{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:16:59Z","timestamp":1763036219220,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,1,5]],"date-time":"2010-01-05T00:00:00Z","timestamp":1262649600000},"content-version":"vor","delay-in-days":2196,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Reasons for performing study<\/jats:italic>\n                    : To present the first report of a case series concerning equine idiopathic muscular hypertrophy of the oesophagus (IMHO).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Objectives<\/jats:italic>\n                    : To investigate the clinical and pathological features of the disorder.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Methods<\/jats:italic>\n                    : The medical records of 31 horses suffering from the disorder were reviewed retrospectively. In all these animals the diagnosis was confirmed at\n                    <jats:italic>post mortem<\/jats:italic>\n                    examination.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    : The median age of the affected horses was 12.5 \u00b1 5.6 years (range 1\u201326) without sex or breed predilection. Only 2 out of 31 horses showed clinical signs associated with oesophageal dysfunction, indicating that the muscular hypertrophy was rather a coincidental\n                    <jats:italic>post mortem<\/jats:italic>\n                    finding. Histology revealed thickening of the distal portion of the oesophagus mainly involving the circular layer of the\n                    <jats:italic>tunica muscularis<\/jats:italic>\n                    without fibrosis or inflammation. In 8 cases, the disorder was seen in concurrence with idiopathic hypertrophy of the\n                    <jats:italic>tunica muscularis<\/jats:italic>\n                    of various other parts of the gastrointestinal tract.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions<\/jats:italic>\n                    : In the majority of patients, IMHO was a coincidental finding at\n                    <jats:italic>post mortem<\/jats:italic>\n                    examination usually confined to the smooth, circular muscle layer of the\n                    <jats:italic>tunica muscularis externa.<\/jats:italic>\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Potential relevance<\/jats:italic>\n                    : Further research is necessary to study the precise effect of IMHO on oesophageal function.\n                  <\/jats:p>","DOI":"10.2746\/0425164044864697","type":"journal-article","created":{"date-parts":[[2007,4,12]],"date-time":"2007-04-12T19:03:27Z","timestamp":1176404607000},"page":"46-50","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Idiopathic muscular hypertrophy of the oesophagus in the horse: a retrospective study of 31 cases"],"prefix":"10.1111","volume":"36","author":[{"given":"N. A.","family":"Benders","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. J. B. Veldhuis","family":"Kroeze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. H.","family":"Van Der Kolk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,1,5]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"214","volume-title":"Proceedings of the 40th British Equine Veterinary Association Congress","author":"Benders N.A.","year":"2001"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1992.tb02858.x"},{"key":"e_1_2_1_4_1","first-page":"151","article-title":"Esophageal dysfunction in a weanling thoroughbred","volume":"77","author":"Clark E.S.","year":"1987","journal-title":"Cornell Vet."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197604000-00013"},{"key":"e_1_2_1_6_1","first-page":"207","article-title":"Esophageal obstruction in horses: a retrospective study of 34 cases","volume":"41","author":"Feige K.","year":"2000","journal-title":"Can. vet. 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