{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:03:23Z","timestamp":1792677803715,"version":"4.5.0"},"reference-count":39,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,21]]},"abstract":"<sec>\n<title>Objective.<\/title>\n<p>To describe the prevalence of leptospirosis in the Americas.<\/p>\n<\/sec>\n<sec>\n<title>Methods.<\/title>\n<p>A systematic review and meta-analysis, in the period 1930 to 2017, performed on a search of six platforms: PubMed, Web of Science, Scopus, Lilacs, Embase, and Cochrane.<\/p>\n<\/sec>\n<sec>\n<title>Results.<\/title>\n<p>The search found 77 publications of which 53 (68%) were from the period 2000\u20132017. Of the 77, 62 studies were included in the analysis, from North America (11, 17%), Central America (9, 14%), and South America (42, 67%), and 22 studies were from urban areas. Leptospirosis prevalence in the 62 studies analyzed corresponded to 28% (95% CI [23, 32]). Countries with higher prevalence were United States of America (41%), Colombia (29%), and Brazil (21%). The most frequent serovars found were Icterohaemorrhagiae (43 of 77 publications, 55%), Canicola (35, 45%), Pomona (28, 36%), and Grippotyphosa (26, 33%).<\/p>\n<\/sec>\n<sec>\n<title>Conclusions.<\/title>\n<p>There is variability of <italic>Leptospira<\/italic> species and serovars with heterogenous distribution throughout the Americas, with high prevalence in some countries, highlighting the need for action to control the disease.<\/p>\n<\/sec>","DOI":"10.26633\/rpsp.2023.126","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T14:23:20Z","timestamp":1692627800000},"page":"1","source":"Crossref","is-referenced-by-count":25,"title":["Prevalence of human leptospirosis in the Americas: a systematic review and meta-analysis"],"prefix":"10.26633","volume":"47","author":[{"given":"Ericka Souza","family":"Browne","sequence":"first","affiliation":[{"name":"Universidade Federal da Bahia, Collective Health Institute, Salvador, Bahia, Brazil"},{"name":"ericka_browne@hotmail.com"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos","family":"Pereira","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia, Collective Health Institute, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Barreto","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia, Collective Health Institute, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caio Graco","family":"Zeppelini","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia, Collective Health Institute, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daiana de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Oswaldo Cruz Foundation, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Costa","sequence":"additional","affiliation":[{"name":"Universidade Federal da Bahia, Collective Health Institute, Salvador, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11167","reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Brito T de. 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