{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T16:20:05Z","timestamp":1789402805714,"version":"build-2803163510"},"reference-count":50,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,21]]},"abstract":"<sec>\n                    <title>Objectives.<\/title>\n                    <p>To assess the accumulated knowledge of the effects of public health emergencies of international concern on disease control and local health systems, and contribute to a better understanding of their effects on health programs and systems.<\/p>\n                  <\/sec>\n                  <sec>\n                    <title>Methods.<\/title>\n                    <p>This was a systematic review of published and gray literature (in English, Portuguese, or Spanish). Electronic databases (BVS\/LILACS, PubMed, and SciELO) and Google Scholar were searched. Search terms were: COVID-19 OR H1N1 OR Ebola OR Zika OR poliomyelitis AND (outbreaks OR epidemics) AND (public health systems OR public health surveillance).<\/p>\n                  <\/sec>\n                  <sec>\n                    <title>Results.<\/title>\n                    <p>A total of 3 508 studies were retrieved, of which 31 met the inclusion criteria. The studies addressed the effects of the emergencies on: communicable diseases notification systems; malaria, HIV\/AIDS, tuberculosis, poliomyelitis, and malaria surveillance, control, and treatment; microcephaly; dengue; and vaccinations. The populations affected by the emergencies experienced reduced health services, which included fewer health visits, failures in the diagnostic chain, decrease in vaccination, and increased incidence or underreporting of notifiable diseases.<\/p>\n                  <\/sec>\n                  <sec>\n                    <title>Conclusions.<\/title>\n                    <p>Socioeconomic inequity is a determinant of the effects of public health emergencies of international concern within affected populations. The diversion of resources and attention from health authorities disproportionately affects vulnerable populations and can lead, over time, to a weakening of health systems. The analysis of the effects of public health emergencies is important for the development of new protocols that can better respond to future crises.<\/p>\n                  <\/sec>","DOI":"10.26633\/rpsp.2023.74","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T09:13:02Z","timestamp":1682068382000},"page":"1","source":"Crossref","is-referenced-by-count":19,"title":["Effects of public health emergencies of international concern on disease control: a systematic review"],"prefix":"10.26633","volume":"47","author":[{"given":"Giovanna Rotondo","family":"de Ara\u00fajo","sequence":"first","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro A.S.V.","family":"de Castro","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela R.","family":"\u00c1vila","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Maria T.","family":"Bezerra","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brasil."},{"name":"davidsoeiro@gmail.com"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11167","reference":[{"key":"ref1","unstructured":"World Health Organization. International Health Regulations [Internet]. Geneva: WHO 2005 [cited 2022 Apr 27] Available at: https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/246107\/9789241580496-eng.pdf"},{"key":"ref2","unstructured":"World Health Organization. IHR emergency committees [Internet]. Geneva: WHO [cited 2022 Apr 27]. Available at: https:\/\/www.who.int\/teams\/ihr\/ihr-emergency-committees"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Hotez PJ. Neglected tropical diseases in the Ebola-affected countries of West Africa. PLoS Negl Trop Dis. 2015;9:e0003671","DOI":"10.1371\/journal.pntd.0003671"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Parpia AS, Ndeffo-Mbah ML, Wenzel NS, Galvani AP. Effects of response to 2014\u20132015 Ebola outbreak on deaths from Malaria, HIV\/AIDS, and tuberculosis, West Africa. Emerg Infect Dis. 2016;22:433\u201341.","DOI":"10.3201\/eid2203.150977"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Effects of the West Africa Ebola virus disease on health-care utilization \u2013 A systematic review. Front Public Health. 2016;4:222.","DOI":"10.3389\/fpubh.2016.00222"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"J\u00fanior JPB, Santos DB. COVID-19 como sindemia: modelo te\u00f3rico e fundamentos para a abordagem abrangente em sa\u00fade. Cad Sa\u00fade P\u00fablica. 