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In total, 340 notifications were received between October 2022 and September 2025, of which, 190 were of microorganisms used for the production of feed additives, 87 for the production of food enzymes, food additives and flavourings, 3 for food contact materials, 22 as Plant Protection Products (PPPs) and 38 for novel foods. Bacteriophages, previously ineligible for the QPS status, are now eligible at the species level. The QPS list has been updated in relation to the most recent taxonomic insights and the qualifications were revised and streamlined. A BIOHAZ Panel Statement on how to interpret the QPS qualification on \u2018acquired antimicrobial resistance genes\u2019 was published and revised; the qualification \u2018for production purposes only\u2019 was extended to production strains or biomass; the qualification on genetic modified microorganisms (GMMs) was also extended to production strains, biomass or active agents, when the gene of concern is removed. Since 2023, Chlamydomonas reinhardtii, Microchloropsis gaditana, Candida oleophila, Vibrio natriegens and Agrobacterium radiobacter were recommended for QPS status with the qualification for \u2018production purposes only\u2019. Clostridium tyrobutyricum also but with the qualification \u2018absence of genetic determinants for toxin production\u2019. Lacticaseibacillus huelsenbergensis and Lactobacillus paragasseri (formerly included in Lactobacillus gasseri) were also included. Bacillus sonorensis was also recommended with the qualifications \u2018absence of bacitracin production ability\u2019 and \u2018absence of toxigenic activity\u2019. Bacillus thuringiensis was not recommended for the QPS list due to safety concerns.<\/jats:p>","DOI":"10.2903\/j.efsa.2026.9823","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T09:49:47Z","timestamp":1769075387000},"source":"Crossref","is-referenced-by-count":36,"title":["Update of the list of QPS\u2010recommended biological agents intentionally added to food or feeds as notified to EFSA"],"prefix":"10.2903","volume":"24","author":[{"name":"EFSA Panel on Biological Hazards 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Scientific Opinion on the risks for public health related to the presence of Bacillus cereus and other Bacillus spp. including Bacillus thuringiensis in foodstuffs. EFSA Journal, 14(7), 4524. https:\/\/doi.org\/10.2903\/j.efsa.2016.4524","DOI":"10.2903\/j.efsa.2016.4524"},{"key":"10.2903\/j.efsa.2026.9823_ref21","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Ricci, A., Allende, A., Bolton, D., Chemaly, M., Davies, R., Girones, R., Herman, L., Koutsoumanis, K., Lindqvist, R., N\u00f8rrung, B., Robertson, L., Ru, G., Sanaa, M., Simmons, M., Skandamis, P., Snary, E., Speybroeck, N., Ter Kuile, B., \u2026 Fernandez Escamez, P. S. (2017). Scientific Opinion on the update of the list of QPS\u2010recommended biological agents intentionally added to food or feed as notified to EFSA. EFSA Journal, 5(3), 4664. https:\/\/doi.org\/10.2903\/j.efsa.2017.4664","DOI":"10.2903\/j.efsa.2017.4664"},{"key":"10.2903\/j.efsa.2026.9823_ref22","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Ricci, A., Allende, A., Bolton, D., Chemaly, M., Davies, R., Girones, R., Koutsoumanis, K., Lindqvist, R., N\u00f8rrung, B., Robertson, L., Ru, G., Fern\u00e1ndez Esc\u00e1mez, P. S., Sanaa, M., Simmons, M., Skandamis, P., Snary, E., Speybroeck, N., Ter Kuile, B., \u2026 Herman, L. (2018). Statement on the update of the list of QPS\u2010recommended biological agents intentionally added to food or feed as notified to EFSA 7: Suitability of taxonomic units notified to EFSA until September 2017. EFSA Journal, 5(1), 5131. https:\/\/doi.org\/10.2903\/j.efsa.2018.5131","DOI":"10.2903\/j.efsa.2018.5131"},{"key":"10.2903\/j.efsa.2026.9823_ref23","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Koutsoumanis, K., Allende, A., Alvarez\u2010 Ord\u00f3\u00f1ez, A., Bolton, D., Bover\u2010 Cid, S., Chemaly, M., Davies, R., De Cesare, A., Hilbert, F., Lindqvist, R., Nauta, M., Peixe, L., Ru, G., Simmons, M., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., & Herman, L. (2020a). Scientific Opinion on the update of the list of QPS\u2010 recommended biological agents intentionally added to food or feed as notified to EFSA (2017\u20132019). EFSA Journal, 18(2), 5966. https:\/\/doi.org\/10.2903\/j.efsa.2020.5966","DOI":"10.2903\/j.efsa.2020.5966"},{"key":"10.2903\/j.efsa.2026.9823_ref24","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Koutsoumanis, K., Allende, A., Alvarez\u2010 Ord\u00f3\u00f1ez, A., Bolton, D., Bover\u2010 Cid, S., Chemaly, M., Davies, R., De Cesare, A., Hilbert, F., Lindqvist, R., Nauta, M., Peixe, L., Ru, G., Simmons, M., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., & Herman, L. (2020b). Statement