{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:58:27Z","timestamp":1790614707425,"version":"4.1.0"},"reference-count":34,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,13]]},"abstract":"<title>RESUMEN<\/title>\n                  <p>HEARTS Farmacia, un proyecto que forma parte de la iniciativa HEARTS en las Am\u00e9ricas, proporciona un marco para integrar a profesionales de farmacia en la atenci\u00f3n primaria de salud. Los profesionales de farmacia son muy respetados en el \u00e1mbito de la atenci\u00f3n de salud, pero se enfrentan a diversos desaf\u00edos, como el alcance limitado de su labor, los obst\u00e1culos en la regulaci\u00f3n y un reconocimiento insuficiente, que se ven agravados por normas sociales que les impiden desarrollar todo su potencial. En este art\u00edculo se presenta evidencia convincente que indica que las intervenciones dirigidas por profesionales de farmacia mejoran el control de la presi\u00f3n arterial, disminuyen el riesgo cardiovascular y reducen los costos de la atenci\u00f3n de salud. Se subraya el papel de los sistemas nacionales de farmacia para garantizar el acceso a medicamentos de gran calidad. HEARTS Farmacia hace hincapi\u00e9 en el papel que desempe\u00f1an los profesionales de farmacia en la atenci\u00f3n en equipo, y destaca su competencia en el manejo de medicamentos, la educaci\u00f3n del paciente y la adherencia al tratamiento. En este art\u00edculo se aboga por cambios de pol\u00edtica que empoderen a los profesionales de farmacia d\u00e1ndoles mayor responsabilidad y que les permitan desempe\u00f1ar un papel activo en la atenci\u00f3n del paciente. Tambi\u00e9n se recomiendan medidas para la integraci\u00f3n plena de los profesionales de farmacia en los equipos de atenci\u00f3n, y para que sean un elemento clave en el control de la hipertensi\u00f3n y la gesti\u00f3n del riesgo de enfermedades cardiovasculares en la atenci\u00f3n primaria de salud.<\/p>","DOI":"10.26633\/rpsp.2026.35","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T14:22:50Z","timestamp":1776090170000},"page":"1","source":"Crossref","is-referenced-by-count":1,"title":["HEARTS Farmacia: marco para integrar a profesionales de farmacia en el manejo de la hipertensi\u00f3n y del riesgo de enfermedades cardiovasculares en la atenci\u00f3n primaria de salud*"],"prefix":"10.26633","volume":"50","author":[{"given":"Emily","family":"Ridley","sequence":"first","affiliation":[{"name":"https:\/\/orcid.org\/0000-0002-5043-1920"},{"name":"Departamento de Farmacia, Prisma Health, Columbia, Carolina del Sur, Estados Unidos de Am\u00e9rica."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald J.","family":"DiPette","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0000-0002-5762-9104"},{"name":"Departamento de Medicina, Facultad de Medicina de la Universidad de Carolina del Sur, Columbia, Carolina del Sur, Estados Unidos de Am\u00e9rica."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Gysel","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0009-0006-5706-4592"},{"name":"Apothecare Pharmacy, Calgary, Canad\u00e1."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Rosende","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0000-0001-8173-0686"},{"name":"Departamento de Enfermedades No Transmisibles y Salud Mental, Organizaci\u00f3n Panamericana de la Salud, Washington D.C., Estados Unidos de Am\u00e9rica."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norm R. C.","family":"Campbell","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0000-0002-1093-4742"},{"name":"Departamento de Medicina, Universidad de Calgary, Calgary, Canad\u00e1."