{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T13:40:05Z","timestamp":1744206005059,"version":"3.40.3"},"reference-count":4,"publisher":"Wiley","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EFS2","EFSA Journal"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Abstract\r\n Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety of a feed additive consisting of dicopper chloride trihydroxide intended for use as a nutritional additive (functional group: compounds of trace elements) for all animal species. Regarding the safety for the user, in the previous assessment, the FEEDAP Panel concluded that the additive is hazardous by inhalation, it is irritant to skin and eye and a skin and respiratory sensitiser. For the current assessment, arguments have been provided by the applicant in support of the safety of the additive for the users exposed by inhalation. The FEEDAP Panel concluded that dicopper chloride trihydroxide is irritant to skin, eyes and the respiratory system and should be considered a skin and respiratory sensitiser. Any exposure is considered a risk. \r\n<\/jats:p>","DOI":"10.2903\/j.efsa.2025.9341","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T10:17:36Z","timestamp":1744193856000},"source":"Crossref","is-referenced-by-count":0,"title":["Safety of a feed additive consisting of dicopper chloride trihydroxide for all animal species (Nutreco Nederland B.V.)"],"prefix":"10.2903","volume":"23","author":[{"name":"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto Edoardo","family":"Villa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna","family":"Azimonti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleftherios","family":"Bonos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Christensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojca","family":"Durjava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Dusemund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronette","family":"Gehring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boet","family":"Glandorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryline","family":"Kouba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"L\u00f3pez\u2010Alonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Marcon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Nebbia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alena","family":"Pechov\u00e1","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Prieto\u2010Maradona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilen","family":"R\u00f6he","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerina","family":"Theodoridou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaume","family":"Galobart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiola","family":"Pizzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"10.2903\/j.efsa.2025.9341_ref1","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel on Additives and Products or Substances used in Animal Feed) . (2011). Scientific Opinion on safety and efficacy of dicopper chloride tri hydroxide (tribasic copper chloride, TBCC) as feed additive for all species. EFSA Journal, 9(9), 2355. https:\/\/doi.org\/10.2903\/j.efsa.2011.2355","DOI":"10.2903\/j.efsa.2011.2355"},{"key":"10.2903\/j.efsa.2025.9341_ref2","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel on Additives and Products or Substances used in Animal Feed) , Bampidis, V., Azimonti, G., Bastos, M. L., Christensen, H., Dusemund, B., Durjava, M., Kouba, M., Lopez\u2010Alonso, M., Lopez Puente, S., Marcon, F., Mayo, B., Pechova, A., Petkova, M., Ramos, F., Villa, R. E., Woutersen, R., Bories, G., Gropp, J., \u2026 Radovnikovic, A. (2023a). Assessment of the application for renewal of the authorisation of a feed additive consisting of dicopper chloride trihydroxide for all animal species (Nutreco Nederland B.V.). EFSA Journal, 21(10), 8342. https:\/\/doi.org\/10.2903\/j.efsa.2023.8342","DOI":"10.2903\/j.efsa.2023.8342"},{"key":"10.2903\/j.efsa.2025.9341_ref3","doi-asserted-by":"crossref","unstructured":"EFSA FEEDAP Panel (EFSA Panel on Additives and Products or Substances used in Animal Feed) , Bampidis, V., Azimonti, G., Bastos, M. d. L., Christensen, H., Durjava, M., Dusemund, B., Kouba, M., L\u00f3pez\u2010Alonso, M., L\u00f3pez Puente, S., Marcon, F., Mayo, B., Pechov\u00e1, A., Petkova, M., Ramos, F., Villa, R. E., Woutersen, R., Brantom, P., Bastos, M. L., \u2026 Galobart, J. (2023b). Guidance on the assessment of the safety of feed additives for the users. EFSA Journal, 21(12), 8469. https:\/\/doi.org\/10.2903\/j.efsa.2023.8469","DOI":"10.2903\/j.efsa.2023.8469"},{"key":"10.2903\/j.efsa.2025.9341_ref4","unstructured":"European Commission . (2014). Recommendation from the Scientific Committee on Occupational Exposure Limits (SCOEL) for Copper and its inorganic compounds. 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