on the update of the list of QPS\u2010 recommended biological agents intentionally added to food or feed as notified to EFSA 12: Suitability of taxonomic units notified to EFSA until march 2020. EFSA Journal, 18(7), 6174. https:\/\/doi.org\/10.2903\/j.efsa.2020.6174","DOI":"10.2903\/j.efsa.2020.6174"},{"key":"10.2903\/j.efsa.2026.9823_ref25","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Koutsoumanis, K., Allende, A., \u00c1lvarez\u2010Ord\u00f3\u00f1ez, A., Bolton, D., Bover\u2010Cid, S., Chemaly, M., De Cesare, A., Hilbert, F., Lindqvist, R., Nauta, M., Nonno, R., Peixe, L., Ru, G., Simmons, M., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Su\u00e1rez, J. E., \u2026 Herman, L. (2023a). Statement on how to interpret the QPS qualification on \u2018acquired antimicrobial resistance genes\u2019. EFSA Journal, 21(10), 8323. https:\/\/doi.org\/10.2903\/j.efsa.2023.8323","DOI":"10.2903\/j.efsa.2023.8323"},{"key":"10.2903\/j.efsa.2026.9823_ref26","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Koutsoumanis, K., Allende, A., \u00c1lvarez\u2010 Ord\u00f3\u00f1ez, A., Bolton, D., Bover\u2010 Cid, S., Chemaly, M., De Cesare, A., Hilbert, F., Lindqvist, R., Nauta, M., Peixe, L., Ru, G., Simmons, M., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., Prieto Maradona, M., & Herman, L. (2023b). Scientific Opinion on the update of the list of qualified presumption of safety (QPS) recommended microorganisms intentionally added to food or feed as notified to EFSA. EFSA Journal, 21(1), 7747. https:\/\/doi.org\/10.2903\/j.efsa.2023.7747","DOI":"10.2903\/j.efsa.2023.7747"},{"key":"10.2903\/j.efsa.2026.9823_ref27","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Koutsoumanis, K., Allende, A., Alvarez\u2010Ord\u00f3\u00f1ez, A., Bolton, D., Bover\u2010Cid, S., Chemaly, M., De Cesare, A., Hilbert, F., Lindqvist, R., Nauta, M., Nonno, R., Peixe, L., Ru, G., Simmons, M., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., \u2026 Herman, L. (2023c). Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 18: Suitability of taxonomic units notified to EFSA until march 2023. EFSA Journal, 21(7), 8092. https:\/\/doi.org\/10.2903\/j.efsa.2023.8092","DOI":"10.2903\/j.efsa.2023.8092"},{"key":"10.2903\/j.efsa.2026.9823_ref28","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Koutsoumanis, K., Allende, A., Alvarez\u2010Ord\u00f3\u00f1ez, A., Bolton, D., Bover\u2010Cid, S., Chemaly, M., De Cesare, A., Hilbert, F., Lindqvist, R., Nauta, M., Nonno, R., Peixe, L., Ru, G., Simmons, M., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., \u2026 Herman, L. (2024a). Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 19: Suitability of taxonomic units notified to EFSA until September 2023. EFSA Journal, 22(1), 8517. https:\/\/doi.org\/10.2903\/j.efsa.2024.8517","DOI":"10.2903\/j.efsa.2024.8517"},{"key":"10.2903\/j.efsa.2026.9823_ref29","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Koutsoumanis, K., Allende, A., Alvarez\u2010Ord\u00f3\u00f1ez, A., Bolton, D., Bover\u2010Cid, S., Chemaly, M., De Cesare, A., Hilbert, F., Lindqvist, R., Nauta, M., Nonno, R., Peixe, L., Ru, G., Simmons, M., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., & Herman, L. (2024b). Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 20: Suitability of taxonomic units notified to EFSA until march 2024. EFSA Journal, 22(7), 8882. https:\/\/doi.org\/10.2903\/j.efsa.2024.8882","DOI":"10.2903\/j.efsa.2024.8882"},{"key":"10.2903\/j.efsa.2026.9823_ref30","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Allende, A., Alvarez\u2010Ord\u00f3\u00f1ez, A., Bortolaia, V., Bover\u2010Cid, S., De Cesare, A., Dohmen, W., Guillier, L., Jacxsens, L., Nauta, M., Mughini\u2010Gras, L., Ottoson, J., Peixe, L., Perez\u2010Rodriguez, F., Skandamis, P., Suffredini, E., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., Maradona, M. P., & Herman, L. (2025a). Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 22: Suitability of taxonomic units notified to EFSA until march 2025. EFSA Journal, 23(7), 9510. https:\/\/doi.org\/10.2903\/j.efsa.2025.9510","DOI":"10.2903\/j.efsa.2025.9510"},{"key":"10.2903\/j.efsa.2026.9823_ref31","doi-asserted-by":"crossref","unstructured":"EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards) , Allende, A., Alvarez\u2010Ord\u00f3\u00f1ez, A., Bortolaia, V., Bover\u2010Cid, S., De Cesare, A., Dohmen, W., Guillier, L., Jacxsens, L., Nauta, M., Mughini\u2010Gras, L., Ottoson, J., Peixe, L., Perez\u2010Rodriguez, F., Skandamis, P., Suffredini, E., Chemaly, M., Cocconcelli, P. S., Fern\u00e1ndez Esc\u00e1mez, P. S., & Herman, L. (2025b). Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 21: Suitability of taxonomic units notified to EFSA until September 2024. 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