{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T16:04:44Z","timestamp":1772640284421,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2010,3,19]],"date-time":"2010-03-19T00:00:00Z","timestamp":1268956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["beva.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Equine Veterinary Journal"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Reasons for performing study:<\/jats:bold>\n                    The influence of synovial fluid culture on short\u2010 and long\u2010term prognosis of cases with septic synovitis requires study.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Hypotheses:<\/jats:bold>\n                    Horses with a positive bacterial culture from septic synovial fluid are less likely to survive or return to successful athletic function than those with a negative bacterial culture from septic synovial fluid.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods:<\/jats:bold>\n                    Records of mature horses presented to 2 equine referral hospitals for investigation of suspected septic synovitis were examined. Horses (n = 206) were included in the study if synovial fluid was submitted for full laboratory examination, including bacterial culture. A diagnosis of septic synovitis was based on a nucleated cell count &gt;30 \u00d7 10\n                    <jats:sup>9<\/jats:sup>\n                    cells\/l or &gt;90% neutrophils and other clinical, cytological and bacteriological parameters. Long\u2010term follow\u2010up was obtained by telephone questionnaire. Univariate analysis, using the Fisher's exact test, was used for all outcomes.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Fourteen (20.9%) of 67 horses with a positive bacterial culture from synovial fluid were subjected to euthanasia because of persistent synovial sepsis compared to 2 (1.44%) of 139 with negative bacterial cultures (P&lt;0.001). Overall survival and successful long\u2010term return to function in horses with a positive bacterial culture was 50% (24\/48 horses) compared to 70.5% (74\/105) in culture negative horses (P = 0.01). In horses that survived to be discharged, successful long\u2010term return to function was not significantly different between culture positive and culture negative groups. Growth of\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    from synovial fluid did not affect short\u2010term survival to discharge from the hospital compared to other positive bacterial culture; however, successful long\u2010term return to function was only 30.4% (4\/13) in horses from which\n                    <jats:italic>S. aureus<\/jats:italic>\n                    was cultured compared to 73.9% (17\/23) of horses in which other bacteria were cultured (P = 0.015).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions and potential clinical relevance:<\/jats:bold>\n                    Horses with a positive bacterial culture from a septic synovitis have a poorer prognosis for survival to discharge from hospital and overall long\u2010term return to function than horses that yielded no bacterial growth. When\n                    <jats:italic>S. aureus<\/jats:italic>\n                    was cultured, the long\u2010term prognosis was poorer.\n                  <\/jats:p>","DOI":"10.2746\/042516409x480403","type":"journal-article","created":{"date-parts":[[2010,10,18]],"date-time":"2010-10-18T13:41:54Z","timestamp":1287409314000},"page":"213-218","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Bacterial culture of septic synovial structures of horses: Does a positive bacterial culture influence prognosis?"],"prefix":"10.2746","volume":"42","author":[{"given":"A. H.","family":"TAYLOR","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. S.","family":"MAIR","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. 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