{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T11:20:57Z","timestamp":1792668057123,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2010,1,5]],"date-time":"2010-01-05T00:00:00Z","timestamp":1262649600000},"content-version":"vor","delay-in-days":919,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Reasons for performing study<\/jats:italic>\n                    : Use of physiological methods of diagnostic imaging could provide insight into the pathogenesis of foot pain in live horses.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Objectives<\/jats:italic>\n                    : To describe patterns and intensity of increased radiopharmaceutical uptake (IRU) in the navicular bone, and relate this to distribution and types of signal intensity change in the navicular bone and to the presence or absence of lesions of the related soft tissue structures detected using MRI.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Materials and methods<\/jats:italic>\n                    : Scintigraphic and MR images of 264 horses with unilateral or bilateral foot pain were analysed and graded. A Spearman rank correlation was used to test for relationships between scintigraphic grade of the navicular bone and MRI scores for each region of the bone. Chi\u2010square tests were used to test for associations between scintigraphy grade and presence of increased signal intensities, for differences in the proportion of focal and diffuse IRU between MRI grades, and for associations between an abnormal scintigraphic grade of the navicular bone and presence or absence of a lesion.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    : There were significant positive correlations between scintigraphy grade and both maximum and total MRI grades for the navicular bone and between scintigraphy grade and the MRI grades for the flexor border, the distal border and medulla. However, there was no difference in the proportions of focal and diffuse IRU between navicular bone MRI grades, although diffuse IRU was relatively under\u2010represented in\n                    <jats:italic>Grade 3<\/jats:italic>\n                    navicular bones. There was no association between IRU in the navicular bone and MR lesions of either the DSIL origin or the CSL insertion, however there was an association between IRU in the navicular bone and combined lesions of the CSL, DSIL and navicular bursa. In limbs with a DDFT lesion, navicular bone scintigraphic\n                    <jats:italic>Grades 2<\/jats:italic>\n                    and\n                    <jats:italic>3<\/jats:italic>\n                    were over\u2010represented.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusions and clinical relevance<\/jats:italic>\n                    : Scintigraphy and MRI provide complementary information about the pathogenesis of lesions of the podotrochlear apparatus. Further understanding of these disease processes may eventually permit more targeted treatments.\n                  <\/jats:p>","DOI":"10.2746\/042516407x185494","type":"journal-article","created":{"date-parts":[[2007,6,28]],"date-time":"2007-06-28T01:39:23Z","timestamp":1182994763000},"page":"365-369","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Use of concurrent scintigraphic and magnetic resonance imaging evaluation to improve understanding of the pathogenesis of injury of the podotrochlear apparatus"],"prefix":"10.1111","volume":"39","author":[{"given":"S.","family":"DYSON","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"MURRAY","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,1,5]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"445","article-title":"Osteoarthritis of the knee: correlation of subchondral magnetic resonance signal abnormalities with histopathologic and radiographic features","volume":"23","author":"Bergman A.","year":"1994","journal-title":"Skeletal Radiol."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516406775374298"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516406775374342"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470690390.ch2"},{"key":"e_1_2_1_6_1","first-page":"107","volume-title":"Proceedings of the 6th Geneva Congress on Equine Medicine and Surgery","author":"Denoix J.M.","year":"1999"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776767231"},{"key":"e_1_2_1_8_1","first-page":"248","article-title":"Collateral desmitis of the distal interphalangeal joint in 62 horses (January 2001 \u2010 December 2003)","volume":"50","author":"Dyson S.","year":"2004","journal-title":"Proc. Am. Ass. equine Practnrs."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516407X185430"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164054223804"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2006.tb00414.x"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516403775467531"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.2746\/042516403775696294"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164044868693"},{"key":"e_1_2_1_15_1","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2460\/ajvr.1996.57.04.415","article-title":"Scintigraphic evaluation of 99mTc\u2010methylene diphosphonate uptake in the navicular area of horses with lameness isolated to the foot by anesthesia of the palmar digital nerves","volume":"57","author":"Keegan K.","year":"1996","journal-title":"Am. J. vet. Res."},{"key":"e_1_2_1_16_1","unstructured":"Lauk H.andWanschura C.(1998)Scintigraphic evaluation of the navicular bone compared to distal toe joint angulation hoof geometry clinical and radiographic findings of navicular disease in 105 horses. In:Proceedings of the 5th Annual Conference of the European Association of Veterinary Diagnostic Imaging."},{"key":"e_1_2_1_17_1","first-page":"210","article-title":"Magnetic resonance imaging of the distal limb of the standing horse: technique and review of 40 cases of foot lameness","volume":"49","author":"Mair T.","year":"2003","journal-title":"Proc. Am. Ass. equine Practnrs."},{"key":"e_1_2_1_18_1","first-page":"359","article-title":"Relationship between nuclear scintigraphy and standing MRI in 30 horses with lameness of the foot","volume":"51","author":"Martinelli M.","year":"2005","journal-title":"Proc. Am. Ass. equine Practnrs."},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2005.00101.x"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2005.00100.x"},{"key":"e_1_2_1_21_1","first-page":"210","article-title":"What magnetic resonance imaging is teaching us about navicular disease","volume":"49","author":"Schneider R.","year":"2003","journal-title":"Proc. Am. Ass. equine Practnrs."},{"key":"e_1_2_1_22_1","first-page":"21","article-title":"Magnetic resonance imaging evaluation of horses with lameness problems","volume":"51","author":"Schneider R.","year":"2005","journal-title":"Proc. Am. Ass. equine Practnrs."},{"key":"e_1_2_1_23_1","first-page":"2011","article-title":"Correlations between uptake of technetium, calcium, phosphate and mineralisation in rat tibial bone repair","volume":"31","author":"Shani J.","year":"1990","journal-title":"J. nucl. Med."},{"key":"e_1_2_1_24_1","first-page":"194","article-title":"Uptake and biodistribution of technetium\u201099m\u2010MD32P during rat tibial bone repair","volume":"34","author":"Schwartz Z.","year":"1993","journal-title":"J. nucl. Med."},{"key":"e_1_2_1_25_1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2460\/javma.1991.198.01.73","article-title":"Soft tissue\u2010 and bone\u2010 phase scintigraphy for diagnosis of navicular disease in horses","volume":"198","author":"Trout D.","year":"1991","journal-title":"J. Am. vet. med. Ass."},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-0233(05)80014-0"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2000.tb01463.x"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.215.3.r00jn05835"}],"container-title":["Equine Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.2746%2F042516407X185494","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/pdf\/10.2746\/042516407X185494","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:09:58Z","timestamp":1762078198000},"score":1,"resource":{"primary":{"URL":"https:\/\/beva.onlinelibrary.wiley.com\/doi\/10.2746\/042516407X185494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.2746\/042516407X185494"],"URL":"https:\/\/doi.org\/10.2746\/042516407x185494","archive":["Portico"],"relation":{},"ISSN":["0425-1644","2042-3306"],"issn-type":[{"value":"0425-1644","type":"print"},{"value":"2042-3306","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7]]},"assertion":[{"value":"2010-01-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}