{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T09:58:46Z","timestamp":1723024726812},"reference-count":35,"publisher":"Wiley","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EFS2","EFSA Journal"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.2903\/j.efsa.2022.7090","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T04:14:33Z","timestamp":1644812073000},"source":"Crossref","is-referenced-by-count":1,"title":["Scientific Opinion on Flavouring Group Evaluation 7, Revision 6 (FGE.07Rev6): saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched\u2010chain carboxylic acids from chemical group 5"],"prefix":"10.2903","volume":"20","author":[{"name":"EFSA Panel on Food Additives and Flavourings (FAF)","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maged","family":"Younes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Aquilina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence","family":"Castle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl\u2010Heinz","family":"Engel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J","family":"Fowler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jose","family":"Frutos Fernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"F\u00fcrst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Gundert\u2010Remy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"G\u00fcrtler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trine","family":"Hus\u00f8y","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melania","family":"Manco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Moldeus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabina","family":"Passamonti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romina","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ine","family":"Waalkens\u2010Berendsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Detlef","family":"W\u00f6lfle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Wright","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romualdo","family":"Benigni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Bolognesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Chipman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugenia","family":"Cordelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisela","family":"Degen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Marzin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin Kristiane","family":"N\u00f8rby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilla","family":"Svendsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgia","family":"Vianello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim","family":"Mennes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"10.2903\/j.efsa.2022.7090_ref1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0015-6264(76)80522-6","article-title":"Estimation of toxic hazard \u2010 a decision tree approach","volume":"16","author":"Cramer","year":"1978","journal-title":"Food and Cosmetics Toxicology"},{"key":"10.2903\/j.efsa.2022.7090_ref2","doi-asserted-by":"crossref","unstructured":"EFSA AFC Panel (EFSA panel on Food Additives, Flavourings, Processing Aids and Materials in Contacts with Food) , 2004. Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 7 (FGE.07): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched\u2010chain carboxylic acids from chemical group 5. EFSA Journal 2004;3(2):164, 63 pp. https:\/\/doi.org\/10.2903\/j.efsa.2005.164","DOI":"10.2903\/j.efsa.2005.164"},{"key":"10.2903\/j.efsa.2022.7090_ref3","doi-asserted-by":"crossref","unstructured":"EFSA AFC Panel (EFSA panel on Food Additives, Flavourings, Processing Aids and Materials in Contacts with Food) , 2008. Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission. EFSA Journal 2008;6(6):722, 64 pp. https:\/\/doi.org\/10.2903\/j.efsa.2008.722","DOI":"10.2903\/j.efsa.2008.601"},{"key":"10.2903\/j.efsa.2022.7090_ref4","doi-asserted-by":"crossref","unstructured":"EFSA CEF Panel (EFSA panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) , 2009. Flavouring Group Evaluation 7, Revision 2 (FGE.07Rev2) 1: Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched\u2010chain carboxylic acids from chemical group 5. EFSA Journal 2009;7(7):1020, 70 pp. https:\/\/doi.org\/10.2903\/j.efsa.2009.1020","DOI":"10.2903\/j.efsa.2009.1020"},{"key":"10.2903\/j.efsa.2022.7090_ref5","doi-asserted-by":"crossref","unstructured":"EFSA CEF Panel (EFSA panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) , 2010. Flavouring Group Evaluation 7, Revision 3 (FGE.07Rev3): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched\u2010chain carboxylic acids from chemical group 5. EFSA Journal 2010;8(12):1845, 45 pp. https:\/\/doi.org\/10.2903\/j.efsa.2010.1845","DOI":"10.2903\/j.efsa.2010.1845"},{"key":"10.2903\/j.efsa.2022.7090_ref6","doi-asserted-by":"crossref","unstructured":"EFSA CEF Panel (EFSA panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) , 2011. Scientific Opinion on Flavouring Group Evaluation 206 (FGE.206): Consideration of genotoxicity data on representatives for 12 alpha,beta\u2010unsaturated ketones and precursors from chemical subgroup 1.2.3 of FGE.19 by EFSA. EFSA Journal 2011;9(3):1922, 45 pp. https:\/\/doi.org\/10.2903\/j.efsa.2011.1922","DOI":"10.2903\/j.efsa.2011.1922"},{"key":"10.2903\/j.efsa.2022.7090_ref7","doi-asserted-by":"crossref","unstructured":"EFSA CEF Panel (EFSA panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) , 2012. Scientific Opinion on Flavouring Group Evaluation 7, Revision 4 (FGE.07Rev4): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched\u2010chain carboxylic acids from chemical group 5. EFSA Journal 2012;10(10):2899, 78 pp. https:\/\/doi.org\/10.2903\/j.efsa.2012.2899","DOI":"10.2903\/j.efsa.2012.2899"},{"key":"10.2903\/j.efsa.2022.7090_ref8","doi-asserted-by":"crossref","unstructured":"EFSA CEF Panel (EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) , 2016. Scientific opinion of Flavouring Group Evaluation 205 Revision 1 (FGE.205Rev1): consideration of genotoxicity data on representatives for 13 \u03b1,\u03b2\u2010unsaturated aliphatic ketones with terminal double bonds and precursors from chemical subgroup 1.2.2 of FGE.19. EFSA Journal 2016;14(7):4535, 69 pp. https:\/\/doi.org\/10.2903\/j.efsa.2016.4535","DOI":"10.2903\/j.efsa.2016.4535"},{"key":"10.2903\/j.efsa.2022.7090_ref9","doi-asserted-by":"crossref","unstructured":"EFSA CEF Panel (EFSA panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) , 2017a. Scientific Opinion on Flavouring Group Evaluation 7, Revision 5 (FGE.07Rev5): saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched\u2010chain carboxylic acids from chemical group 5. EFSA Journal 2017;15(3):4725, 89 pp. https:\/\/doi.org\/10.2903\/j.efsa.2017.4725","DOI":"10.2903\/j.efsa.2017.4725"},{"key":"10.2903\/j.efsa.2022.7090_ref10","doi-asserted-by":"crossref","unstructured":"EFSA CEF Panel (EFSA panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) , 2017b. Scientific Opinion on Flavouring Group Evaluation 63, Revision 3 (FGE.63Rev3): aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th and 69th meetings) structurally related to saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched\u2010chain carboxylic acids evaluated by EFSA in FGE.07Rev4. EFSA Journal 2017;15(1):4662, 78 pp. https:\/\/doi.org\/10.2903\/j.efsa.2017.4662","DOI":"10.2903\/j.efsa.2017.4662"},{"key":"10.2903\/j.efsa.2022.7090_ref11","doi-asserted-by":"crossref","unstructured":"EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings) , 2018a. Scientific Opinion on Flavouring Group Evaluation 201 Revision 2 (FGE.201Rev2): 2\u2010alkylated, aliphatic, acyclic alpha,beta\u2010unsaturated aldehydes and precursors, with or without additional double\u2010bonds, from chemical subgroup 1.1.2 of FGE.19. EFSA Journal 2018;16(10):5423, 45 pp. https:\/\/doi.org\/10.2903\/j.efsa.2018.5423","DOI":"10.2903\/j.efsa.2018.5423"},{"key":"10.2903\/j.efsa.2022.7090_ref12","doi-asserted-by":"crossref","unstructured":"EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings) , 2018b. Scientific Opinion on Flavouring Group Evaluation 200. Revision 1 (FGE.200 Rev.1): 74 \u03b1,\u03b2\u2010unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.1 of FGE.19. EFSA Journal 2018;16(10):5422, 60 pp. https:\/\/doi.org\/10.2903\/j.efsa.2018.5422","DOI":"10.2903\/j.efsa.2018.5422"},{"key":"10.2903\/j.efsa.2022.7090_ref13","doi-asserted-by":"crossref","unstructured":"EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings) , 2019. Scientific Opinion on Flavouring Group Evaluation 204 Revision 1 (FGE.204Rev1): consideration of genotoxicity data on representatives for 17 monounsaturated, aliphatic, \u03b1,\u03b2\u2010unsaturated ketones and precursors from chemical subgroup 1.2.1 of FGE.19. EFSA Journal 2019;17(7):5750, 45 pp. https:\/\/doi.org\/10.2903\/j.efsa.2019.5750","DOI":"10.2903\/j.efsa.2019.5750"},{"key":"10.2903\/j.efsa.2022.7090_ref14","doi-asserted-by":"crossref","unstructured":"EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings) , 2022. Scientific Opinion on Flavouring Group Evaluation 63, revision 4 (FGE.63Rev4): consideration of aliphatic secondary alcohols, ketones and related esters evaluated by JECFA (59th and 69th meetings) structurally related to flavourings substances evaluated by EFSA in FGE.07Rev6. EFSA Journal 2022;20(2):7102, 46 pp. https:\/\/doi.org\/10.2903\/j.efsa.2022.7102","DOI":"10.2903\/j.efsa.2021.7102"},{"key":"10.2903\/j.efsa.2022.7090_ref15","doi-asserted-by":"crossref","unstructured":"EFSA Scientific Committee , 2009. Guidance of the Scientific Committee on Transparency in the Scientific Aspects of Risk Assessments carried out by EFSA. Part 2: general Principles. EFSA Journal 2009;7(7):1051, 22 pp. https:\/\/doi.org\/10.2903\/j.efsa.2009.1051","DOI":"10.2903\/j.efsa.2009.1051"},{"key":"10.2903\/j.efsa.2022.7090_ref16","unstructured":"Eurostat , 1998. Total population. Cited in Eurostat, 2004. The EU population, Total population. Available online: https:\/\/epp.eurostat.ec.europa.eu\/portal\/page?_pageid=1090,30070682,1090_33076576&_dad=portal&_schema=PORTAL, Population and social conditions, Population, Demography, Main demographic indicators, Total population. December 2008."},{"key":"10.2903\/j.efsa.2022.7090_ref17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/03602538008994021","article-title":"Mammalian carbonyl reductases","volume":"11","author":"Felsted","year":"1980","journal-title":"Drug Metabolism Reviews"},{"key":"10.2903\/j.efsa.2022.7090_ref18","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 1995. Evaluation of certain food additives and contaminants. Forty\u2010fourth Meeting of the Joint FAO\/WHO Expert Committee on Food Additives. WHO Technical Report Series, no. 859. Geneva."},{"key":"10.2903\/j.efsa.2022.7090_ref19","unstructured":"JECFA (Joint FAO, WHO Expert Committee on Food Additives) , 1996. Toxicological evaluation of certain food additives. The forty\u2010fourth meeting of the Joint FAO\/WHO Expert Committee on Food Additives and contaminants."},{"key":"10.2903\/j.efsa.2022.7090_ref20","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 1997. Evaluation of certain food additives and contaminants. Forty\u2010sixth report of the Joint FAO\/WHO Expert Committee on Food Additives. Geneva, 6\u201315 February 1996. WHO Technical Report Series, no. 868. Geneva."},{"key":"10.2903\/j.efsa.2022.7090_ref21","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 1998. Compendium of food additive specifications. Addendum 6. Joint FAO\/WHO Expert Committee of Food Additives 51st session. Geneva, 9\u201018 June 1998. FAO Food and Nutrition paper 52 Add. 6.*"},{"key":"10.2903\/j.efsa.2022.7090_ref22","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 1999. Evaluation of certain food additives and contaminants. Forty\u2010ninth report of the Joint FAO\/WHO Expert Committee on Food Additives. Rome, 17\u201326 June 1997. WHO Technical Report Series, no. 884. Geneva."},{"key":"10.2903\/j.efsa.2022.7090_ref23","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 2000. Evaluation of certain food additives. Fifty first Meeting of the Joint FAO\/WHO Expert Committee on Food Additives. Geneva, 9\u201318 June 1998. WHO Technical Report Series, no. 891. Geneva."