{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:20:47Z","timestamp":1744258847504,"version":"3.40.4"},"reference-count":0,"publisher":"Colegio Mexicano de Inmunologia Clinica y Alergia, A. C.","issue":"4","license":[{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Alerg Mex"],"abstract":"<jats:p>Background: During surgery, the patient is exposed to multiple medications and molecules that can be associated with the development hypersensitivity, which makes it difficult to detect the causative agent of a perioperative reaction and makes it necessary to perform allergy tests.Case report: 53-year-old man who after a right knee arthroscopy was administered intravenous ketorolac; at 12 minutes, a pruriginous rash appeared on the chest, abdomen and limbs; infusion of the drug was immediately stopped and 100 mg intravenous hydrocortisone were administered. At 15 minutes, the patient experienced bilateral angioedema of the eyelids and a sensation of breathlessness, and oxygen was therefore administered, as well as 2 mg intravenous clemastine, 5 mg intravenous ranitidine and 20 \u00b5g subcutaneous adrenaline. Epidermal tests with 0.5\u00a0% chlorhexidine and serum chlorhexidine-specific immunoglobulin E (IgE) were performed, both with positive results. The patient recovered without complications; at discharge, he was prescribed intramuscular etofenamate.Conclusion: Perioperative anaphylaxis is a rare, but potentially fatal event. Proper identification of the drug or substance responsible for the reaction by using allergy tests decreases unnecessary pharmacological restrictions and avoids re-exposure.<\/jats:p>","DOI":"10.29262\/ram.v65i4.347","type":"journal-article","created":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T20:35:46Z","timestamp":1546461346000},"page":"431-436","source":"Crossref","is-referenced-by-count":2,"title":["Anafilaxia por clorhexidina en un contexto perioperatorio: diagn\u00f3stico y manejo","Chlorhexidine anaphylaxis in a perioperative context: diagnosis and management"],"prefix":"10.29262","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1126-0628","authenticated-orcid":false,"given":"Ana","family":"Calle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9558-3952","authenticated-orcid":false,"given":"Liliana","family":"Guevara-Salda\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7428-2413","authenticated-orcid":false,"given":"Ricardo","family":"Cardona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"11808","published-online":{"date-parts":[[2018,9,5]]},"container-title":["Revista Alergia M\u00e9xico"],"original-title":[],"link":[{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/347\/2481","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/347\/980","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/347\/911","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/download\/347\/2481","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T15:48:54Z","timestamp":1744213734000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.revistaalergia.mx\/ojs\/index.php\/ram\/article\/view\/347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,5]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,12,27]]}},"URL":"https:\/\/doi.org\/10.29262\/ram.v65i4.347","relation":{},"ISSN":["2448-9190","0002-5151"],"issn-type":[{"type":"electronic","value":"2448-9190"},{"type":"print","value":"0002-5151"}],"subject":[],"published":{"date-parts":[[2018,9,5]]}}}