{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:45:19Z","timestamp":1785451519711,"version":"3.56.0"},"reference-count":18,"publisher":"Diving and Hyperbaric Medicine Journal","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diving Hyperb Med"],"abstract":"<jats:p>Introduction: This study aimed to investigate whether hyperbaric oxygen treatment (HBOT) could ameliorate ischaemia-reperfusion injury in a rat model of ovarian torsion-detorsion. Methods: Twenty-seven rats were divided among four groups: surgical sham rats (S) (n = 6) underwent identical anaesthesia and surgical incisions to other groups (n = 7 per group) but with no ovary intervention; torsion rats (T) underwent laparotomy, ovarian torsion, relaparotomy and sacrifice after three hours; torsion and detorsion rats (T\/DT) underwent laparotomy, ovarian torsion (three hours), relaparotomy and detorsion, and sacrifice after one week; torsion, detorsion, hyperbaric oxygen rats (T\/DT\/HBOT) underwent laparotomy, ovarian torsion, relaparotomy and detorsion, and sacrifice after one week during which HBOT was provided 21 times (100% oxygen at 600 kPa for 50 min). In all groups blood collection for markers of oxidative stress or related responses, and ovary collection for histology were performed after sacrifice. Results: When the T\/DT, and T\/DT\/HBOT groups were compared, 8-hydroxy-2\u2032-deoxyguanosine (a marker of oxidative damage to DNA) and malondialdehyde (a product of lipid peroxidation) levels were lower in the T\/DT\/HBOT group.  Anti-Mullerian hormone levels were higher in the T\/DT\/HBOT group compared to the T\/DT group. In addition, oedema, vascular occlusion, neutrophilic infiltration and follicular cell damage were less in the T\/DT\/HBOT group  than in the T\/DT group. Conclusions: When biochemical and histopathological findings were evaluated together, HBOT appeared reduce ovarian ischaemia \/ reperfusion injury in this rat model of ovarian torsion-detorsion.<\/jats:p>","DOI":"10.28920\/dhm54.1.16-22","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T02:17:02Z","timestamp":1710987422000},"page":"16-22","source":"Crossref","is-referenced-by-count":4,"title":["Effect of hyperbaric oxygen treatment on ischaemia-reperfusion injury in rats detorsioned after experimental ovarian torsion"],"prefix":"10.28920","volume":"54","author":[{"name":"Zeynep Kamil Gynecology and Obstetrics Training and Research Hospital, \u0130stanbul, Turkey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2246-4899","authenticated-orcid":false,"given":"Eralp","family":"Bulutlar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Kartal L\u00fctf\u00fc K\u0131rdar Training and Research Hospital \u0130stanbul, Turkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gizem Berfin","family":"Uluutku Bulutlar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Haydarpa\u015fa Numune Training and Research Hospital, \u0130stanbul, Turkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yavuz","family":"Aslan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Sultan Abdulhamid Han Research and Training Hospital","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hale Nur","family":"Bozda\u011f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"VM Medical Park Maltepe Hastanesi, \u0130stanbul , Turkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zafer","family":"K\u00fc\u00e7\u00fckodaci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Anadolu Sa\u011fl\u0131k Merkezi, Gebze, Kocaeli, Turkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"11463","published-online":{"date-parts":[[2024,3,31]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1.McWilliams GDE, Hill MJ, Dietrich CS 3rd. 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