{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T04:54:51Z","timestamp":1771649691932,"version":"3.50.1"},"reference-count":26,"publisher":"Kurume Medical Journal","issue":"3\/4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kurume Med. J."],"published-print":{"date-parts":[[2009]]},"DOI":"10.2739\/kurumemedj.56.39","type":"journal-article","created":{"date-parts":[[2010,5,26]],"date-time":"2010-05-26T06:04:47Z","timestamp":1274853887000},"page":"39-47","source":"Crossref","is-referenced-by-count":10,"title":["Effects of Cevimeline on the Immunolocalization of Aquaporin-5 and the Ultrastructure of Salivary Glands in Sj\u00f6gren\u2019s Syndrome Model Mice"],"prefix":"10.2739","volume":"56","author":[{"given":"HIDEHIKO","family":"NISHIMURA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AKIRA","family":"YAKEISHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TSUYOSHI","family":"SAGA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"KOH-ICHI","family":"YAMAKI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1445","reference":[{"key":"1","unstructured":"1. Arisawa H, Imai E, Fujise N, Fukui K, and Masunaga H. General pharmacological profile of the novel muscarinic receptor agonist SNI-2011, a drug for xerostomia in Sj&ouml;gren&rsquo;s syndrome. Arzneim Forsch Drug Res 2002; 52:14-20."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Fife RS, Chase WF, Dore RK, Wiesenhutter CW, Lockhart PB et al. Cevimeline for the treatment of xerostomia in patients with Sj&ouml;gren&rsquo;s syndrome. Arch Intern Med 2002; 162:1293-1300.","DOI":"10.1001\/archinte.162.11.1293"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/art.510"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780270206"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1988.tb01316.x"},{"issue":"8","key":"6","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1440-1827.1994.tb01716.x","volume":"44","author":"HAYAHSHI Y","year":"1994","ISSN":"https:\/\/id.crossref.org\/issn\/1320-5463","issn-type":"print"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.78.373"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(97)01338-1"},{"key":"9","unstructured":"9. Washio T, Kohsaka K, Arisawa H, and Masunaga H. Pharmacokinetics and metabolism of the novel muscarinic receptor agonist SNI-2011 in rats and dogs. Arzneim Forsch Drug Res 2003; 53:26-33."},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092140304"},{"issue":"1","key":"11","first-page":"3","volume":"30","author":"FIRAT D","year":"2002","ISSN":"https:\/\/id.crossref.org\/issn\/0385-1443","issn-type":"print"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s11282-006-0037-8"},{"issue":"36","key":"13","doi-asserted-by":"crossref","first-page":"17497","DOI":"10.1016\/S0021-9258(18)45408-7","volume":"262","year":"1987","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.4.1908"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s004410051257"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.29.20071"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M008760200"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Gresz V, Kwon TH, Gong H, Agre P, Steward MC et al. Immunolocalization of AQP-5 in rat parotid and submandibular salivary glands after stimulation or inhibition of secretion in vivo. Am J Physiol Gastro 2004; 287:G151-G161.","DOI":"10.1152\/ajpgi.00480.2003"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Ishikawa Y, Yuan Z, Inoue N, Skowronski MT, Nakae Y et al. Identification of AQP5 in lipid rafts and its translocation to apical membranes by activation of M3 mA ChRs in interlobular ducts of rat parotid gland. Am J Physiol Cell Physiol 2005; 289:1303-1311.","DOI":"10.1152\/ajpcell.00211.2005"},{"key":"20","unstructured":"20. Konttinen YT, Tensing EK, Laine M, Porola P, T&ouml;rnwall J et al. Abnormal distribution of aquaporin-5 in salivary glands in the NOD mouse model for Sj&ouml;gren&rsquo;s syndrome. J Rheum 2005; 32:1071-1075."},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Basu MK, Price JD, and Matthews JB. Benign lymphoepithelial lesion in a patient with Sj&ouml;gren&rsquo;s disease and an IgG paraprotein. J Oral Pathol 1983; 12:515-526.","DOI":"10.1111\/j.1600-0714.1983.tb00363.x"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Cutler LS, Bullis D, Christian CP, Rendell JR, and Greiner DL. Animal models of Sj&ouml;gren&rsquo;s syndrome. J Dent Res 1987; 66:590-591.","DOI":"10.1177\/00220345870660023701"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1007\/s00795-004-0246-3"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Steinfeld S, Cogan E, King LS, Agre P, Kiss R et al. Abnormal distribution of aquaporin-5 water channel protein in salivary glands from Sj&ouml;gren&rsquo;s syndrome patients. Lab Invest 2001; 81:143-148.","DOI":"10.1038\/labinvest.3780221"},{"key":"25","unstructured":"25. Iwabuchi Y, Katagiri M, and Masuhara T. Salivary secretion and histopathological effects after single administration of the muscarinic agonist SNI-2011 in MRL\/lpr mice. Arch Int Pharmacodyn 1994; 328:315-325. (in Japanese)"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Kumegawa M, Cattoni M, and Rose GG. An unusual droplet in submandibular gland of new born mice. J Cell Biol 1967; 33:720-723.","DOI":"10.1083\/jcb.33.3.720"}],"container-title":["The Kurume Medical Journal"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,10,28]],"date-time":"2021-10-28T07:38:08Z","timestamp":1635406688000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/kurumemedj\/56\/3+4\/56_3+4_39\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"references-count":26,"journal-issue":{"issue":"3\/4","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.2739\/kurumemedj.56.39","relation":{},"ISSN":["0023-5679","1881-2090"],"issn-type":[{"value":"0023-5679","type":"print"},{"value":"1881-2090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009]]}}}