2021;37:e00119021.","DOI":"10.1590\/0102-311x00119021"},{"key":"ref7","unstructured":"PROSPERO. International Prospective Register of Systematic Reviews [Internet] [cited 2022 Apr 27]. Available at: https:\/\/www.crd.york.ac.uk\/prospero\/display_record.php?RecordID=257860"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.","DOI":"10.1136\/bmj.n71"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetc R, et al. Chapter 7. Systematic reviews of etiology and risk. In: Aromataris E, Munn Z, Editors. JBI manual for evidence synthesis. Adelaide: JBI; 2020 [cited 2022 Apr 27]. Available at: https:\/\/synthesismanual.jbi.global","DOI":"10.46658\/JBIRM-17-06"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Mecenas P, Bastos RTDRM, Vallinoto ACR, Normando D. Effects of temperature and humidity on the spread of COVID-19: a systematic review. PLoS One. 2020;15:e0238339","DOI":"10.1371\/journal.pone.0238339"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Elston JW, Moosa AJ, Moses F, Walker G,Dotta N, Waldman RJ, et al. Impact of the Ebola outbreak on health systems and population health in Sierra Leone. J Public Health (Oxf). 2016;38:673\u20138.","DOI":"10.1093\/pubmed\/fdv158"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Kolie D, Camara BS, Delamou A, B\u00e9avogui AH, Hermans V, Edwards JK, et al. The Ebola-effect in Guinea 2014\u201315: tangled trends of malaria care in children under-five. PLoS One. 2018;13:e0192798.","DOI":"10.1371\/journal.pone.0192798"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"McLean KE, Abramowitz SA, Ball JD, Monger J, Tehoungue K, McKune SL, et al. Community-based reports of morbidity, mortality, and health-seeking behaviours in four Monrovia communities during the West African Ebola epidemic. Glob Public Health. 2018;13:528\u201344.","DOI":"10.1080\/17441692.2016.1208262"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"McQuilkin PA, Udhayashankar K, Niescierenko M, Maranda L. Health-care access during the Ebola virus epidemic in Liberia. Am J Trop Med Hyg. 2017;97:931\u20136.","DOI":"10.4269\/ajtmh.16-0702"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Moses FL, Tamang D, Denisiuk O, Dumbuya U, Hann K, Zachariah R. Management of malaria in children with fever in rural Sierra Leone in relation to the 2014\u20132015 Ebola outbreak. Public Health Action. 2017;7:S22\u20136.","DOI":"10.5588\/pha.16.0085"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Plucinski MM, Guilavogui T, Sidikiba S, Diakit\u00e9 N, Diakit\u00e9 S, Dioubat\u00e9 M, et al. Effect of the Ebola-virus-disease epidemic on malaria case management in Guinea, 2014: a cross-sectional survey of health facilities. Lancet Infect Dis. 2015;15:1017\u20131023.","DOI":"10.1016\/S1473-3099(15)00061-4"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Sesay T, Denisiuk O, Shringarpure KK, Wurie BS, George P, Sesay MI, et al. Paediatric care in relation to the 2014\u20132015 Ebola outbreak and general reporting of deaths in Sierra Leone. Public Health Action. 2017;7:S34\u20139.","DOI":"10.5588\/pha.16.0088"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Vygen S, Tiffany A, Rull M, Ventura A, Wolz A, Jambai A, et al. Changes in health-seeking behavior did not result in increased all-cause mortality during the Ebola outbreak in Western Area, Sierra Leone. Am J Trop Med Hyg. 2016;95:897\u2013901.","DOI":"10.4269\/ajtmh.16-0295"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Camara BS, Delamou AM, Diro E, El Ayadi A, B\u00e9avogui AH, Sidib\u00e9 S, et al. Influence of the 2014\u20132015 Ebola outbreak on the vaccination of children in a rural district of Guinea. Public Health Action. 2017;7:161\u20137.","DOI":"10.5588\/pha.16.0120"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Delamou A, Ayadi AME, Sidibe S, Delvaux T, Camara BS, Sandouno SD, et al. Effect of Ebola virus disease on maternal and child health services in Guinea: a retrospective observational cohort study. Lancet Glob Health. 2017;5:e448\u201357.","DOI":"10.1016\/S2214-109X(17)30078-5"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Fernandez-Garcia MD, Majumdar M, Kebe O, Fall AD, Kone M, Kande M, et al. Emergence of vaccine-derived polioviruses during Ebola virus disease outbreak, Guinea, 2014-2015. Emerg Infect Dis. 2018;24:65\u201374.","DOI":"10.3201\/eid2401.171174"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Suk JE, Paez Jimenez A, Kourouma M, Derrough T, Bald\u00e9 M, Honomou P, et al. Post-Ebola measles outbreak in Lola, Guinea, January\u2013June 2015. Emerg Infect Dis. 2016;22:1106\u20138.","DOI":"10.3201\/eid2206.151652"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Sun X, Samba TT, Yao J, Yin W, Xiao L, Liu F, et al. Impact of the Ebola outbreak on routine immunization in western area, Sierra Leone \u2013 a field survey from an Ebola epidemic area. BMC Public Health. 