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Nakamura S. The actual condition of medical examination: drymouth. Jpn J Clinical and Experimental Medicine 2007; 84:939-946. (in Japanese)"},{"key":"2","unstructured":"2. Akizuki M. Sjögren’s syndrome. Jpn Med J 1992; 3542:30-34. (in Japanese)"},{"key":"3","unstructured":"3. Arisawa H, Imai E, Fujise N, Fukui K, and Masunaga H. General pharmacological profile of the novel muscarinic receptor agonist SNI-2011, a drug for xerostomia in Sjögren’s syndrome. Arzneim.-Forsch.\/Drug Res 2002; 52:14-20."},{"key":"4","unstructured":"4. Kashiwazaki S, Ichikawa Y, Torikai K, Kondo H, Miyawaki S et al. Examination of the dose increase method about the effectiveness and the safety of SNI-2011 against drymouth in sjögren’s syndrome patients. Med Consult New Remedies 2001; 38:313-332. (in Japanese)."},{"key":"5","unstructured":"5. Ichikawa Y, Kashiwazaki S, Hara M, Torikai K, Kondo H et al. 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Akamatu T, Parvin MN, Murdiastuti K, Tanaka C, Yao C et al. Expression and localization of aquaporins, members of the water channel family, during development of the rat submandibular gland. Eur J Physiol 2003; 446:641-651.","DOI":"10.1007\/s00424-003-1109-9"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Ma T, Song Y, Gillespie A, Carlson EJ, Epstein CJ et al. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. J Biol Chem 1999; 274:20071-20074.","DOI":"10.1074\/jbc.274.29.20071"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Krane CM, Melvin JE, Nguyen HV, Richardson L, Towne JE et al. Salivary acinar cells from aquaporin 5-deficient mice have decreased membrane water permeability and altered cell volume regulation. J Biol Chem 2001; 276:23413-23420.","DOI":"10.1074\/jbc.M008760200"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Hayashi Y, Haneji N and Hamano H. 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