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Neira Ojeda","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0000-0001-9133-8354"},{"name":"Departamento de Enfermedades No Transmisibles, Ministerio de Salud de Chile, Santiago de Chile, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Pesenti","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0009-0003-3699-4481"},{"name":"Confederaci\u00f3n Farmac\u00e9utica Argentina, Buenos Aires, Argentina."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma Consuelo","family":"Sanchez","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0009-0000-2369-4605"},{"name":"Hospital Comunitario San Ignacio, San Ignacio, Belice."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vilma","family":"Irazola","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0000-0002-6100-1862"},{"name":"Departamento de Investigaci\u00f3n en Enfermedades Cr\u00f3nicas, Instituto de Efectividad Cl\u00ednica y Sanitaria (IECS), Buenos Aires, Argentina."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Humberto","family":"Ruano Arevalo","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0009-0001-7506-336X"},{"name":"Direcci\u00f3n de Tecnolog\u00edas Sanitarias, Ministerio de Salud, San Salvador, El Salvador."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Paz","family":"L\u00f3pez Olivares","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0009-0004-2017-8831"},{"name":"Subdirecci\u00f3n de Gesti\u00f3n Asistencial, Direcci\u00f3n de Servicio de Salud Antofagasta, Antofagasta, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Cort\u00e9s Vidal","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0009-0007-2317-7684"},{"name":"Departamento de Gesti\u00f3n de la Atenci\u00f3n, Divisi\u00f3n de Atenci\u00f3n Primaria de Salud, Ministerio de Salud, Santiago de Chile, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mailin","family":"Beltran Delgado","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0000-0002-8234-0337"},{"name":"Departamento de Medicamentos y Tecnolog\u00edas M\u00e9dicas, Ministerio de Salud, La Habana, Cuba."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessenia","family":"Zurita","sequence":"additional","affiliation":[{"name":"Hospital Carlos Andrade Mar\u00edn, Quito, Ecuador."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Ordunez","sequence":"additional","affiliation":[{"name":"https:\/\/orcid.org\/0000-0002-9871-6845"},{"name":"ordunezp@paho.org"},{"name":"Departamento de Enfermedades No Transmisibles y Salud Mental, Organizaci\u00f3n Panamericana de la Salud, Washington D.C., Estados Unidos de Am\u00e9rica."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11167","reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Campbell NRC, Ordunez P, Giraldo G, Padwal R, Tsuyuki RT, Varghese C, et al. WHO HEARTS: A global program to reduce cardiovascular disease burden: experience implementing in the Americas and opportunities in Canada. Can J Cardiol. 2021 May;37(5):744-55. https:\/\/doi.org\/10.1016\/j.cjca.2020.12.004.","DOI":"10.1016\/j.cjca.2020.12.004"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Khan T, Moran AE, Perel P, Whelton PK, Brainin M, Feigin V, et al. The HEARTS partner forum\u2014supporting implementation of HEARTS to treat and control hypertension. Front Public Health. 2023 Jul 24;11:1146441. https:\/\/doi.org\/10.3389\/fpubh.2023.1146441.","DOI":"10.3389\/fpubh.2023.1146441"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Moran AE, Gupta R, Global Hearts Initiative Collaborators. Implementation of Global Hearts hypertension control programs in 32 low- and middle-income countries: JACC International. J Am Coll Cardiol. 2023 Nov 7;82(19):1868-84. https:\/\/doi.org\/10.1016\/j.jacc.2023.08.043.","DOI":"10.1016\/j.jacc.2023.08.043"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Ordunez P, Campbell NRC, Giraldo Arcila GP, Angell SY, Lombardi C, Brettler JW, et al. HEARTS en las Am\u00e9ricas: innovaciones para mejorar el manejo de la hipertensi\u00f3n y del riesgo cardiovascular en la atenci\u00f3n primaria. Rev Panam Salud Publica. 