2017;17:363.","DOI":"10.1186\/s12889-017-4242-7"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Gamanga AH, Owiti P, Bhat P, Harries AD, Kargbo-Labour I, Koroma M. The Ebola outbreak: effects on HIV reporting, testing and care in Bonthe district, rural Sierra Leone. Public Health Action. 2017;7:S10\u20135.","DOI":"10.5588\/pha.16.0087"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Leno NN, Delamou A, Koita Y, Diallo TS, Kaba A, Delvaux T, et al. Ebola virus disease outbreak in Guinea: what effects on prevention of mother-to-child transmission of HIV services? Reprod Health. 2018;15:60.","DOI":"10.1186\/s12978-018-0502-y"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Nagel E, Blackowicz MJ, Sahr F, Jarrett OD. Impact of the Ebola epidemic on clinical outcomes of HIV-infected soldiers and their dependents in Sierra Leone. Int J STD AIDS. 2019;30:106\u201312.","DOI":"10.1177\/0956462418797843"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Magassouba AS, Diallo BD, Camara LM, Sow K, Camara S, Bah B, et al. Impact of the Ebola virus disease outbreak (2014\u20132016) on tuberculosis surveillance activities by Guinea\u2019s National Tuberculosis Control Program: a time series analysis. BMC Public Health. 2020;20:1200.","DOI":"10.1186\/s12889-020-09230-2"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Barcellos C, Xavier DR, Pav\u00e3o AL, Boccolini CS, Pina MF, Pedroso M, et al. Increased hospitalizations for neuropathies as indicators of Zika virus infection, according to health information system data, Brazil. Emerg Infect Dis. 2016;22:1894\u20139.","DOI":"10.3201\/eid2211.160901"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Mendivelso DFO, Garc\u00eda RA, Bedoya RM, R\u00e1ngel SG. Notificaci\u00f3n de defectos cong\u00e9nitos por brote del virus del Zika en Colombia, 2015\u20132017. Rev Panam Salud Publica. 2019;43:e38.","DOI":"10.26633\/RPSP.2019.38"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Hurtado-Villa P, Puerto AK, Victoria S, Gracia G, Guasmay\u00e1n L, Arce P, et al. Raised frequency of microcephaly related to Zika virus infection in two birth defects surveillance systems in Bogot\u00e1 and Cali, Colombia. Pediatr Infect Dis. J 2017;36:1017\u20139.","DOI":"10.1097\/INF.0000000000001670"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Mora-Salamanca AF, Porras-Ram\u00edrez A, Restrepo FPH. Burden of disease due to microcephaly associated with the Zika virus in Colombia. Cad Saude Publica. 2020;36:e00215319.","DOI":"10.1590\/0102-311x00215319"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Oliveira WK, de Fran\u00e7a GVA, Carmo EH, Duncan BB, de Souza Kuchenbecker R, Schmidt MI. Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis. Lancet. 2017;390:861\u201370.","DOI":"10.1016\/S0140-6736(17)31368-5"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Pimentel R, Khosla S, Rondon J, Pe\u00f1a F, Sullivan G, Perez M, et al. Birth defects and long-term neurodevelopmental abnormalities in infants born during the Zika virus epidemic in the Dominican Republic. Ann Glob Health. 2021;87:4.","DOI":"10.5334\/aogh.3095"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Vissoci JRN, Rocha TAH, Silva NCD, de Sousa Queiroz RC, Thomaz EBAF, Amaral PVM, et al. Zika virus infection and microcephaly: evidence regarding geospatial associations. PLoS Negl Trop Dis. 2018;12:e0006392.","DOI":"10.1371\/journal.pntd.0006392"},{"key":"ref35","doi-asserted-by":"crossref","unstructured":"Morgan J, Strode C, Salcedo-Sora JE. Climatic and socio-economic factors supporting the co-circulation of dengue, Zika and chikungunya in three different ecosystems in Colombia. PLoS Negl Trop Dis. 2021;15:e0009259.","DOI":"10.1371\/journal.pntd.0009259"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Mugabe VA, Borja LS, Cardoso CW, Weaver SC, Reis MG, Kitron U, et al. Changes in the dynamics of dengue incidence in South and Central America are possibly due to cross-population immunity after Zika virus epidemics. Trop Med Int Health. 2021;26:272\u201380.","DOI":"10.1111\/tmi.13526"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Oliveira JF, Rodrigues MS, Skalinski LM, Santos AES, Costa LC, Cardim LL, et al. Interdependence between confirmed and discarded cases of dengue, chikungunya and Zika viruses in Brazil: a multivariate time-series analysis. PLoS One. 2020;15:e0228347.","DOI":"10.1371\/journal.pone.0228347"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"Benschop KS, Albert J, Anton A, Andr\u00e9s C, Aranzamendi M, Armannsd\u00f3ttir B, et al. Re-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021. Euro Surveill. 