{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:16:25Z","timestamp":1740179785920,"version":"3.37.3"},"reference-count":10,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"2","license":[{"start":{"date-parts":[[2021,8,22]],"date-time":"2021-08-22T00:00:00Z","timestamp":1629590400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RAM"],"abstract":"<jats:p>Introducci\u00f3n: Sugammadex es una ciclodextrina que revierte el bloqueo neuromuscular, especialmente de rocuronio. La incidencia de anafilaxia producida por su uso es de 1:1.000 y 1:20.000, se observa principalmente en sujetos de origen asi\u00e1tico.\nReporte de caso: Ni\u00f1o de 9 a\u00f1os, de raza asi\u00e1tica que tras la administraci\u00f3n de sugammadex, inmediatamente manifest\u00f3 un episodio de anafilaxia, la cual revirti\u00f3 con el uso de adrenalina y antihistam\u00ednicos. La triptasa s\u00e9rica a las 2 h fue de 27.7 \u03bcg\/L; a las 6 semanas fue 3 \u03bcg\/L. La prueba cut\u00e1nea a sugammadex 100 mg\/mL fue positiva. La prueba de activaci\u00f3n de bas\u00f3filos fue positiva con 20 mg\/mL sugammadex.\nConclusi\u00f3n: La relaci\u00f3n temporal de la administraci\u00f3n del medicamento, las manifestaciones cl\u00ednicas, la elevaci\u00f3n de la triptasa y las pruebas diagn\u00f3sticas realizadas, identificaron el episodio de anafilaxia asociado con hipersensibilidad por sugammadex.<\/jats:p>","DOI":"10.29262\/ram.v658i2.876","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T01:13:15Z","timestamp":1631841195000},"page":"137-139","source":"Crossref","is-referenced-by-count":2,"title":["Anafilaxia por sugammadex en paciente pedi\u00e1trico"],"prefix":"10.29262","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4719-8291","authenticated-orcid":false,"given":"Juana Bautista","family":"Joyanes-Romo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4861-5704","authenticated-orcid":false,"given":"Ana Isabel","family":"Navarro-Abad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3059-7429","authenticated-orcid":false,"given":"Jos\u00e9 Miguel","family":"Urra-Ardanaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4798-154X","authenticated-orcid":false,"given":"\u00d3scar","family":"Gonz\u00e1lez-Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7180-8539","authenticated-orcid":false,"given":"Alberto","family":"Palacios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9452-3317","authenticated-orcid":false,"given":"Jaime Vinicio","family":"Meneses-Sotomayor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9677-0792","authenticated-orcid":false,"given":"Marta","family":"Pascual","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0071-7629","authenticated-orcid":false,"given":"Ma. de Gracia","family":"Villanueva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2700-4565","authenticated-orcid":false,"given":"Davinia","family":"Garrido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1296-6748","authenticated-orcid":false,"given":"Pedro \u00c1ngel","family":"Galindo-Bonilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3365-4129","authenticated-orcid":false,"given":"Ana","family":"Joyanes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2021,8,22]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Min KC, Bondiskey P, Schulz V, Woo T, Assaid C, Yu W, et al. 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