},{"key":"10.2903\/j.efsa.2022.7090_ref24","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 2002a. Evaluation of certain food additives. Fifty ninth report of the Joint FAO\/WHO Expert Committee on Food Additives. WHO Technical Report Series, no. 913. Geneva, 4\u201313 June 2002."},{"key":"10.2903\/j.efsa.2022.7090_ref25","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 2002b. Evaluation of certain food additives and contaminants. Fifty\u2010seventh report of the Joint FAO\/WHO Expert Committee on Food Additives. WHO Technical Report Series, no. 909. Geneva, 5\u201314 June 2001."},{"key":"10.2903\/j.efsa.2022.7090_ref26","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 2003. Safety evaluation of certain food additives. Fifty\u2010ninth Meeting of the Joint FAO\/WHO Expert Committee on Food Additives, WHO Food Additives Series: 50. IPCS, WHO, Geneva."},{"key":"10.2903\/j.efsa.2022.7090_ref27","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 2006. Evaluation of certain food additives. Sixty\u2010fifth report of the Joint FAO\/WHO Expert Committee on Food Additives. WHO Technical Report Series, no. 934. Geneva, 7\u201016 June 2005."},{"key":"10.2903\/j.efsa.2022.7090_ref28","unstructured":"JECFA (Joint FAO, WHO Expert Committee on Food Additives) , 2007. Evaluation of certain food additives and contaminants. Sixty\u2010eighth report of the Joint FAO\/WHO Expert Committee on Food Additives. WHO Technical Report Series, 947."},{"key":"10.2903\/j.efsa.2022.7090_ref29","unstructured":"JECFA (Joint FAO\/WHO Expert Committee on Food Additives) , 2009. Evaluation of certain food additives. Sixty ninth report of the Joint FAO\/WHO Expert Committee on Food Additives. WHO Technical Report Series, no. 952. Rome, 17\u201026 June 2008. Available online: https:\/\/whqlibdoc.who.int\/trs\/WHO_TRS_952_eng.pdf [Accessed: May 2009]."},{"key":"10.2903\/j.efsa.2022.7090_ref30","unstructured":"Krasavage WJ and O\u2019Donoghue JL, 1979. Repeated oral administration of five ketones and n\u2010heptane to rats. March 1, 1979. Unpublished report submitted by EFFA to SCF."},{"volume-title":"Patty\u2019s Industrial Hygiene and Toxicology","year":"1993","author":"Clayton","key":"10.2903\/j.efsa.2022.7090_ref31"},{"key":"10.2903\/j.efsa.2022.7090_ref32","unstructured":"SCF (Scientific Committee on Food) , 1995. First annual report on chemically defined flavouring substances. May 1995, 2nd draft prepared by the SCF Working Group on Flavouring Substances (Submitted by the SCF Secretariat, 17 May 1995). CS\/FLAV\/FL\/140\u2010Rev2. Annex 6 to Document III\/5611\/95, European Commission, Directorate\u2010General III, Industry."},{"key":"10.2903\/j.efsa.2022.7090_ref33","unstructured":"SCF (Scientific Committee on Food) , 1999. Opinion on a programme for the evaluation of flavouring substances (expressed on 2 December 1999). SCF\/CS\/FLAV\/TASK\/11 Final 6\/12\/1999. Annex I the minutes of the 119th Plenary meeting. European Commission, Health & Consumer Protection Directorate\u2010General."},{"key":"10.2903\/j.efsa.2022.7090_ref34","first-page":"1739","volume-title":"Patty\u2019s Industrial Hygiene and Toxicology","author":"Clayton","year":"1994"},{"key":"10.2903\/j.efsa.2022.7090_ref35","unstructured":"VCF (Volatile Compounds in Food) online database , 2021. Version 16.8, BeWiDo BV 1992\u20132021. Available online: https:\/\/www.vcf\u2010online.nl\/VcfHome.cfm"}],"container-title":["EFSA Journal"],"original-title":[],"link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.2903\/j.efsa.2022.7090","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.2903\/j.efsa.2022.7090\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T02:02:13Z","timestamp":1678759333000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.2903\/j.efsa.2022.7090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":35,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.2903\/j.efsa.2022.7090","relation":{},"ISSN":["1831-4732","1831-4732"],"issn-type":[{"type":"print","value":"1831-4732"},{"type":"electronic","value":"1831-4732"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}