{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:08:15Z","timestamp":1760659695212,"version":"build-2065373602"},"reference-count":0,"publisher":"Diving and Hyperbaric Medicine Journal","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diving Hyperb Med"],"abstract":"<jats:p>Technical and scientific divers breathing gases delivering hyperbaric pressures of inspired oxygen may be at risk of developing cerebral oxygen toxicity which can manifest as a seizure with little or no warning. The principle preventative strategy is adherence to time limits based on inspired PO2 levels promulgated in 1991. These limits had their origins in US Navy studies of exposures to higher inspired PO2s than are typically utilised by modern divers. Indeed, the duration limits for inspired PO2s in the range typically utilised by technical divers (&amp;#x02264; 1.3\u20131.4 atm) have relatively little experimental provenance. Contemporary technical dives often involve decompression durations that result in breaches of these limits, and anecdotally, this common occurrence seems associated with a low risk of cerebral oxygen toxicity. A committee of experts recently sought experimental evidence that might support an adjustment to the recommended duration limits for typical technical dives. Such evidence exists only for an inspired PO2 of 1.3 atm, which is a common default in use of constant PO2 rebreather devices. The (1991) limit for a single exposure to an inspire PO2 of 1.3 atm is 180 min with a 24-hour maximum of 210 min. Recent studies provide reassurance that dives with an inspired PO2 of 1.3 atm consisting of up to 240 min of working dive activity followed by up to 240 min of resting decompression are associated with an acceptably low risk of cerebral oxygen toxicity. This recommendation was promulgated and endorsed at a recent workshop convened by the National Oceanographic and Atmospheric Administration (NOAA) involving technical and scientific divers.<\/jats:p>","DOI":"10.28920\/dhm55.3.262-270","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T02:18:32Z","timestamp":1760581112000},"page":"262-270","source":"Crossref","is-referenced-by-count":0,"title":["Revised guideline for central nervous system oxygen toxicity exposure limits when using an inspired PO2 of 1.3 atmospheres"],"prefix":"10.28920","volume":"55","author":[{"name":"NOAA Diving Program, National Oceanographic and Atmospheric Administration, Seattle, WA, USA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Hoyt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F Gregory","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Navy Experimental Diving Unit, Panama City, FL, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal W","family":"Pollock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Kinesiology, Faculty of Medicine, Universit\u00e9 Laval, Qu\u00e9bec, Canada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Service de m\u00e9decine hyperbare, Centre de m\u00e9decine de plong\u00e9e du Qu\u00e9bec, Levis, Qu\u00e9bec, Canada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn","family":"Kernagis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"DEEP Research Inc., Miami, FL, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Bird","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Hyperbaric Medicine, Virginia Mason Medical Center, Seattle, WA, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Menduno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"InDEPTH Magazine, High Springs, FL, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Bright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"CPC Inc., San Diego, CA, USA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon J","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Anaesthesiology, University of Auckland, Auckland, New Zealand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Anaesthesia, Auckland City Hospital, Auckland, New Zealand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Slark Hyperbaric Unit, North Shore Hospital, Auckland, New Zealand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11463","published-online":{"date-parts":[[2025,9,30]]},"container-title":["Diving and Hyperbaric Medicine Journal"],"original-title":[],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T02:18:45Z","timestamp":1760581125000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.dhmjournal.com\/index.php\/journals?view=article&id=367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,9,30]]}},"URL":"https:\/\/doi.org\/10.28920\/dhm55.3.262-270","relation":{},"ISSN":["2209-1491"],"issn-type":[{"value":"2209-1491","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,30]]}}}