2022 Jul 16;46:e96. https:\/\/doi.org\/10.26633\/RPSP.2022.96.","DOI":"10.26633\/RPSP.2022.197"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Ordunez P, Campbell NRC, DiPette DJ, Jaffe MG, Rosende A, Martinez R, et al. HEARTS in the Americas: targeting health system change to improve population hypertension control. Curr Hypertens Rep. 2024 Apr;26(4):141-56. https:\/\/doi.org\/10.1007\/s11906-023-01286-w.","DOI":"10.1007\/s11906-023-01286-w"},{"key":"ref6","unstructured":"Organizaci\u00f3n Mundial de la Salud. Directriz para el tratamiento farmacol\u00f3gico de la hipertensi\u00f3n en adultos. Ginebra: OMS; 2021. https:\/\/www.who.int\/es\/publications\/i\/item\/9789240033986."},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Mills KT, Obst KM, Shen W, Molina S, Zhang HJ, He H, et al. Comparative effectiveness of implementation strategies for blood pressure control in hypertensive patients. Ann Int Med. 2018 Jan 16;168(2):110. https:\/\/doi.org\/10.7326\/m17-1805.","DOI":"10.7326\/M17-1805"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Tsuyuki RT, Houle SKD, Charrois TL, Kolber MR, Rosenthal MM, Lewanczuk R, et al. Randomized trial of the effect of pharmacist prescribing on improving blood pressure in the community. Circulation. 2015 Jul 14;132(2):93-100. https:\/\/doi.org\/10.1161\/circulationaha.115.015464.","DOI":"10.1161\/CIRCULATIONAHA.115.015464"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Tsuyuki RT, Al Hamarneh YN, Jones CA, Hemmelgarn BR. The effectiveness of pharmacist interventions on cardiovascular risk: the multicenter randomized controlled RxEACH trial. J Am Coll Cardiol. 2016 Jun 21;67(24):2846-54. https:\/\/doi.org\/10.1016\/j.jacc.2016.03.528.","DOI":"10.1016\/j.jacc.2016.03.528"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Victor RG, Lynch K, Li N, Blyler C, Muhammad E, Handler J, et al. A cluster-randomized trial of blood-pressure reduction in black barbershops. N Engl J Med. 2018 Apr 5;378(14):1291-301. https:\/\/doi.org\/10.1056\/NEJMoa1717250.","DOI":"10.1056\/NEJMoa1717250"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Mills KT, O\u2019Connell SS, Pan M, Obst KM, He H, He J. Role of health care professionals in the success of blood pressure control interventions in patients with hypertension: a meta-analysis. Circ Cardiovasc Qual Outcomes. 2024 Aug ;17(8):e010396. https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCOUTCOMES.123.010396.","DOI":"10.1161\/CIRCOUTCOMES.123.010396"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Matsumoto N, Nakai T, Sakakibara M, Aimiya Y, Suguira S, Lee JK, et al. Remote follow-up by pharmacists for blood pressure control in patients with hypertension: a systematic review and a meta-analysis of randomized controlled trials. Sci Rep. 2024 Jan 30;14(1). https:\/\/doi.org\/10.1038\/s41598-024-52894-8.","DOI":"10.1038\/s41598-024-52894-8"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Simpson SH, Majumdar SR, Tsuyuki RT, Lewanczuk RZ, Spooner R, Johnson JA. Effect of adding pharmacists to primary care teams on blood pressure control in patients with type 2 diabetes. Diabetes Care. 2011 Jan 1;34(1):20-6. https:\/\/diabetesjournals.org\/care\/article\/34\/1\/20\/27329\/Effect-of-Adding-Pharmacists-to-Primary-Care-Teams.","DOI":"10.2337\/dc10-1294"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Simpson SH, Lier DA, Majumdar SR, Tsuyutki RT, Lewanczuk RZ, Spooner R, et al. Cost\u2010effectiveness analysis of adding pharmacists to primary care teams to reduce cardiovascular risk in patients with Type 2 diabetes: results from a randomized controlled trial. Diabet Med. 2015 Jul ;32(7):899-906. https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/dme.12692.","DOI":"10.1111\/dme.12692"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Ip EJ, Shah BM, Yu J, Chan J, Nguyen LT, Bhatt DC. Enhancing diabetes care by adding a pharmacist to the primary care team. Am J Health Syst Pharm. 