{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T02:23:45Z","timestamp":1775096625266,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EFS2","EFSA Journal"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.2903\/j.efsa.2019.5788","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T12:34:22Z","timestamp":1563798862000},"source":"Crossref","is-referenced-by-count":6,"title":["Safety and efficacy of sodium selenate as feed additive for ruminants"],"prefix":"10.2903","volume":"17","author":[{"name":"EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed (FEEDAP)","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasileios","family":"Bampidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Azimonti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria de Lourdes","family":"Bastos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Dusemund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryline","family":"Kouba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojca","family":"Kos Durjava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"L\u00f3pez\u2010Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Secundino","family":"L\u00f3pez Puente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Marcon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baltasar","family":"Mayo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alena","family":"Pechov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Petkova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolanda","family":"Sanz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto Edoardo","family":"Villa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruud","family":"Woutersen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Cubadda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Flachowsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Mantovani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"L\u00f3pez\u2010G\u00e1lvez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"10.2903\/j.efsa.2019.5788_ref1","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.smallrumres.2009.12.042","article-title":"The importance of selenium and the effects of its deficiency in animal health","volume":"89","author":"Abd El Ghany","year":"2010","journal-title":"Small Ruminant Research"},{"key":"10.2903\/j.efsa.2019.5788_ref2","volume-title":"2012 Guide to Occupational Exposure Values","author":"ACGIH","year":"2012"},{"key":"10.2903\/j.efsa.2019.5788_ref3","unstructured":"Codex Alimentarius , 2008. Advisory lists of nutrient compounds for use in foods for special dietary uses intended for infants and young children. Available online: www.fao.org\/input\/download\/standards\/300\/CXG_010e_2015.pdf"},{"key":"10.2903\/j.efsa.2019.5788_ref4","volume-title":"List of MAK and BAT Values","author":"DFG","year":"2015"},{"key":"10.2903\/j.efsa.2019.5788_ref5","volume-title":"Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Selenium","author":"EC","year":"2000"},{"key":"10.2903\/j.efsa.2019.5788_ref6","unstructured":"EC (European Commission), 2011. Recommendation from the Scientific Committee on Occupational Exposure Limits (SCOEL) for nickel and inorganic nickel compounds. Employment, Social Affairs and Inclusion. SCOEL\/SUM\/85, June 2011."},{"key":"10.2903\/j.efsa.2019.5788_ref7","doi-asserted-by":"crossref","unstructured":"EFSA (European Food Safety Authority), 2008. Technical Guidance of the Scientific Panel\u00a0on Additives and Products or Substances used in Animal Feed (FEEDAP) for assessing the safety of feed additives for the environment. EFSA Journal 2008;6(10):842, 28\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2008.842","DOI":"10.2903\/j.efsa.2008.842"},{"key":"10.2903\/j.efsa.2019.5788_ref8","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2011a. Technical guidance: Tolerance and efficacy studies in target animals. EFSA Journal 2011;9(5):2175, 15\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2011.2175","DOI":"10.2903\/j.efsa.2011.2175"},{"key":"#cr-split#-10.2903\/j.efsa.2019.5788_ref9.1","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2011b. EFSA Journal 2011;9(4):2110 Suggested citation: EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed (FEEDAP)"},{"key":"#cr-split#-10.2903\/j.efsa.2019.5788_ref9.2","doi-asserted-by":"crossref","unstructured":"Scientific Opinion on Safety and efficacy of Sel\u2010Plex\u00ae (organic form of selenium produced by Saccharomyces cerevisiae CNCM I\u20103060) for all species. EFSA Journal 2011;9(4):2110, 52\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2011.2110","DOI":"10.2903\/j.efsa.2011.2110"},{"key":"10.2903\/j.efsa.2019.5788_ref10","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2012a. Guidance for the preparation of dossiers for nutritional additives. EFSA Journal 2012;10(1):2535, 14\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2012.2535","DOI":"10.2903\/j.efsa.2012.2535"},{"key":"10.2903\/j.efsa.2019.5788_ref11","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2012b. Guidance for the preparation of dossiers for additives already authorised for use in food. EFSA Journal 2012;10(1):2538, 4\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2012.2538","DOI":"10.2903\/j.efsa.2012.2538"},{"key":"10.2903\/j.efsa.2019.5788_ref12","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2012c. Guidance for establishing the safety of additives for the consumer. EFSA Journal 2012;10(1):2537, 12\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2012.2537","DOI":"10.2903\/j.efsa.2012.2537"},{"key":"10.2903\/j.efsa.2019.5788_ref13","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2012d. Guidance on studies concerning the safety of use of the additive for users\/workers. EFSA Journal 2012;10(1):2539, 5\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2012.2539","DOI":"10.2903\/j.efsa.2012.2539"},{"key":"10.2903\/j.efsa.2019.5788_ref14","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2015. Scientific Opinion on the safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite (coated granulated preparation), based on a dossier submitted by Doxal Italia S.p.A. EFSA Journal 2015;13(11):4271, 27\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2015.4271","DOI":"10.2903\/j.efsa.2015.4271"},{"key":"10.2903\/j.efsa.2019.5788_ref15","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2016a. Scientific opinion on the safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite based on a dossier submitted by Retorte GmbH Selenium Chemicals and Metals. EFSA Journal 2016;14(2):4398, 26\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2016.4398","DOI":"10.2903\/j.efsa.2016.4398"},{"key":"10.2903\/j.efsa.2019.5788_ref16","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel\u00a0on Additives and Products or Substances used in Animal Feed), 2016b. Scientific opinion on the safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite, based on a dossier submitted by Todini and Co SpA. EFSA Journal 2016;14(3):4442, 24\u00a0pp. https:\/\/doi.org\/10.2903\/j.efsa.2016.4442","DOI":"10.2903\/j.efsa.2016.4442"},{"key":"10.2903\/j.efsa.2019.5788_ref17","doi-asserted-by":"crossref","unstructured":"EFSA Feedap Panel (EFSA Panel on additives and products or substances usedin animal feed), Rychen G, Aquilina G, Azimonti G, Bampidis V, Bastos ML, Bories G, Chesson A, Cocconcelli PS, Flachowsky G, Gropp J, Kolar B, Kouba M, Lopez\u2010Alonso M, Lopez Puente S, Mantovani A, Mayo B, Ramos F, Saarela M, Villa RE, Wallace RJ, Wester P, Anguita M, Galobart J, Innocenti ML and Martino L, 2017. Guidance on the assessment of the safety of feed additives for the target species. EFSA Journal 2017;15(10):5021, 19 pp. https:\/\/doi.org\/10.2903\/j.efsa.2017.5021","DOI":"10.2903\/j.efsa.2017.5021"},{"key":"10.2903\/j.efsa.2019.5788_ref18","unstructured":"EMA (European Medicines Agency), 2015. European public MRL assessment report (EPMAR) \u2013 potassium selenate (all food producing species), sodium selenate (all food producing species), sodium selenite (all food producing species). Committee for Veterinary Medicinal Products. Available online: http:\/\/www.ema.europa.eu\/ema\/pages\/includes\/document\/open_document.jsp?webContentId=WC500185181"},{"key":"10.2903\/j.efsa.2019.5788_ref19","first-page":"19","article-title":"Mineral Nutrition of Grazing Goats in Luzon Island, Philippines","volume":"11","author":"Fujihara","year":"2006","journal-title":"Bulletin of the Faculty of Life and Environmental Science, Shimane University"},{"key":"10.2903\/j.efsa.2019.5788_ref20","doi-asserted-by":"crossref","first-page":"3934","DOI":"10.2527\/1992.70123934x","article-title":"Effect of selenium supplementation on dairy cattle","volume":"70","author":"Gerloff","year":"1992","journal-title":"Journal of Animal Science"},{"key":"10.2903\/j.efsa.2019.5788_ref21","unstructured":"Grace ND, Knowles SO and Sykes AR, 2010. Managing Mineral Deficiencies in Grazing Livestock. Edition: Occasional Publication No. 15 Publisher: New Zealand Society of Animal."