{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T22:29:04Z","timestamp":1786487344930,"version":"build-2736575974"},"reference-count":0,"publisher":"Pasifika Medical Association Group","issue":"1640","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NZMJ"],"abstract":"<jats:p>Status epilepticus (SE) is a life-threatening neurological emergency defined by continuous seizure activity longer than 5 minutes or\nby clustered seizures without recovery of consciousness. When SE persists for over 30 minutes it is associated with irreversible brain\ndamage. Conversely, most seizures are self-limited and do not require pharmacological treatment, while some seizures may not be\nepileptic. The risk of overtreating such cases must, therefore, be carefully balanced against the risk of under-recognising and undertreating\nSE. An acquired severe brain injury (e.g., traumatic or stroke) significantly increases the risk of developing seizures, SE and\nepilepsy. Poor prognostic signs include major brain injury, longer duration of seizures and treatment resistance. There is a gap between\nclinical practice guidelines (CPGs) for the management of SE and actual clinical practice. Delayed and timid (under-dose) treatments\ncontribute to the perpetuation of SE. A multidisciplinary approach, including early treatment with adequate doses of benzodiazepines\n(e.g., midazolam) with second-line treatment (e.g., levetiracetam) are key in improving clinical outcomes. Located in the exact antipode\nof the Manawat\u016b Gorge, Hospital Universitario Los Madro\u00f1os is a medium-size centre known for its neurorehabilitation unit\nwhere we have adopted SE CPGs from Palmerston North Hospital and adapted them to local needs and resources, promoting early\nintervention and staff familiarity. A pragmatic, consensus-based, site-specific algorithm helps reduce treatment delays and improves\nclinical outcomes, providing a viable solution to bridge care gaps.<\/jats:p>","DOI":"10.26635\/6965.7280","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T21:50:14Z","timestamp":1786485014000},"page":"87-95","source":"Crossref","is-referenced-by-count":0,"title":["Drilling a hole to shorten the gap: an Aotearoa New Zealand therapeutic algorithm for status epilepticus in NEUROPA (Madrid, Spain)"],"prefix":"10.26635","volume":"139","author":[{"given":"Ivan","family":"Iniesta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almond","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Rodriguez Pe\u00f1a-Marin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Caballero Cubedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chissolle","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11177","published-online":{"date-parts":[[2026,8,14]]},"container-title":["New Zealand Medical Journal"],"original-title":[],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T21:50:17Z","timestamp":1786485017000},"score":1,"resource":{"primary":{"URL":"https:\/\/nzmj.org.nz\/journal\/vol-139-no-1640\/drilling-a-hole-to-shorten-the-gap-an-aotearoa-new-zealand-therapeutic-algorithm-for-status-epilepticus-in-neuropa-madrid-spain"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,14]]},"references-count":0,"journal-issue":{"issue":"1640","published-online":{"date-parts":[[2026,8,14]]}},"URL":"https:\/\/doi.org\/10.26635\/6965.7280","relation":{},"ISSN":["1175-8716"],"issn-type":[{"value":"1175-8716","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,14]]}}}