2013 May 15;70(10):877-86. https:\/\/doi.org\/10.2146\/ajhp120238.","DOI":"10.2146\/ajhp120238"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Al Hamarneh YN, Johnston K, Marra CA, Tsuyuki RT. Pharmacist prescribing and care improves cardiovascular risk, but is it cost-effective? A cost-effectiveness analysis of the RxEACH study. Can Pharm J (Ott). 2019 Jun 10;152(4):257-66. https:\/\/doi.org\/10.1177\/1715163519851822.","DOI":"10.1177\/1715163519851822"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Dixon DL, Johnston K, Patterson J, Marra CA, Tsuyuki RT. Cost-effectiveness of pharmacist prescribing for managing hypertension in the United States. JAMA Netw Open. 2023 Nov 3;;6(11):e2341408. https:\/\/doi.org\/10.1001\/jamanetworkopen.2023.41408.","DOI":"10.1001\/jamanetworkopen.2023.41408"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Dalton K, Byrne S. Role of the pharmacist in reducing healthcare costs: current insights. Integr Pharm Res Pract. 2017 Jan 1;6:37-46. https:\/\/doi.org\/10.2147\/iprp.s108047.","DOI":"10.2147\/IPRP.S108047"},{"key":"ref19","unstructured":"HEARTS Paquete t\u00e9cnico para el manejo de las enfermedades cardiovasculares en la atenci\u00f3n primaria de salud. Acceso a medicamentos y tecnolog\u00edas esenciales. Washington, D.C.: OPS; 2018 (OMS\/NMH\/NVI\/18.3). Disponible en: https:\/\/iris.paho.org\/handle\/10665.2\/50804."},{"key":"ref20","unstructured":"HEARTS. Paquete t\u00e9cnico para el manejo de las enfermedades cardiovasculares en la atenci\u00f3n primaria de salud: trabajo basado en equipos multidisciplinarios. Washington, D.C.: OPS; 2018 (WHO\/NMH\/ NVI\/18.4). Disponible en: https:\/\/iris.paho.org\/bitstream\/handle\/10665.2\/50855\/OPSNMH19004_spa.pdf."},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Neupane D, Gao Y, Feng Y, Matsushita K, Appel LJ. Estimation of the global gap in clinic visits for hypertension care between patient need and physician capacity. Hypertension. 2021 Aug 11;78(3):779-86. https:\/\/doi.org\/10.1161\/hypertensionaha.121.17660.","DOI":"10.1161\/HYPERTENSIONAHA.121.17660"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Brettler JW, Arcila GPG, Aumala T, Best A, Campbell NRC, Cyr S, et al. Drivers and scorecards to improve hypertension control in primary care practice: recommendations from the HEARTS in the Americas Innovation Group. Lancet Reg Health Am. 2022 May;9. https:\/\/doi.org\/10.1016\/j.lana.2022.100223.","DOI":"10.1016\/j.lana.2022.100223"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Rosende A, DiPette D, Brettler J, Rodr\u00edguez G, Zuniga E, Connell K, et al. HEARTS in the Americas appraisal checklist and clinical pathway for comprehensive hypertension management in primary care. Rev Panam Salud Publica. 2022;46:e125. https:\/\/doi.org\/10.26633\/RPSP.2022.125","DOI":"10.26633\/RPSP.2022.125"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Souza KM, Giron N, Vallini J, Hallar K, Ordunez P, Rosende A, et al. Barriers to access to antihypertensive medicines: insights from the HEARTS initiative in Latin American and Caribbean region. J Pharm Policy Pract. 2024 Aug 5;17(1). https:\/\/doi.org\/10.1080\/20523211.2024.2379045.","DOI":"10.1080\/20523211.2024.2379045"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Cohn J, Bygrave H, Roberts T, Khan T, Ojji D, Ordunez P. Addressing failures in achieving hypertension control in low- and middle-income settings through simplified treatment algorithms. Glob Heart. 2022 Jan 1;17(1). https:\/\/doi.org\/10.5334\/gh.1082.","DOI":"10.5334\/gh.1082"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Giron N, Lim C, Vallini J, Hallar K. Avanzando para mejorar el acceso a los medicamentos y tecnolog\u00edas sanitarias para las enfermedades cardiovasculares. Rev Panam Salud Publica. 