},{"key":"10.2903\/j.efsa.2019.5788_ref22","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1740-0929.2006.00391.x","article-title":"Effect of soluble glass bolus administration on the blood selenium concentration in grazing Philippine goats under backyard conditions","volume":"77","author":"Hayashida","year":"2006","journal-title":"Animal Science Journal"},{"key":"10.2903\/j.efsa.2019.5788_ref23","volume-title":"Bioavailability of Major and Trace Minerals","author":"Jongbloed","year":"2002"},{"key":"10.2903\/j.efsa.2019.5788_ref24","doi-asserted-by":"crossref","DOI":"10.1201\/b10158","volume-title":"Trace elements in soils and plants","author":"Kabata\u2010Pendias","year":"2010"},{"key":"10.2903\/j.efsa.2019.5788_ref25","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1080\/00480169.1988.35463","article-title":"Selenium levels in the blood, liver, kidney and muscle of sheep after the administration of iron\/ selenium pellets or soluble\u2010glass boluses","volume":"36","author":"Millar","year":"1988","journal-title":"New Zealand Veterinary Journal"},{"key":"10.2903\/j.efsa.2019.5788_ref26","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0960-8524(99)00017-6","article-title":"Heavy metal contents of livestock feeds and animal manures in England and Wales","volume":"70","author":"Nicholson","year":"1999","journal-title":"Bioresource Technology"},{"key":"10.2903\/j.efsa.2019.5788_ref27","volume-title":"Predicting Feed Intake of Food\u2010producing Animals","author":"NRC","year":"1987"},{"key":"10.2903\/j.efsa.2019.5788_ref28","volume-title":"Mineral Tolerance of Animals","author":"NRC","year":"2005"},{"key":"10.2903\/j.efsa.2019.5788_ref29","unstructured":"NTP (National Toxicology Program), 1994. NTP Technical Report on Toxicity Studies of Sodium Selenate and Sodium Selenite. Available online: https:\/\/ntp.niehs.nih.gov\/ntp\/htdocs\/st_rpts\/tox038.pdf"},{"key":"10.2903\/j.efsa.2019.5788_ref30","unstructured":"OSHA (Occupational Safety and Health Administration), 2018. Tellurium and metal compounds. Available online: https:\/\/www.osha.gov\/chemicaldata\/chemResult.html?RecNo=248"},{"key":"10.2903\/j.efsa.2019.5788_ref31","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF02784182","article-title":"Effect of Selenium in Soluble Glass Bolus on Selenium Content of Milk and Blood of Goats","volume":"55","author":"Serra","year":"1996","journal-title":"Biological Trace Element Research"},{"key":"10.2903\/j.efsa.2019.5788_ref32","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.2527\/2006.8461439x","article-title":"Effects of a long\u2010acting, trace mineral, reticulorumen bolus on range cow productivity and trace mineral profiles","author":"Sprinkle","year":"2006","journal-title":"Journal of Animal Science"},{"key":"10.2903\/j.efsa.2019.5788_ref33","doi-asserted-by":"crossref","unstructured":"Underwood EJ and Suttle NF, 1999. The Mineral Nutrition of Livestock, 3rd edition. CABI Publishing, Wallingford, Oxon.","DOI":"10.1079\/9780851991283.0000"},{"key":"10.2903\/j.efsa.2019.5788_ref34","doi-asserted-by":"crossref","unstructured":"Van Paemel M, Dierick N, Janssens G, Fievez V and De Smet S, 2010. Selected trace and ultratrace elements: Biological role, content in feed and requirements in animal nutrition\u2014Elements for risk assessment. Technical Report submitted to EFSA. Available online: http:\/\/www.efsa.europa.eu\/en\/supporting\/pub\/68e.htm","DOI":"10.2903\/sp.efsa.2010.EN-68"}],"container-title":["EFSA Journal"],"original-title":[],"link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.2903\/j.efsa.2019.5788","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.2903\/j.efsa.2019.5788\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T19:52:50Z","timestamp":1628193170000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.2903\/j.efsa.2019.5788"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":35,"journal-issue":{"issue":"7"},"URL":"https:\/\/doi.org\/10.2903\/j.efsa.2019.5788","relation":{},"ISSN":["1831-4732","1831-4732"],"issn-type":[{"value":"1831-4732","type":"print"},{"value":"1831-4732","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}