{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:49:16Z","timestamp":1791474556611,"version":"4.3.4"},"reference-count":30,"publisher":"Pan American Health Organization","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,8]]},"abstract":"<title>RESUMEN<\/title>\n                  <sec>\n                    <title>Objetivo.<\/title>\n                    <p>Analizar los factores sociodemogr\u00e1ficos asociados a la letalidad de los casos de fiebre amarilla en Colombia entre enero del 2024 y enero del 2026.<\/p>\n                  <\/sec>\n                  <sec>\n                    <title>M\u00e9todos.<\/title>\n                    <p>Se realiz\u00f3 un estudio observacional anal\u00edtico de cohorte retrospectiva basado en registros del Sistema Nacional de Vigilancia en Salud P\u00fablica (SIVIGILA). Se incluyeron casos probables y confirmados de fiebre amarilla notificados entre el 1 de enero del 2024 y el 31 de enero de 2026. Las variables cuantitativas se describieron mediante la mediana y el rango intercuart\u00edlico, y las categ\u00f3ricas mediante frecuencias absolutas y relativas. La supervivencia acumulada se estim\u00f3 mediante curvas de Kaplan-Meier y los factores asociados a letalidad se evaluaron mediante modelos de riesgos proporcionales de Cox.<\/p>\n                  <\/sec>\n                  <sec>\n                    <title>Resultados.<\/title>\n                    <p>Se incluyeron 164 casos, con predominio de hombres y una mediana de edad de 45 a\u00f1os. Se registraron 70 muertes atribuibles a fiebre amarilla, con una letalidad del 42,7%, con marcada concentraci\u00f3n territorial en el departamento del Tolima y mayor afectaci\u00f3n en hombres, adultos mayores y personas vinculadas a actividades agropecuarias. La edad de 60 a\u00f1os o m\u00e1s se asoci\u00f3 con un mayor riesgo de muerte (HR ajustado = 5,45; IC95%: 1,13-26,2).<\/p>\n                  <\/sec>\n                  <sec>\n                    <title>Conclusiones.<\/title>\n                    <p>La fiebre amarilla present\u00f3 una alta letalidad entre los casos notificados como probables y confirmados en Colombia, especialmente en adultos mayores. Los hallazgos respaldan la necesidad de fortalecer las estrategias de vacunaci\u00f3n, vigilancia epidemiol\u00f3gica y detecci\u00f3n temprana en territorios con circulaci\u00f3n activa del virus.<\/p>\n                  <\/sec>","DOI":"10.26633\/rpsp.2026.92","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:49:26Z","timestamp":1791470966000},"page":"1","source":"Crossref","is-referenced-by-count":0,"title":["Factores sociodemogr\u00e1ficos asociados a letalidad por fiebre amarilla en Colombia, 2024-2026"],"prefix":"10.26633","volume":"50","author":[{"given":"Heriberto","family":"V\u00e1squez-Serna","sequence":"first","affiliation":[{"name":"Direcci\u00f3n de Epidemiolog\u00eda y Demograf\u00eda, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alexander","family":"Huertas-Caro","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n de Epidemiolog\u00eda y Demograf\u00eda, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."},{"name":"cejimenezc@ut.edu.co"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Urrego-Ricaurte","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n de Epidemiolog\u00eda y Demograf\u00eda, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan Estiven","family":"Vargas-Vargas","sequence":"additional","affiliation":[{"name":"Grupo de investigaci\u00f3n ENOCARDIO +, Universidad del Tolima, Ibagu\u00e9, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam Andrea","family":"Ruiz Dionisio","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n de Prestaci\u00f3n de servicios y Atenci\u00f3n Primaria, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Octavio","family":"Henao Orrego","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n de Prestaci\u00f3n de servicios y Atenci\u00f3n Primaria, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Chaparro-Narv\u00e1ez","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n de Prestaci\u00f3n de servicios y Atenci\u00f3n Primaria, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nataly","family":"B\u00e1ez Cortes","sequence":"additional","affiliation":[{"name":"Observatorio Nacional de Salud, Instituto Nacional de Salud Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio Javier","family":"Vera Soto","sequence":"additional","affiliation":[{"name":"Grupo Gesti\u00f3n Integrada de Enfermedades Endemoepid\u00e9micas, Direcci\u00f3n de Promoci\u00f3n y Prevenci\u00f3n, Subdirecci\u00f3n de Enfermedades Transmisibles, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Montenegro","sequence":"additional","affiliation":[{"name":"Grupo Gesti\u00f3n Integrada de Enfermedades Endemoepid\u00e9micas, Direcci\u00f3n de Promoci\u00f3n y Prevenci\u00f3n, Subdirecci\u00f3n de Enfermedades Transmisibles, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Eduardo","family":"Jim\u00e9nez Canizales","sequence":"additional","affiliation":[{"name":"Direcci\u00f3n de Epidemiolog\u00eda y Demograf\u00eda, Ministerio de Salud y Protecci\u00f3n Social, Bogot\u00e1, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11167","reference":[{"key":"ref1","unstructured":"Organizaci\u00f3n Panamericana de la Salud. 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