{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T07:27:20Z","timestamp":1775114840043,"version":"3.50.1"},"reference-count":31,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,9]]},"abstract":"<title>RESUMO<\/title>\n<sec>\n<title>Objetivo.<\/title>\n<p>Descrever a ocorr\u00eancia dos casos de poliomielite associada ao v\u00edrus vacinal (PAVV) no Brasil no per\u00edodo de janeiro de 2013 a maio de 2023.<\/p>\n<\/sec>\n<sec>\n<title>M\u00e9todos.<\/title>\n<p>Foi realizado um estudo descritivo dos casos de PAVV notificados como eventos supostamente atribu\u00edveis \u00e0 vacina\u00e7\u00e3o ou imuniza\u00e7\u00e3o (ESAVI) pela vacina oral de poliov\u00edrus. Foram considerados como PAVV os casos de paralisia fl\u00e1cida aguda (PFA) com isolamento de v\u00edrus vacinal na amostra de fezes e persist\u00eancia do d\u00e9ficit ap\u00f3s 60 dias.<\/p>\n<\/sec>\n<sec>\n<title>Resultados.<\/title>\n<p>Foram identificados 200 casos suspeitos, sendo 2 confirmados como PAVV (&lt;1 caso\/10 milh\u00f5es de dose administradas) pelo isolamento do v\u00edrus vacinal. Os casos de PAVV apresentaram como condi\u00e7\u00e3o de risco o esquema vacinal incompleto, a desnutri\u00e7\u00e3o e\/ou a imunodefici\u00eancia.<\/p>\n<\/sec>\n<sec>\n<title>Conclus\u00f5es.<\/title>\n<p>A ocorr\u00eancia de PAVV foi rara e compat\u00edvel com os valores esperados. \u00c9 necess\u00e1rio manter a vigil\u00e2ncia dos ESAVI e das suspeitas de PAVV a fim de contribuir com a erradica\u00e7\u00e3o da poliomielite e a seguran\u00e7a da vacina\u00e7\u00e3o.<\/p>\n<\/sec>","DOI":"10.26633\/rpsp.2025.27","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T13:21:52Z","timestamp":1744204912000},"page":"1","source":"Crossref","is-referenced-by-count":2,"title":["Poliomielite associada ao v\u00edrus vacinal: seguran\u00e7a da vacina oral contra a poliomielite, Brasil, 2013-2023"],"prefix":"10.26633","volume":"49","author":[{"given":"Roberta Mendes Abreu","family":"Silva","sequence":"first","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."},{"name":"roberta.mendes@saude.gov.br"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Dinamerica","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano Ferreira","family":"Martins","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor Bertollo Gomes","family":"Porto","sequence":"additional","affiliation":[{"name":"Secretaria do Estado do Distrito Federal, Centro de Vigil\u00e2ncia Epidemiol\u00f3gica, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Catarina de Melo","family":"Araujo","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Henrique Santos","family":"Andrade","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha Elizabeth Brasil","family":"da N\u00f3brega","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cibelle Mendes","family":"Cabral","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f4nica Brauner","family":"de Moraes","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greice Madeleine","family":"Ikeda do Carmo","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe Daniel","family":"Cardoso","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade e Ambiente, Bras\u00edlia (DF), Brasil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme Alves","family":"de Siqueira","sequence":"additional","affiliation":[{"name":"Minist\u00e9rio da 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