{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:46:37Z","timestamp":1790567197891,"version":"4.1.0"},"reference-count":13,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7,1]]},"abstract":"<p><italic>El 6 de diciembre de 2013, la Organizaci\u00f3n Panamericana de la Salud (OPS) y la Organizaci\u00f3n Mundial de la Salud (OMS) notificaron la confirmaci\u00f3n de los dos primeros casos de transmisi\u00f3n aut\u00f3ctona en la Regi\u00f3n de las Am\u00e9ricas de fiebre chikungunya (CHIK) en la isla de Saint Martin (Antillas Neerlandesas). Para el per\u00edodo 2013-2014, el total de casos confirmados fue de 25 627 distribuidos en 43 pa\u00edses, donde M\u00e9xico report\u00f3 155 casos en cinco estados. La informaci\u00f3n de los casos de CHIK en M\u00e9xico se obtuvo de la base de datos de la Direcci\u00f3n General de Epidemiolog\u00eda, dependiente de la Secretar\u00eda de Salud de M\u00e9xico. La distribuci\u00f3n por sexo de los casos aut\u00f3ctonos confirmados de CHIK para el a\u00f1o 2015 indica 64% para el sexo femenino (5 583) y 36% para el sexo masculino (3 085). Los s\u00edntomas m\u00e1s frecuentes fueron: fiebre en 98% de los casos (8 564), seguido por cefalea con 91,6% (7 941), mialgias en 89,9% (7 792), artralgias leves en 73,5% (6 367), poliartralgias graves en 72,6% (6 295) y exantema en 58% (5 032). La presentaci\u00f3n cl\u00ednica de los casos aut\u00f3ctonos de CHIK en M\u00e9xico ha mostrado algunas caracter\u00edsticas cl\u00ednicas diferentes de las que se han observado en los brotes de los pa\u00edses africanos, asi\u00e1ticos y otras regiones de Am\u00e9rica, como por ejemplo un mayor porcentaje de casos con cefalea y mialgias y un menor porcentaje de casos con artralgias.<\/italic><\/p>","DOI":"10.26633\/rpsp.2017.58","type":"journal-article","created":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T05:03:52Z","timestamp":1562562232000},"page":"1","source":"Crossref","is-referenced-by-count":1,"title":["Caracterizaci\u00f3n cl\u00ednica y epidemiol\u00f3gica de fiebre chikungunya en M\u00e9xico"],"prefix":"10.26633","volume":"41","author":[{"given":"Jos\u00e9 Alberto","family":"D\u00edaz-Qui\u00f1onez","sequence":"first","affiliation":[{"name":"Instituto de Diagn\u00f3stico y Referencia Epidemiol\u00f3gicos \u201cDr. Manuel Mart\u00ednez B\u00e1ez\u201d, M\u00e9xico D.F., M\u00e9xico."},{"name":"alberto.diaz@salud.gob.mx"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Garay-Mor\u00e1n","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n General de Epidemiolog\u00eda, M\u00e9xico D.F., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Francisco","family":"Rom\u00e1n-Pedroza","sequence":"additional","affiliation":[{"name":"Instituto de Diagn\u00f3stico y Referencia Epidemiol\u00f3gicos \u201cDr. Manuel Mart\u00ednez B\u00e1ez\u201d, M\u00e9xico D.F., M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma","family":"L\u00f3pez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Instituto de Diagn\u00f3stico y Referencia Epidemiol\u00f3gicos \u201cDr. Manuel Mart\u00ednez B\u00e1ez\u201d, M\u00e9xico D.F., M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Cruz","family":"Rodr\u00edguez-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n General de Epidemiolog\u00eda, M\u00e9xico D.F., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuitl\u00e1huac","family":"Ruiz-Matus","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n General de Epidemiolog\u00eda, M\u00e9xico D.F., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Kuri-Morales","sequence":"additional","affiliation":[{"name":"Subsecretar\u00eda de Prevenci\u00f3n y Promoci\u00f3n de la Salud, M\u00e9xico D.F., M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11167","reference":[{"key":"ref1","unstructured":"1. 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