{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T17:24:34Z","timestamp":1772731474779,"version":"3.50.1"},"reference-count":25,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,23]]},"abstract":"<p><bold>Objetivo.<\/bold> Reportar las especies identificadas en candidemias aisladas en hospitales del pa\u00eds, su distribuci\u00f3n seg\u00fan los grupos etarios y determinar la sensibilidad a fluconazol, voriconazol y anfotericina B.<\/p>\n<p><bold>M\u00e9todos.<\/bold> Estudio retrospectivo de candidemias reportados por siete hospitales al Laboratorio Central de Salud P\u00fablica en el per\u00edodo 2010 - 2018. La identificaci\u00f3n y el antifungigrama fueron realizados en el sistema automatizado Vitek\u00ae2.<\/p>\n<p><bold>Resultados.<\/bold> Se informaron 520 casos de candidemias. Las especies prevalentes fueron Candida albicans (34,4%), C. parapsilosis (30,4%), C. tropicalis (25,4%), C. glabrata (4,8%), C. krusei (2,1%). Otras menos frecuentes fueron: C. lusitaniae (1,2%), C. guilliermondii (1%), C. famata (0,3%), C. rugosa (0,2%) y C. kefyr (0,2%). Las candidemias en ancianos (48,5%) y adultos (29,9%) fueron las m\u00e1s prevalentes. C. parapsilosis fue m\u00e1s frecuente en reci\u00e9n nacidos y lactantes y C. tropicalis en pacientes pedi\u00e1tricos. El 2,8 % y 0,6% de C. albicans y el 4,4% y 2,5% de C. parapsilosis fueron resistentes a fluconazol y voriconazol, respectivamente. El 8% de C. glabrata fue resistente a fluconazol y dos aislamientos presentaron una concentraci\u00f3n inhibitoria m\u00ednima para voriconazol mayor que 0,25 mg\/L.<\/p>\n<p><bold>Conclusiones.<\/bold> Este es el primer reporte de candidemias en hospitales de Paraguay que, junto a otros estudios, permitir\u00e1 un mejor conocimiento de esta infecci\u00f3n en el pa\u00eds.<\/p>","DOI":"10.26633\/rpsp.2020.34","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T21:56:23Z","timestamp":1600379783000},"page":"1","source":"Crossref","is-referenced-by-count":6,"title":["Identificaci\u00f3n y perfil de sensibilidad de Candida spp. aisladas de hemocultivos en hospitales de Paraguay"],"prefix":"10.26633","volume":"44","author":[{"given":"Gustavo","family":"Aguilar","sequence":"first","affiliation":[{"name":"gaguifer@hotmail.com"},{"name":"Instituto de Previsi\u00f3n Social, Hospital Central, Asunci\u00f3n, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Araujo","sequence":"additional","affiliation":[{"name":"Laboratorio Central de Salud P\u00fablica, Ministerio de Salud, Asunci\u00f3n, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciela","family":"Lird","sequence":"additional","affiliation":[{"name":"Hospital de Cl\u00ednicas, San Lorenzo, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Insaurralde","sequence":"additional","affiliation":[{"name":"Hospital Nacional de Itagu\u00e1, Itagu\u00e1, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An\u00edbal","family":"Kawabata","sequence":"additional","affiliation":[{"name":"Hospital del Trauma \u201cProf. Dr. Manuel Giagni\u201d, Asunci\u00f3n, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edelira","family":"Ayala","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Tropical, Asunci\u00f3n, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Irala","sequence":"additional","affiliation":[{"name":"Hospital Militar, Asunci\u00f3n, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roc\u00edo","family":"Arg\u00fcello","sequence":"additional","affiliation":[{"name":"Hospital Pedi\u00e1trico \u201cNi\u00f1os de Acosta \u00d1u\u201d, San Lorenzo, Paraguay."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11167","reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Colombo AL, Nucci M, Park BJ, Nou\u00e9r SA, Arthington-Skaggs B, da Matta DA, et al. 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