 (8):681-7. Available from: www.who.int\/bulletin\/archives\/77(8)681.pdf Accessed 21 April 2017."},{"key":"ref6","unstructured":"6. Pan American Health Organization. Final Report of the Eleventh Technical Advisory Group (TAG) Meeting on Vaccine-Preventable Diseases of the Pan American Health Organization and the Third Meeting of the International Commission for the Certification of Poliomyelitis Eradication (ICCPE). Washington DC: PAHO; 1994. Available from: http:\/\/www2.paho.org\/hq\/index.php?option=com_docman&task=doc_download&gid=36701&Itemid=270&lang=en Accessed 1 March 2017."},{"key":"ref7","unstructured":"7. Pan American Health Organization. Expanded Program on Immunization in the Americas Progress report. Proceedings of the 95th Executive Committee. Washington DC: PAHO; 1985. Available from: http:\/\/iris.paho.org\/xmlui\/handle\/123456789\/25619 Accessed 1 March 2017."},{"key":"ref8","unstructured":"8. Hinman AR. The case for global eradication of poliomyelitis. Bull World Health Organ. 1987;65 (6):835-40. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2491079\/ Accessed 3 March 2017."},{"key":"ref9","unstructured":"9. Pan American Health Organization. Expanded Program on Immunization in the Americas. Proceedings of the 31st Directing Council. Washington DC: PAHO; 1985. Available from: http:\/\/iris.paho.org\/xmlui\/handle\/123456789\/2296 Accessed 1 March 2017."},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"10. Kaslow RA, Stanberry LR, Le Duc JW, eds. Viral infections of humans: epidemiology and control. New York: Springer; 2014.","DOI":"10.1007\/978-1-4899-7448-8"},{"key":"ref11","unstructured":"11. Pan American Health Organization. Expanded Program on Immunization in the Americas. Proceedings of the 31st PAHO Directing Council. Washington DC: PAHO; 1977. Available from: http:\/\/iris.paho.org\/xmlui\/handle\/123456789\/2381 Accessed 15 March 2017."},{"key":"ref12","unstructured":"12. Pan American Health Organization. EPI Global Advisory Group Recommendations. EPI Newsl. 1985;6 (4):4-5. Available from: www.paho.org\/english\/ad\/fch\/im\/sne0704.pdf Accessed 1 March 2017."},{"key":"ref13","unstructured":"13. Pan American Health Organization. Plan of action for the eradication of the indigenous transmission of wild poliovirus. Washington DC: PAHO; 1985. Available from: http:\/\/iris.paho.org\/xmlui\/bitstream\/handle\/123456789\/6725\/25973.pdf?sequence=1&isAllowed=y Accessed 1 March 2017."},{"key":"ref14","unstructured":"14. Pan American Health Organization. Polio surveillance in the Americas: first 8 weeks of 1986. EPI Newsl. 1986;8 (1):1-8. Available from: www.paho.org\/english\/ad\/fch\/im\/sne0801.pdf Accessed 1 March 2017."},{"key":"ref15","unstructured":"15. Daniel TM, Robbins FC, eds. A history of poliomyelitis. Rochester, New York: University of Rochester Press; 1997:5\u201322."},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"16. Campos AL1, Nascimento DR, Maranh\u00e3o E. The history of polio in Brazil and its control through immunization. Hist Cienc Saude Manguinhos. 2003;10(Suppl 2):573-600.","DOI":"10.1590\/S0104-59702003000500007"},{"key":"ref17","unstructured":"17. Taylor Commission. The impact of the Expanded Program on Immunization and the polio eradication initiative on health systems in the Americas. Washington DC: Pan American Health Organization; 1995."},{"key":"ref18","unstructured":"18. Pan American Health Organization. The Americas conquer polio! EPI Newsl. 1994;16 (4): 1-6. Available from: www.paho.org\/english\/ad\/fch\/im\/sne1604.pdf Accessed 1 March 2017."},{"key":"ref19","unstructured":"19. Landaverde M, Venczel L, de Quadros C. Poliomyelitis outbreak caused by vaccine-derived virus in Haiti and the Dominican Republic. Pan Am J Public Health. 2001;9 (4): 272-4. Available from: www.scielosp.org\/scielo.php?script=sci_arttext&pid=S1020-49892001000400017 Accessed 1 March 2017."},{"key":"ref20","unstructured":"20. Kew O, Morris-Glasgow V, Landaverde M, Burns C, Shaw J, Garib Z, et al. Outbreak of poliomyelitis in Hispaniola associated with circulating type 1 vaccine-derived poliovirus. Science. 2002;296 (5566):356-9. Available from: http:\/\/science.sciencemag.org\/content\/296\/5566\/356.short Accessed 1 March 2017."},{"key":"ref21","unstructured":"21. World Health Organization. Global eradication of poliomyelitis by the year 2000. Proceedings of the 41st World Health Assembly. Geneva: WHO; 1988. Available from: http:\/\/apps.who.int\/iris\/handle\/10665\/62212 Accessed 17 April 2017."},{"key":"ref22","unstructured":"22. Donaldson L, El Sayed N, Koplan J, Nduati R, Toole M, de Quadros C, et al. Report of the Independent Monitoring Board of the Global Polio Eradication Initiative. Geneva: WHO; 2011. Available from: http:\/\/www.who.int\/immunization\/sage\/3_GPEI_IMB_report_Oct2011_nov11.pdf Accessed 17 April 2017."},{"key":"ref23","unstructured":"23. World Health Organization. Poliomyelitis: intensification of the global eradication initiative. Proceedings of the 65th World Health Assembly. Geneva: WHO; 2012. Available from: http:\/\/apps.who.int\/gb\/ebwha\/pdf_files\/wha65\/a65_r5-en.pdf Accessed 17 April 2017."},{"key":"ref24","unstructured":"24. Global Polio Eradication Initiative. Polio eradication & endgame Strategic Plan 2013\u20132018. Geneva: WHO; 2013. Available from: http:\/\/polioeradication.org\/wp-content\/uploads\/2016\/07\/PEESP_EN_A4.pdf Accessed 17 April 2017."},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"25. Pedreira C, Thrush E, Jauregui B. Systematization of the introduction of IPV and switch from tOPV to bOPV in the Americas. J Infec Dis. 2017;216(suppl_1):S76-85.","DOI":"10.1093\/infdis\/jiw557"},{"key":"ref26","unstructured":"26. World Health Organization. Global Action Plan to minimize poliovirus facility-associated risk after type-specific eradication of wild polioviruses and sequential cessation of oral polio vaccine use. Geneva: WHO; 2014. Available from: http:\/\/polioeradication.org\/wp-content\/uploads\/2016\/12\/GAPIII_2014.pdf Accessed 17 April 2017."},{"key":"ref27","unstructured":"27. Pan American Health Organization. Regional Plan for Containment of Poliovirus in the Americas. Washington DC: PAHO; 2015. 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