{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T21:33:47Z","timestamp":1790026427319,"version":"4.0.1"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2010,1,5]],"date-time":"2010-01-05T00:00:00Z","timestamp":1262649600000},"content-version":"vor","delay-in-days":2014,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2004,7]]},"abstract":"Summary<\/jats:title>\n \n Reasons for performing study<\/jats:italic>\n : There is a lack of long\u2010term follow\u2010up data for outcome of medical treatment of superficial digital flexor (SDF) tendonitis.\n <\/jats:p>\n \n Objectives<\/jats:italic>\n : To determine whether intralesional injection of hyaluronan, beta aminoproprionitrile fumarate (BAPN) or polysulphated glycosaminoglycans (PSGAG) or systemic administration of PSGAG yielded better results than a controlled exercise programme alone in the management of SDF tendonitis, with a minimum follow\u2010up period of 2 years after resumption of full work; and to determine whether reinjury rate was related to sports discipline and whether fibre alignment score (FAS) at 4 months could predict outcome.\n <\/jats:p>\n \n Methods<\/jats:italic>\n : In Study 1, 50 horses were managed by controlled exercise alone (\n Group A<\/jats:italic>\n ), 50 were treated with intralesional injection of hyaluronan (\n Group B<\/jats:italic>\n ), 20 received intralesional and systemic treatment with PSGAG (\n Group Ci<\/jats:italic>\n ) and 30 received systemic treatment with PSGAG (\n Group Cii<\/jats:italic>\n ). Horses in\n Groups B, Ci<\/jats:italic>\n and\n Cii<\/jats:italic>\n followed the same controlled exercise programme as\n Group A.<\/jats:italic>\n In\n Study 2<\/jats:italic>\n , 69 horses (\n Group D<\/jats:italic>\n ) were treated by intralesional injection of BAPN and followed a modified controlled exercise programme. Horses were re\u2010examined clinically and ultrasonographically at intervals. Follow\u2010up data were obtained for horses 2 years after resuming full work and for up to 6 years.\n <\/jats:p>\n \n Results<\/jats:italic>\n : There was no significant difference in reinjury rate of the treated limb(s) between\n Groups A, B, Ci<\/jats:italic>\n and\n Cii<\/jats:italic>\n (42.5\u201044.4%) (P>0.9). The reinjury rate (16%) in the treated limb(s) in\n Group D<\/jats:italic>\n was significantly lower than in the other groups (P<0.001). However, when injury rate of the uninjured limb was considered, the results were similar to\n Study 1.<\/jats:italic>\n In\n Study 2<\/jats:italic>\n , the FAS at 4 months after treatment was a good predictor of outcome (P<0.001). Reinjury rates for different disciplines were similar in the 2 studies, with the risk of reinjury ascending from showjumpers to event horses to National Hunt and flat racehorses.\n <\/jats:p>\n \n Conclusions<\/jats:italic>\n : Treatment with BAPN reduced the risk of reinjury in the treated limb, although the overall rate of subsequent injury was not affected. FAS at 4 months after treatment is a good predictor of outcome in the treated limb(s).\n <\/jats:p>\n \n Potential relevance<\/jats:italic>\n : This study provides long\u2010term follow\u2010up data in horses from a variety of sports disciplines that can be used to provide prognostic information.\n <\/jats:p>","DOI":"10.2746\/0425164044868422","type":"journal-article","created":{"date-parts":[[2007,4,12]],"date-time":"2007-04-12T19:03:27Z","timestamp":1176404607000},"page":"415-419","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":182,"title":["Medical management of superficial digital flexor tendonitis: a comparative study in 219 horses (1992\u20102000)"],"prefix":"10.1111","volume":"36","author":[{"given":"S. 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