2022;46:e156. https:\/\/doi.org\/10.26633\/RPSP.2022.156","DOI":"10.26633\/RPSP.2022.156"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"DiPette DJ, Skeete J, Ridley E, Campbell NRC, Lopez-Jaramillo P, Kishore SP, et al. Fixed\u2010dose combination pharmacologic therapy to improve hypertension control worldwide: clinical perspective and policy implications. J Clin Hypertens. 2019 Jan 10;21(1):4-15. https:\/\/doi.org\/10.1111\/jch.13426.","DOI":"10.1111\/jch.13426"},{"key":"ref28","unstructured":"Health Product Policy and Standards (HPS). TRS 1025 - 54th report of the WHO Expert Committee on Specifications for Pharmaceutical Preparations [Internet]; 2020. Disponible en: https:\/\/www.who.int\/publications\/i\/item\/978-92-4-000182-4."},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Flood D, Edwards EW, Giovannini D, Ridley E, Rosende A, Herman WH, et al. HEARTS como herramienta para integrar el manejo de la hipertensi\u00f3n y la diabetes en los entornos de atenci\u00f3n primaria de salud. Rev Panam Salud Publica. 2022;46:e213. https:\/\/doi.org\/10.26633\/RPSP.2022.213","DOI":"10.26633\/RPSP.2022.213"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Kadia NK, Schroeder MN. Community pharmacy-based adherence programs and the role of pharmacy technicians. J Pharm Tech. 2015 Feb 12;31(2):51-7. https:\/\/doi.org\/10.1177\/8755122515572809.","DOI":"10.1177\/8755122515572809"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Rajiah K, Sivarasa S, Maharajan MK. Impact of pharmacists\u2019 interventions and patients\u2019 decision on health outcomes in terms of medication adherence and quality use of medicines among patients attending community pharmacies: a systematic review. Int J Environ Res Public Health. 2021 Apr 21;18(9):4392. https:\/\/doi.org\/10.3390\/ijerph18094392.","DOI":"10.3390\/ijerph18094392"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Reeves L, Robinson K, McClelland T, Adedoyin CA, Broeseker A, Adunlin G. Pharmacist interventions in the management of blood pressure control and adherence to antihypertensive medications: a systematic review of randomized controlled trials. J Pharm Pract. 2020 Feb 18;34(3):480-92. https:\/\/doi.org\/10.1177\/0897190020903573.","DOI":"10.1177\/0897190020903573"},{"key":"ref33","doi-asserted-by":"crossref","unstructured":"Lim R, Bilton R, Dorj G, Bereznicki L, Rowett D, Ho JN, et al. Pharmacists as patient advocates: a series of case studies illustrating the impacts of a regular pharmacist service in residential aged care (nursing homes). Explor Res Clin Soc Pharm. 2023 June ;10:100268. https:\/\/doi.org\/10.1016\/j.rcsop.2023.100268.","DOI":"10.1016\/j.rcsop.2023.100268"},{"key":"ref34","unstructured":"Division of Epidemiology, Analysis and Data Visualization. State of the heart: heart disease in South Carolina [Internet]. South Carolina Department of Public Health; 2023 [consultado el 18 de noviembre del 2024]. Disponible en: https:\/\/dc.statelibrary.sc.gov\/entities\/publication\/aa720f04-fe57-4f42-a64c-6d809fde18d5."}],"container-title":["Revista Panamericana de Salud P\u00fablica"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/iris.paho.org\/bitstreams\/6fd40b52-5619-4037-9e65-bb74272f6be8\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T14:23:07Z","timestamp":1776090187000},"score":1,"resource":{"primary":{"URL":"https:\/\/iris.paho.org\/handle\/10665.2\/71053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,13]]},"references-count":34,"alternative-id":["RPSP.2026.35"],"URL":"https:\/\/doi.org\/10.26633\/rpsp.2026.35","relation":{},"ISSN":["1020-4989","1680-5348"],"issn-type":[{"value":"1020-4989","type":"print"},{"value":"1680-5348","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,13]]}}}