2021;26:2100998.","DOI":"10.2807\/1560-7917.ES.2021.26.45.2100998"},{"key":"ref39","doi-asserted-by":"crossref","unstructured":"Zomahoun DJ, Burman AL, Snider CJ, Chauvin C, Gardner T, Lickness JS, et al. Impact of COVID-19 pandemic on global poliovirus surveillance. MMWR 2021;69:1648\u201352.","DOI":"10.15585\/mmwr.mm695152a4"},{"key":"ref40","doi-asserted-by":"crossref","unstructured":"Buonsenso D, Iodice F, Cinicola B, Raffaelli F, Sowa S, Ricciardi W. Management of malaria in children younger than 5 years old during coronavirus disease 2019 pandemic in Sierra Leone: a lesson learned? Front Pediatr. 2021;8:587638.","DOI":"10.3389\/fped.2020.587638"},{"key":"ref41","doi-asserted-by":"crossref","unstructured":"Cox A, Guglielmetti P, Coulombier D. Assessing the impact of the 2009 H1N1 influenza pandemic on reporting of other threats through the early warning and response system. Euro Surveill. 2009;14:19397.","DOI":"10.2807\/ese.14.45.19397-en"},{"key":"ref42","unstructured":"World Health Organization. Continuity of essential health services: facility assessment tool: a module from the suite of health service capacity assessments in the context of the COVID-19 pandemic: interim guidance 20 October 2020. Geneva: WHO; 2020 [cited 2022 Sep 29]. Available at: https:\/\/apps.who.int\/iris\/handle\/10665\/336254"},{"key":"ref43","unstructured":"Pan American Health Organization. Epidemiological update dengue in the context of COVID-19. Washington, D.C: PAHO; 2020 [cited 2022 Apr 27]. Available at: https:\/\/iris.paho.org\/bitstream\/handle\/10665.2\/53174\/EpiUpdate3December2020_eng.pdf?sequence=1&isAllowed=y"},{"key":"ref44","unstructured":"Pan American Health Organization. OPAS: 70% das pessoas com Chagas n\u00e3o sabem que est\u00e3o infectadas [Internet]. Washington, D.C: PAHO; 2020 [cited 2022 Apr 27]. Available at: https:\/\/www.paho.org\/pt\/noticias\/13-4-2021-opas-70-das-pessoas-com-chagas-nao-sabem-que-estao-infectadas"},{"key":"ref45","unstructured":"Pan American Health Organization. Measures to ensure the continuity of the response to malaria in the Americas during the COVID-19 pandemic, 24 April 2020. Washington, D.C: PAHO; 2020 [cited 2022 Apr 27]. Available at: https:\/\/iris.paho.org\/handle\/10665.2\/52080"},{"key":"ref46","unstructured":"Pan American Health Organization. Leishmanioses: informe epidemiol\u00f3gico das Am\u00e9ricas, No. 10. 2021. Washington, D.C: PAHO; 2021 [cited 2022 Apr 27]. Available at: https:\/\/iris.paho.org\/handle\/10665.2\/55386"},{"key":"ref47","unstructured":"Minist\u00e9rio da Sa\u00fade. Portaria No - 204, de 17 de fevereiro de 2016 [Internet]. Brasilia: Minist\u00e9rio da Sa\u00fade; 2016 [cited 2022 Apr 27]. Available at: https:\/\/bvsms.saude.gov.br\/bvs\/saudelegis\/gm\/2016\/prt0204_17_02_2016.html"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Suryana K. Coronavirus disease 2019, dengue hemorrhagic fever, and the clinical similarity. Asian J Pharm Clin Res. 2020;9:1\u20133.","DOI":"10.22159\/ajpcr.2020.v13i9.38454"},{"key":"ref49","unstructured":"Chris B, Singh S, Sudarshi D. Neglected tropical diseases, conflict, and the right to health. In: Institute of Medicine (US) Forum on Microbial Threats. The causes and impacts of neglected tropical and zoonotic diseases: opportunities for integrated intervention strategies. Washington, D.C.: National Academies Press (US); 2011 [cited 2022 Apr 27]. Available at: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK62508\/"},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"Atatah PE, Kisavi-Atatah CW. Globalization: revisiting neglected tropical diseases such as malaria and measles. Open J Soc Sci. 2015;3:45\u201356.","DOI":"10.4236\/jss.2015.311007"}],"container-title":["Revista Panamericana de Salud P\u00fablica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/iris.paho.org\/bitstream\/handle\/10665.2\/57396\/v47e742023.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T09:13:30Z","timestamp":1682068410000},"score":1,"resource":{"primary":{"URL":"https:\/\/iris.paho.org\/handle\/10665.2\/57396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,21]]},"references-count":50,"alternative-id":["RPSP.2023.74"],"URL":"https:\/\/doi.org\/10.26633\/rpsp.2023.74","relation":{},"ISSN":["1020-4989","1680-5348"],"issn-type":[{"value":"1020-4989","type":"print"},{"value":"1680-5348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,21]]}}}