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Radcliffe R and Nemerson Y. Activation and control of factor VII by activated factor X and thrombin. Isolation and characterization of a single chain form of factor VII. J Biol Chem 1975; 250(2):388-395.","DOI":"10.1016\/S0021-9258(19)41912-1"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Neuenschwander PF, Fiore MM, and Morrissey JH. Factor VII autoactivation proceeds via interaction of distinct protease-cofactor and zymogen-cofactor complexes. Implications of a two-dimensional enzyme kinetic mechanism. J Biol Chem 1993; 268(29):21489-21492.","DOI":"10.1016\/S0021-9258(20)80565-1"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Butenas S and Mann KG. Kinetics of human factor VII activation. Biochemistry 1996; 35(6):1904-1910.","DOI":"10.1021\/bi951768c"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Osterud B and Rapaport SI. Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation. Proc Natl Acad Sci USA 1977; 74(12):5260-5264.","DOI":"10.1073\/pnas.74.12.5260"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Bauer KA, Kass BL, ten Cate H, Hawiger JJ, and Rosenberg RD. Factor IX is activated in vivo by the tissue factor mechanism. Blood 1990; 76(4):731-736.","DOI":"10.1182\/blood.V76.4.731.731"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Pfeiffer RA, Ott R, Gilgenkrantz S, and Alexandre P. Deficiency of coagulation factors VII and X associated with deletion of a chromosome 13 (q34). Evidence from two cases with 46,XY,t(13;Y)(q11;q34). Hum Genet 1982; 62(4):358-360.","DOI":"10.1007\/BF00304557"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. O\u2019Hara PJ, Grant FJ, Haldeman BA, Gray CL, Insley MY et al. Nucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulation. Proc Natl Acad Sci USA 1987; 84(15):5158-5162.","DOI":"10.1073\/pnas.84.15.5158"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J et al. Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res 2001; 11(5):677-684.","DOI":"10.1101\/gr.164001"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Pollak ES, Hung HL, Godin W, Overton GC and High KA. Functional characterization of the human factor VII 5\u2019-flanking region. J Biol Chem 1996; 271(3):1738-1747.","DOI":"10.1074\/jbc.271.3.1738"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Peyvandi F, Menegatti M and Palla R. Rare bleeding disorders: worldwide efforts for classification, diagnosis, and management. Semin Thromb Hemost 2013; 39(6):579-584.","DOI":"10.1055\/s-0033-1349221"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Mannucci PM and Tuddenham EG. The hemophilias--from royal genes to gene therapy. N Engl J Med 2001; 344(23):1773-1779.","DOI":"10.1056\/NEJM200106073442307"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Mariani G, Herrmann FH, Dolce A, Batorova A, Etro D et al. Clinical phenotypes and factor VII genotype in congenital factor VII deficiency. Thromb Haemost 2005; 93(3):481-487.","DOI":"10.1160\/TH04-10-0650"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Napolitano M, Di Minno MN, Batorova A, Dolce A, Giansily-Blaizot M et al. Women with congenital factor VII deficiency: clinical phenotype and treatment options from two international studies. Haemophilia 2016; 22(5):752-759.","DOI":"10.1111\/hae.12978"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Beroud C, Hamroun D, Collod-Beroud G, Boileau C, Soussi T et al. UMD (Universal Mutation Database): 2005 update. Hum Mutat 2005; 26(3):184-191.","DOI":"10.1002\/humu.20210"},{"key":"15","unstructured":"15. The F7 mutations database [updated 18\/08\/18 Available from: http:\/\/www.umd.be\/F7\/W_F7\/index.html."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Hewitt J, Ballard JN, Nelson TN, Smith VC, Griffiths TA et al. Severe FVII deficiency caused by a new point mutation combined with a previously undetected gene deletion. Br J Haematol 2005; 128(3):380-385.","DOI":"10.1111\/j.1365-2141.2004.05296.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Cooper DN, Millar DS, Wacey A, Banner DW, and Tuddenham EG. Inherited factor VII deficiency: molecular genetics and pathophysiology. Thromb Haemost 1997; 78(1):151-160.","DOI":"10.1055\/s-0038-1657519"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Giansily-Blaizot M, Aguilar-Martinez P, Biron-Andreani C, Jeanjean P, Igual H et al. Analysis of the genotypes and phenotypes of 37 unrelated patients with inherited factor VII deficiency. Eur J Hum Genet 2001; 9(2):105-112.","DOI":"10.1038\/sj.ejhg.5200593"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Arbini AA, Pollak ES, Bayleran JK, High KA, and Bauer KA. Severe factor VII deficiency due to a mutation disrupting a hepatocyte nuclear factor 4 binding site in the factor VII promoter. Blood 1997; 89(1):176-182.","DOI":"10.1182\/blood.V89.1.176"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Ozawa T, Takikawa Y, Niiya K, Ejiri N, Suzuki K et al. Factor VII Morioka (FVII L-26P): a homozygous missense mutation in the signal sequence identified in a patient with factor VII deficiency. Br J Haematol 1998; 101(1):47-49.","DOI":"10.1046\/j.1365-2141.1998.00666.x"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. 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Sladek FM, Zhong WM, Lai E, and Darnell JE Jr. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev 1990; 4(12B):2353-2365.","DOI":"10.1101\/gad.4.12b.2353"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Erdmann D and Heim J. Orphan nuclear receptor HNF-4 binds to the human coagulation factor VII promoter. J Biol Chem 1995; 270(39):22988-22996.","DOI":"10.1074\/jbc.270.39.22988"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Carew JA, Pollak ES, Lopaciuk S, and Bauer KA. A new mutation in the HNF4 binding region of the factor VII promoter in a patient with severe factor VII deficiency. Blood 2000; 96(13):4370-4372.","DOI":"10.1182\/blood.V96.13.4370.h8004370_4370_4372"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Kavlie A, Hiltunen L, Rasi V, and Prydz H. Two novel mutations in the human coagulation factor VII promoter. 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