{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:53:19Z","timestamp":1793692399530,"version":"4.5.1"},"reference-count":27,"publisher":"Kurume Medical Journal","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kurume Med. J."],"published-print":{"date-parts":[[2018,12,31]]},"DOI":"10.2739\/kurumemedj.ms654002","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T18:02:57Z","timestamp":1565200977000},"page":"137-144","source":"Crossref","is-referenced-by-count":28,"title":["Neuroprotective Effects of Ozone Therapy After Sciatic Nerve Cut Injury"],"prefix":"10.2739","volume":"65","author":[{"given":"EREN","family":"OGUT","sequence":"first","affiliation":[{"name":"Department of Anatomy, Faculty of Medicine, Bahcesehir University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FATOS BELGIN","family":"YILDIRIM","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Akdeniz University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LEVENT","family":"SARIKCIOGLU","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Akdeniz University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MUTAY ASLAN","family":"AYDIN","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Akdeniz University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NECDET","family":"DEM\u0130R","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Medicine, Akdeniz University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1445","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Dagum AB. Peripheral nerve regeneration, repair, and grafting. J Hand Ther. 1998; 11(2):111-7.","DOI":"10.1016\/S0894-1130(98)80007-0"},{"key":"2","unstructured":"2. Winograd JM, Mackinnon SE. Peripheral nevre injuries: Repair and reconstruction, in Plastic surgery, I.M. SJ, Editor. 2006, Saunders Elsevier: Philadelphia. p. 47-514."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Dahlin LB. The biology of nerve injury and repair. J Am Surg Hand. 2004; 4(3):143-55.","DOI":"10.1016\/j.jassh.2004.06.006"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Terenghi G. Peripheral nerve regeneration and neurotrophic factors. J Anat. 1999; 194 (1):1-14.","DOI":"10.1046\/j.1469-7580.1999.19410001.x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Glickman LT, Mackinnon SE. Sensory recovery following digital replantation. Microsurgery. 1990; 11(3):236-42.","DOI":"10.1002\/micr.1920110311"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Ozbay I, Ital I, Kucur C, Akcilar R, Deger A, Aktas S, Oghan F. Effects of ozone therapy on facial nerve regeneration. Braz. J Otorhinolaryngol. 2016; 83(2):168-175.","DOI":"10.1016\/j.bjorl.2016.02.009"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Yuce S, et al. An experimental comparison of the effects of propolis, curcumin, and methylprednisolone on crush injuries of the sciatic nerve. Ann Plast Surg. 2015; 74(6):684-92.","DOI":"10.1097\/SAP.0000000000000026"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Thomas DA, Ren K, Besse D, Ruda MA, Dubner R. Application of nitric oxide synthase inhibitor, N omega-nitro-l-arginine methylester, on injured nerve attenuates neuropathy-induced thermalhyperalgesia in rats. Neurosci Lett. 1996; (210):124-6.","DOI":"10.1016\/0304-3940(96)12670-7"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Papucci L, et al. Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property. J Biol Chem. 2003; 278(30):28220-8.","DOI":"10.1074\/jbc.M302297200"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Wells KH, et al. Inactivation of human immunodeficiency virus type 1 by ozone in vitro. Blood. 1991; 78(7):1882-90.","DOI":"10.1182\/blood.V78.7.1882.1882"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Holz O, et al. Validation of the human ozone challenge model as a tool for assessing anti-inflammatory drugs in early development. J Clin Pharmacol. 2005; 45(5):498-503.","DOI":"10.1177\/0091270004273527"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Candelario-Jalil E, Mohammed-Al-Dalain S, Fernandez OS, Menendez S, Perez-Davison G, Merino N, et al. Oxidative preconditioning affords protection against carbontetrachloride induced glycogen depletion and oxidative stress in rats. J Appl Toxicol. 2001; 21:291-301.","DOI":"10.1002\/jat.758"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Droge W. Free radicals in the physiological control of cell function. Physiol Rev. 2002; 82(1):47-95.","DOI":"10.1152\/physrev.00018.2001"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Al-Dalain SM, et al. Ozone treatment reduces markers of oxidative and endothelial damage in an experimental diabetes model in rats. Pharmacol Res. 2001; 44(5):391-6.","DOI":"10.1006\/phrs.2001.0867"},{"key":"15","unstructured":"15. Batinjan G, et al. The use of ozone in the prevention of osteoradionecrosis of the jaw. Saudi Medical Journal. 2014; 35(10):1260-1263."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Bocci V, Aldinucci C. Biochemical modifications induced in human blood by oxygenation-ozonation. Journal of Biochemical and Molecular Toxicology. 2006; 20(3):133-138.","DOI":"10.1002\/jbt.20124"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Bain JR, Mackinnon SE, Hunter DA. Functional-Evaluation of Complete Sciatic, Peroneal and Posterior Tibial Nerve Lesions in the Rat. Plastic and Reconstructive Surgery. 1989; 83(1):129-136.","DOI":"10.1097\/00006534-198901000-00024"},{"key":"18","unstructured":"18. Yilmaz Z, et al. Neuroprotective Effects of Mannitol And Vitamin C on Crush Injury of Sciatic Nerve; An Experimental Rat Study. Journal of Neurological Sciences-Turkish. 2011; 28(4):538-551."},{"key":"19","unstructured":"19. Bocci V.Ozone-A new medical drug. 2005, Dordrecht: Springer."},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Lin Q, et al. Effects of ozone on sciatic nerve in rat. Interv Neuroradiol. 2011; 17(3):281-5.","DOI":"10.1177\/159101991101700301"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Somay H, et al. The Histological Effects of Ozone Therapy on Sciatic Nerve Crush Injury in Rats. World Neurosurg. 2017; 105:702-708.","DOI":"10.1016\/j.wneu.2017.05.161"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Travagli V, Zanardi I, Silvietti A, Bocci V. A physicochemical investigation on the effects of ozone on blood. International Journal of Biological Macromolecules. 2007; 41(5):504-511.","DOI":"10.1016\/j.ijbiomac.2007.06.010"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Romero FJ, et al. Oxygen toxicity in the nervous tissue: comparison f the antioxidant defense rat brain and sciatic nerve. Neurochem Res. 1991; 16(2):157-161.","DOI":"10.1007\/BF00965704"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Vogelaar CF, et al. Sciatic nerve regeneration in mice and rats: recovery of sensory innervation is followed by a slowly retreating neuropathic pain-like syndrome. Brain Research. 2004; 1027(1-2):67-72.","DOI":"10.1016\/j.brainres.2004.08.036"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Souza YM, et al. Evaluation of the effects of ozone therapy in the treatment of intra-abdominal infection in rats. Clinics (Sao Paulo). 2010; 65(2):195-202.","DOI":"10.1590\/S1807-59322010000200012"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Gupta R, Steward O. Chronic nerve compression induces concurrent apoptosis and proliferation of Schwann cells. J Comp Neurol. 2003; 461(2):174-86.","DOI":"10.1002\/cne.10692"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Dianzani MU. 4-hydroxynonenal from pathology to physiology. Mol Asp. Med.2003; 24(4-5):263-72.","DOI":"10.1016\/S0098-2997(03)00021-9"}],"container-title":["The Kurume Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/kurumemedj\/65\/4\/65_MS654002\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T23:12:35Z","timestamp":1579907555000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/kurumemedj\/65\/4\/65_MS654002\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,31]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.2739\/kurumemedj.ms654002","relation":{},"ISSN":["0023-5679","1881-2090"],"issn-type":[{"value":"0023-5679","type":"print"},{"value":"1881-2090","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,31]]}}}